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METTL3 Gains R/W Access to the Epitranscriptome.

Abstract：

:Epitranscriptomic marks are dynamically placed on mRNA by "writer" or "eraser" enzymes, while "readers" modulate their function accordingly. Lin et al. (2016) now report that the N6-methyladenosine:RNA methyltransferase METTL3 is both a writer and a reader, directly enhancing mRNA translation.

journal_name

Mol Cell

journal_title

Molecular cell

authors

Schumann U,Shafik A,Preiss T

doi

10.1016/j.molcel.2016.04.024

subject

Has Abstract

pub_date

2016-05-05 00:00:00

pages

323-324

issue

3

eissn

1097-2765

issn

1097-4164

pii

S1097-2765(16)30100-9

journal_volume

62

pub_type

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