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The first case of fungal endophthalmitis caused by Emericella nidulans after cataract surgery.

Abstract：

:Emericella nidulans is a species that has only rarely been implicated in human disease after cataract surgery. Here, we report the first postoperative case in the literature, as far as we know. The patient was a 50-year-old patient presented with mild anterior uveitis one week after cataract surgery, and hypopion developed over the next two days. First microbiological evaluation and the results of direct microscopy and cultures of the anterior chamber and vitreous samples were found to be negative. Despite vigorous topical and intravitreal (vancomycin and amikacin) therapy, the endophthalmitis did not improve. Anterior chamber paracentesis, vitreous tap and finally complete vitrectomy with removal of the capsular bag including the intraocular lens (IOL) were performed. The anterior chamber, vitreous fluid samples and IOL were submitted to the microbiology laboratory: the culture yielded E. nidulans growth. Ocular inflammation resolved and vision improved on intravenous, subconjunctival and long-term oral voriconazole treatment. E. nidulans can be an important cause of ocular fungal infections including endophthalmitis, and voriconazole seems to be effective for the treatment of E. nidulans endophthalmitis.

journal_name

J Mycol Med

journal_title

Journal de mycologie medicale

authors

Mutlu FM,Yildiran ST,Saracli MA,Gümral R,Durukan H,Sobaci G,Mutlu AG

doi

10.1016/j.mycmed.2015.12.010

subject

Has Abstract

pub_date

2016-09-01 00:00:00

pages

271-6

issue

3

eissn

1156-5233

issn

1773-0449

pii

S1156-5233(16)00011-1

journal_volume

26

pub_type

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