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Candida nivariensis: Identification strategy in mycological laboratories.

Abstract：

:Candida nivariensis is a cryptic fungal species classified within the Candida glabrata complex. It was described for the first time in 2005 by the means of DNA sequencing. We report a rare case of C. nivariensis deep-seated infection occurring in a 77-year-old man hospitalized for cysto-prostatectomy. Phenotypic testing based on the direct examination and the macroscopic features of the in vitro culture initially suggested C. glabrata species, while MALDI-TOF mass spectrometry enables correct identification. The isolate was found resistant to fluconazole, like in almost 20% of the reported cases. Herein, we present our practical strategy to reliably characterize this rare cryptic species. To date, MALDI-TOF mass spectrometry-based analysis showed very good results for such a purpose.

journal_name

J Mycol Med

journal_title

Journal de mycologie medicale

authors

Cartier N,Chesnay A,N'diaye D,Thorey C,Ferreira M,Haillot O,Bailly É,Desoubeaux G

doi

10.1016/j.mycmed.2020.101042

subject

Has Abstract

pub_date

2020-12-01 00:00:00

pages

101042

issue

4

eissn

1156-5233

issn

1773-0449

pii

S1156-5233(20)30161-X

journal_volume

30

pub_type

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