Disposition of 5-aminosalicylic acid by 5-aminosalicylic acid-delivering compounds.

abstract：BACKGROUND:Over the last few decades numerous regional and national registers have been established all over the world with the aim of improving survival in familial adenomatous polyposis (FAP). The Danish Polyposis Register was founded in 1971 and coordinates the screening and subsequent prophylactic colectomy of FAP ...

journal_title：Scandinavian journal of gastroenterology

authors： Bülow S,Bülow C,Nielsen TF,Karlsen L,Moesgaard F

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND:The peptoid CI-988 has previously been shown to have high affinity for the cholecystokinin (CCK)-B/gastrin receptor and has been reported to be a powerful CCK antagonist in many systems, although it has agonist activity on histidine decarboxylase in the rat. METHODS:In the present study the effect of CI-988...

journal_title：Scandinavian journal of gastroenterology

authors： Marvik R,Sandvik AK,Waldum HL

更新日期：1997-06-01 00:00:00

abstract：BACKGROUND:Recent studies have shown that hepatocyte growth factor (HGF) has a mitogenic and motogenic activity for gastric mucosal cells. The aim of this study is to ascertain the clinical significance of the expression of HGF and its receptor (c-met) during the course of gastric ulcer healing. METHODS:Ten patients w...

journal_title：Scandinavian journal of gastroenterology

authors： Hori K,Shiota G,Kawasaki H

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate whether changes in lymph node size in the hepatoduodenal ligament reflect changes in biochemical and histologic markers of cholestasis, hepatocellular damage, and humoral immunoreactivity in patients with primary biliary cirrhosis (PBC). METHODS:Twenty-three consecut...

journal_title：Scandinavian journal of gastroenterology

authors： Lyttkens K,Prytz H,Forsberg L,Hägerstrand I

更新日期：1995-10-01 00:00:00

abstract：:OBJECTIVE. Coeliac disease (CD) is associated with neurological disease, but there are little data on visual acuity in CD. The objective of this study was to examine visual acuity in undiagnosed and diagnosed CD. MATERIAL AND METHODS. Visual acuity was evaluated in Swedish male conscripts: 69 with undiagnosed CD (diag...

journal_title：Scandinavian journal of gastroenterology

authors： Mollazadegan K,Ludvigsson JF

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVES:The clinical impact of portal vein thrombosis (PVT) in cirrhotic patients remains unclear. The aim of the study is whether recanalization of acute PVT in nonmalignant cirrhotic patients is associated with their prognosis. MATERIALS AND METHODS:We identified subject with PVT in cirrhotic patients from instit...

journal_title：Scandinavian journal of gastroenterology

authors： Endo K,Oikawa T,Kakisaka K,Tamura A,Ehara S,Takikawa Y

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:Enteric neuropathy with mild inflammation (ganglionitis) has been described in several motility disorders including irritable bowel syndrome (IBS), enteric dysmotility (ED), slow-transit constipation (STC) and chronic intestinal pseudo-obstruction (CIPO). The purpose of this study was to test the hypothesis t...

journal_title：Scandinavian journal of gastroenterology

authors： Törnblom H,Lang B,Clover L,Knowles CH,Vincent A,Lindberg G

更新日期：2007-11-01 00:00:00

abstract：:Psychologic distress and gastric motor dysfunction have both been implicated in the pathogenesis of functional (non-ulcer) dyspepsia (FD). This study assesses the association between psychologic factors and gastric emptying in 28 FD patients. Subjects completed an extensive range of psychologic questionnaires and unde...

journal_title：Scandinavian journal of gastroenterology

authors： Bennett EJ,Kellow JE,Cowan H,Scott AM,Shuter B,Langeluddecke PM,Hoschl R,Jones MP,Tennant CC

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND:Dipeptidyl peptidase IV (DP IV, CD26), a serine protease with broad tissue distribution and known activity in serum, participates in T cell activation and promotes a Th1 cytokine response, a function in part attributable to its enzymatic activity. We hypothesized that the activity of DP IV in serum and expre...

journal_title：Scandinavian journal of gastroenterology

authors： Hildebrandt M,Rose M,Rüter J,Salama A,Mönnikes H,Klapp BF

更新日期：2001-10-01 00:00:00

abstract：:Enemas containing 1000 mg 5-ASA were administered to patients with active distal colitis in three separate studies: as a single dose in a neutral solution (pH 7.4); as a single dose in a slightly acidic, buffered suspension (pH 4.8); and as multiple doses once a day for 10 days with the acidic enema. 5-ASA was relativ...

journal_title：Scandinavian journal of gastroenterology

authors： Bondesen S,Nielsen OH,Jacobsen O,Rasmussen SN,Hansen SH,Halskov S,Binder V,Hvidberg EF

更新日期：1984-07-01 00:00:00

abstract：:In this study, a selective antagonist of cholecystokinin (CCK)-A receptors, loxiglumide, was used to evaluate the role of CCK in the control of the release of gastrin and pancreatic hormones (insulin, glucagon, pancreatic polypeptide (PP), and somatostatin) after stimulation with exogenous CCK and ingestion of a stand...

journal_title：Scandinavian journal of gastroenterology

authors： Konturek JW,Stoll R,Gutwinska-Konturek M,Konturek SJ,Domschke W

更新日期：1993-05-01 00:00:00

abstract：BACKGROUND:Spider angioma is a common sign in patients with liver cirrhosis, but the pathogenesis is still unclear. Alcohol and hyperestrogenemia are both possible etiologies. This study was designed to investigate the relationship of spider angiomas in patients with liver cirrhosis to alcohol, liver function test resu...

journal_title：Scandinavian journal of gastroenterology

authors： Li CP,Lee FY,Hwang SJ,Chang FY,Lin HC,Lu RH,Hou MC,Chu CJ,Chan CC,Luo JC,Lee SD

更新日期：1999-05-01 00:00:00

abstract：:Background: Endoscopic submucosal excavation (ESE), endoscopic full-thickness resection (EFTR) and submucosal tunneling endoscopic resection (STER) have been widely applied to upper gastrointestinal submucosal tumors (SMTs) originating from the muscularis propria (MP) layer in recent years. But until now, there are fe...

journal_title：Scandinavian journal of gastroenterology

authors： Xiu H,Zhao CY,Liu FG,Sun XG,Sun H,Liu XS

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Atrophic gastritis, a risk factor for gastric cancer, is a late consequence of Helicobacter pylori infection in approximately one-third of the infected patients. It has been suggested that gastric cancer would develop less frequently if H. pylori were eradicated. However, the prevalence of H. pylori infectio...

journal_title：Scandinavian journal of gastroenterology

authors： Kokkola A,Rautelin H,Puolakkainen P,Sipponen P,Färkkilä M,Haapiainen R,Kosunen TU

更新日期：2000-02-01 00:00:00

abstract：:A systematic approach is outlined for the preparation of a whole series of immunoreactive 125I-labeled gastrointestinal regulatory peptides with high specific radioactivities. In our hands, the theoretically superior Iodo-gen method has no more to offer than the harsher chloramine-T method in the iodination of secreti...

journal_title：Scandinavian journal of gastroenterology

authors： Burhol PG,Jorde R,Florholmen J,Jenssen TG,Vonen B

更新日期：1985-05-01 00:00:00

abstract：OBJECTIVE:Superoxide has been implicated in the pathogenesis of Helicobacter pylori-related diseases through inflammation. NADPH oxidase, a major source of superoxide generation, plays a critical role in H. pylori-related gastric inflammation. The aim of this study was to clarify the effect of the p22PHOX C242T polymor...

journal_title：Scandinavian journal of gastroenterology

authors： Tahara T,Shibata T,Wang F,Nakamura M,Okubo M,Yoshioka D,Sakata M,Nakano H,Hirata I,Arisawa T

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:It has been suggested that psychopathology in irritable bowel syndrome (IBS) patients is a function of patient status rather than of the disease. Although there are many studies comparing IBS patients, IBS non-patients, and controls with each other, no previous study has recruited all three groups from a rep...

journal_title：Scandinavian journal of gastroenterology

authors： Weinryb RM,Österberg E,Blomquist L,Hultcrantz R,Krakau I,Åsberg M

更新日期：2003-01-01 00:00:00

abstract：:Fifteen children who fulfilled the criteria of chronic non-specific diarrhea of infancy were evaluated for intestinal bacterial overgrowth. In 10 of 11 successfully investigated children we found bacterial overgrowth of the small intestine by upper respiratory tract microflora. In 9 of 10 children (group I) treated wi...

journal_title：Scandinavian journal of gastroenterology

authors： Dahlström KA,Danielsson L,Kalin M,Klingspor L

更新日期：1989-06-01 00:00:00

abstract：:The present study aims to identify differences between left and right colon adenocarcinoma arising from identical clonal cell and to find out if microenvironment has any influence on matrix metalloproteinase-2 (MMP2), p53 and β-catenin tumor expressions. MATERIAL AND METHODS. Rats (RNU) were submitted to cecostomy to ...

journal_title：Scandinavian journal of gastroenterology

authors： Priolli DG,Abrantes AM,Neves S,Gonçalves AC,Lopes CO,Martinez NP,Cardinalli IA,Ribeiro AB,Botelho MF

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVE:Activating mutations in the GUCY2C gene, which encodes the epithelial receptor guanylate cyclase C, cause diarrhea due to increased loss of sodium chloride to the intestinal lumen. Patients with familial GUCY2C diarrhea syndrome (FGDS) are predisposed to inflammatory bowel disease (IBD). We investigated wheth...

journal_title：Scandinavian journal of gastroenterology

authors： Tronstad RR,Polushina T,Brattbakk HR,Stansberg C,von Volkmann HL,Hanevik K,Ellinghaus E,Jørgensen SF,Ersland KM,Pham KD,Gilja OH,Hovdenak N,Hausken T,Vatn MH,Franke A,Knappskog PM,Le Hellard S,Karlsen TH,Fiskerstrand

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:We investigated whether individuals with positive coeliac disease antibodies but without small-bowel villous atrophy have mucosal inflammation implicating gluten-sensitivity. METHODS:Small-bowel mucosal morphology; CD3+, alphabeta+, and gammadelta+ T-cell receptor-bearing intraepithelial lymphocytes; and mu...

journal_title：Scandinavian journal of gastroenterology

authors： Kaukinen K,Collin P,Holm K,Karvonen AL,Pikkarainen P,Mäki M

更新日期：1998-09-01 00:00:00

abstract：:Fasting plasma levels of immunoreactive gastrin, somatostatin, and pancreatic polypeptide (PP) were determined in 67 patients with an endoscopically proven duodenal, pyloric, or prepyloric ulcer. Pretreatment gastrin (45.6 +/- 53.6 pmol/l, mean +/- S.D.) and somatostatin (54.5 +/- 27.5 pg/ml) did not differ significan...

journal_title：Scandinavian journal of gastroenterology

authors： Gustavsson S,Adami HO,Björklund O,Enander LK,Lundqvist G,Lööf L,Nordahl A

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND:Since the effect of exogenous glutathione (GSH) on overall hepatic GSH homeostasis is not known, the present study investigated the changes in the hepatic, biliary, and plasmatic GSH levels during GSH administration in intact rats. METHODS:An exteriorized biliary-duodenal fistula was established, and GSH (1...

journal_title：Scandinavian journal of gastroenterology

authors： Vendemiale G,Palmieri V,Palasciano G,Altomare E

更新日期：1994-11-01 00:00:00

abstract：:Objectives: Autoimmune pancreatitis (AIP) sometimes becomes complicated with pancreatic cysts, although their detailed characteristics and management strategy have not been fully determined. We aimed to clarify the efficiency of steroid therapy and the risk factors for cyst formation and cyst-related complications. Me...

journal_title：Scandinavian journal of gastroenterology

authors： Kuraishi Y,Watanabe T,Muraki T,Ashihara N,Ozawa M,Nakamura A,Kanai K,Hamano H,Kawa S

更新日期：2019-06-01 00:00:00

abstract：OBJECTIVE:Crohn's disease (CD) has been associated with low mucosal interleukin (IL)-10 production, but the mechanism behind this deficiency remains unclear. The aim of this study was to investigate IL-10 and interferon (IFN)-gamma production in intestinal CD4+ T cells from CD patients and healthy volunteers (HV) and t...

journal_title：Scandinavian journal of gastroenterology

authors： Hvas CL,Kelsen J,Agnholt J,Höllsberg P,Tvede M,Møller JK,Dahlerup JF

更新日期：2007-05-01 00:00:00

abstract：INTRODUCTION:Endoscopic retrograde cholangiopancreatography (ERCP) in patients with surgically altered upper gastrointestinal anatomy (SAA) is generally challenging despite the use of enteroscopy. After failed biliary cannulation, rendezvous technique (RV) can be an option to assist the biliary access. However, proper ...

journal_title：Scandinavian journal of gastroenterology

authors： Okuno M,Iwashita T,Yasuda I,Mabuchi M,Uemura S,Nakashima M,Doi S,Adachi S,Mukai T,Moriwaki H

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVE:In 1990, Lavelle and Kanagaratnam introduced Usefulness Index (UI) test for assessment of usefulness of clinical observations. Although, nonspecific abdominal pain (NSAP) is the most common diagnosis among secondary care patients with acute abdominal pain, the efficiency of UI test is rarely considered in NSA...

journal_title：Scandinavian journal of gastroenterology

authors： Eskelinen M,Lipponen P

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:Pancreatic cancer continues to be an urgent clinical problem. We used the novel DNA methyltransferase inhibitor Zebularine and the histone deacetylase inhibitor SAHA to investigate the epigenetic influence on viability and differentiation of the pancreatic cancer cell lines YAP C, DAN G and Panc-89 in vitro a...

journal_title：Scandinavian journal of gastroenterology

authors： Neureiter D,Zopf S,Leu T,Dietze O,Hauser-Kronberger C,Hahn EG,Herold C,Ocker M

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:Serial monitoring data for faecal calprotectin and lactoferrin during Crohn's disease (CD) therapy are scarce. The aim of this research was to study the behaviour of faecal biomarkers during CD therapy. MATERIAL AND METHODS:Adult CD patients (n = 19) needing therapy enhancement were prospectively recruited. ...

journal_title：Scandinavian journal of gastroenterology

authors： Sipponen T,Björkesten CG,Färkkilä M,Nuutinen H,Savilahti E,Kolho KL

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:Acute liver failure (ALF) is haemodynamically characterized by a hyperdynamic circulation. The aims of this study were to investigate the systemic and regional haemodynamics in ALF, to measure changes in nitric oxide metabolites (NOx) and to evaluate whether these haemodynamic disturbances could be attenuated...

journal_title：Scandinavian journal of gastroenterology

authors： Ytrebø LM,Sen S,Rose C,Davies NA,Nedredal GI,Fuskevaag OM,Ten Have GA,Prinzen FW,Williams R,Deutz NE,Jalan R,Revhaug A

更新日期：2006-11-01 00:00:00