Thermal limits on MV x-ray production by bremsstrahlung targets in the context of novel linear accelerators.

Abstract:

PURPOSE:To study the impact of target geometrical and linac operational parameters, such as target material and thickness, electron beam size, repetition rate, and mean current on the ability of the radiotherapy treatment head to deliver high-dose-rate x-ray irradiation in the context of novel linear accelerators capable of higher repetition rates/duty cycle than conventional clinical linacs. METHODS:The depth dose in a water phantom without a flattening filter and heat deposition in an x-ray target by 10 MeV pulsed electron beams were calculated using the Monte-Carlo code MCNPX, and the transient temperature behavior of the target was simulated by ANSYS. Several parameters that affect both the dose distribution and temperature behavior were investigated. The target was tungsten with a thickness ranging from 0 to 3 mm and a copper heat remover layer. An electron beam with full width at half maximum (FWHM) between 0 and3 mm and mean current of 0.05-2 mA was used as the primary beam at repetition rates of 100, 200, 400, and 800 Hz. RESULTS:For a 10 MeV electron beam with FWHM of 1 mm, pulse length of 5 μs, by using a thin tungsten target with thickness of 0.2 mm instead of 1 mm, and by employing a high repetition rate of 800 Hz instead of 100 Hz, the maximum dose rate delivered can increase two times from 0.57 to 1.16 Gy/s. In this simple model, the limiting factor on dose rate is the copper heat remover's softening temperature, which was considered to be 500°C in our study. CONCLUSIONS:A high dose rate can be obtained by employing thin targets together with high repetition rate electron beams enabled by novel linac designs, whereas the benefit of thin targets is marginal at conventional repetition rates. Next generation linacs used to increase dose rate need different target designs compared to conventional linacs.

journal_name

Med Phys

journal_title

Medical physics

authors

Wang J,Trovati S,Borchard PM,Loo BW Jr,Maxim PG,Fahrig R

doi

10.1002/mp.12615

subject

Has Abstract

pub_date

2017-12-01 00:00:00

pages

6610-6620

issue

12

eissn

0094-2405

issn

2473-4209

journal_volume

44

pub_type

杂志文章
  • Advanced statistical techniques applied to comprehensive FTIR spectra on human colonic tissues.

    abstract:PURPOSE:Colon cancer is a major public health problem due to its high disease rate and death toll worldwide. The use of FTIR microscopy in the field of cancer diagnosis has become attractive over the past 20 years. In the present study, the authors investigated the potential of FTIR microscopy to define spectral change...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3298013

    authors: Zwielly A,Mordechai S,Sinielnikov I,Salman A,Bogomolny E,Argov S

    更新日期:2010-03-01 00:00:00

  • Automated matching and segmentation of lymphoma on serial CT examinations.

    abstract::In patients with lymphoma, identification and quantification of the tumor extent on serial CT examinations is critical for assessing tumor response to therapy. In this paper, we present a computer method to automatically match and segment lymphomas in follow-up CT images. The method requires that target lymph nodes in...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2404617

    authors: Yan J,Zhao B,Curran S,Zelenetz A,Schwartz LH

    更新日期:2007-01-01 00:00:00

  • Constrained reconstruction: a superresolution, optimal signal-to-noise alternative to the Fourier transform in magnetic resonance imaging.

    abstract::Many problems in physics involve imaging objects with high spatial frequency content in a limited amount of time. The limitation of available experimental data leads to the infamous problem of diffraction limited data which manifests itself by causing ringing in the image. This ringing is due to the interference pheno...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.596427

    authors: Haacke EM,Liang ZP,Izen SH

    更新日期:1989-05-01 00:00:00

  • The thermal characteristics of different diodes on in vivo patient dosimetry.

    abstract::Diode sensitivity variations with temperature (SVWT) have been reported to vary from small negative values up to 0.6% per degrees C. Thus it is possible for diode calibration factors established at room temperature (approximately 20 degrees C) to yield errors in the range of -1% to +9% when diodes are placed on a pati...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1367862

    authors: Welsh KT,Reinstein LE

    更新日期:2001-05-01 00:00:00

  • Spectral analysis of mammographic images using a multitaper method.

    abstract:PURPOSE:Power spectral analysis in radiographic images is conventionally performed using a windowed overlapping averaging periodogram. This study describes an alternative approach using a multitaper technique and compares its performance with that of the standard method. This tool will be valuable in power spectrum est...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3676740

    authors: Wu G,Mainprize JG,Yaffe MJ

    更新日期:2012-02-01 00:00:00

  • Automated registration of large deformations for adaptive radiation therapy of prostate cancer.

    abstract::Available deformable registration methods are often inaccurate over large organ variation encountered, for example, in the rectum and bladder. The authors developed a novel approach to accurately and effectively register large deformations in the prostate region for adaptive radiation therapy. A software tool combinin...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3095777

    authors: Godley A,Ahunbay E,Peng C,Li XA

    更新日期:2009-04-01 00:00:00

  • Determination of exit skin dose for 192Ir intracavitary accelerated partial breast irradiation with thermoluminescent dosimeters.

    abstract:PURPOSE:Intracavitary accelerated partial breast irradiation (APBI) has become a popular treatment for early stage breast cancer in recent years due to its shortened course of treatment and simplified treatment planning compared to traditional external beam breast conservation therapy. However, the exit dose to the ski...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3429089

    authors: Raffi JA,Davis SD,Hammer CG,Micka JA,Kunugi KA,Musgrove JE,Winston JW Jr,Ricci-Ott TJ,DeWerd LA

    更新日期:2010-06-01 00:00:00

  • A framework for quantification and visualization of segmentation accuracy and variability in 3D lateral ventricle ultrasound images of preterm neonates.

    abstract:PURPOSE:Intraventricular hemorrhage (IVH) is a major cause of brain injury in preterm neonates. Three dimensional ultrasound (US) imaging systems have been developed to visualize 3D anatomical structure of preterm neonatal intracranial ventricular system with IVH and ventricular dilation. To allow quantitative analysis...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4932366

    authors: Chen Y,Qiu W,Kishimoto J,Gao Y,Chan RH,de Ribaupierre S,Fenster A,Chiu B

    更新日期:2015-11-01 00:00:00

  • SU-E-J-43: Autotuning Imaging Parameters in X-Ray Fluoroscopic Tracking for Dose Savings.

    abstract:PURPOSE:In fluoroscopy-guided clinical procedures that involve tracking objects over long treatment times, there is a need for reducing the amount of imaging dose delivered to the patient and the operating staff. In this study, we introduce a feedback metric to minimize tube current while maintaining a targeting precis...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4734878

    authors: Siddique S,Fiume E,Jaffray D

    更新日期:2012-06-01 00:00:00

  • TU-G-BRB-01: Continuous Path Optimization for Non-Coplanar Variant SAD IMRT Delivery Using C-Arm Machines.

    abstract:PURPOSE:To develop and investigate a continuous path optimization methodology to traverse prescribed non-coplanar IMRT beams with variant SADs, by orchestrating the couch and gantry movement with zero-collision, minimal patient motion consequence and machine travel time. METHODS:We convert the given collision zone def...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4735996

    authors: Ruan D,Dong P,Low D,Sheng K

    更新日期:2012-06-01 00:00:00

  • Model-based calculations of off-axis ratio of conic beams for a dedicated 6 MV radiosurgery unit.

    abstract:PURPOSE:Because the small-radius photon beams shaped by cones in stereotactic radiosurgery (SRS) lack lateral electronic equilibrium and a detector's finite cross section, direct experimental measurement of dosimetric data for these beams can be subject to large uncertainties. As the dose calculation accuracy of a trea...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3488900

    authors: Yang JN,Ding X,Du W,Pino R

    更新日期:2010-10-01 00:00:00

  • Scan pattern optimization for uniform proton beam scanning.

    abstract::Magnetic beam scanning allows one to spread proton beam over the desired radiation field area, improving beam utilization and conformity to the target area. This article discusses generic scan forms for generating uniform circular and rectangular fields and establishes criteria that can be applied to optimize selected...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3158731

    authors: Anferov VA

    更新日期:2009-08-01 00:00:00

  • Bremsstrahlung production at 50 MeV in different target materials and configurations.

    abstract::A combination of Monte Carlo, convolution, and experimental techniques have been used to investigate bremsstrahlung production at 50 MeV in full-range targets to produce narrow elementary photon beams for scanning. Calculations using the ITS 3.0 Monte Carlo system for various target designs, including particle transpo...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.597681

    authors: Sätherberg A,Andreo P,Karlsson M

    更新日期:1996-04-01 00:00:00

  • A simple model for transit dosimetry based on a water equivalent EPID.

    abstract:PURPOSE:The aim of this study was to demonstrate a new model for implementing a transit dosimetry system as a means of in vivo dose verification with a water equivalent electronic portal imaging device (WE-EPID) and a conventional treatment planning system (TPS). METHOD AND MATERIALS:A standard amorphous silicon (a-Si...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.12742

    authors: Deshpande S,Blake SJ,Xing A,Metcalfe PE,Holloway LC,Vial P

    更新日期:2018-03-01 00:00:00

  • A new technique to characterize CT scanner bow-tie filter attenuation and applications in human cadaver dosimetry simulations.

    abstract:PURPOSE:To present a noninvasive technique for directly measuring the CT bow-tie filter attenuation with a linear array x-ray detector. METHODS:A scintillator based x-ray detector of 384 pixels, 307 mm active length, and fast data acquisition (model X-Scan 0.8c4-307, Detection Technology, FI-91100 Ii, Finland) was use...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4932364

    authors: Li X,Shi JQ,Zhang D,Singh S,Padole A,Otrakji A,Kalra MK,Xu XG,Liu B

    更新日期:2015-11-01 00:00:00

  • A system for intensity modulated dose plan verification based on an experimental pencil beam kernel obtained by deconvolution.

    abstract::The number of intensity modulated radiation therapy (IMRT) procedures is continuously growing worldwide and it is necessary to develop tools for patient specific quality assurance (QA) that avoid using machine time that could be employed in treating additional patients. One way of achieving this goal is to perform a m...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2815359

    authors: Azcona JD,Burguete J

    更新日期:2008-01-01 00:00:00

  • Local patient dose diagnostic reference levels in pediatric interventional cardiology in Chile using age bands and patient weight values.

    abstract:PURPOSE:To present the results of a patient dose evaluation program in pediatric cardiology and propose local diagnostic reference levels (DRLs) for different types of procedure and age range, in addition to suggesting approaches to correlate patient dose values with patient weight. This study was the first conducted i...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4905116

    authors: Ubeda C,Miranda P,Vano E

    更新日期:2015-02-01 00:00:00

  • MRI-related FDA adverse event reports: A 10-yr review.

    abstract:PURPOSE:To provide an overview of the types of adverse events reported to the US Food and Drug Administration (US FDA) for magnetic resonance (MR) systems over a 10-yr period. METHODS:Two reviewers independently reviewed adverse events reported to FDA for MR systems from 1 January 2008 to 31 December 2017 and manually...

    journal_title:Medical physics

    pub_type: 杂志文章,评审

    doi:10.1002/mp.13768

    authors: Delfino JG,Krainak DM,Flesher SA,Miller DL

    更新日期:2019-12-01 00:00:00

  • X-ray scatter correction in breast tomosynthesis with a precomputed scatter map library.

    abstract:PURPOSE:To develop and evaluate the impact on lesion conspicuity of a software-based x-ray scatter correction algorithm for digital breast tomosynthesis (DBT) imaging into which a precomputed library of x-ray scatter maps is incorporated. METHODS:A previously developed model of compressed breast shapes undergoing mamm...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4866229

    authors: Feng SS,D'Orsi CJ,Newell MS,Seidel RL,Patel B,Sechopoulos I

    更新日期:2014-03-01 00:00:00

  • Depth dose characteristics of 24-MV x-ray beams at extended SSD.

    abstract::Depth dose characteristics of 24-MV beams from a medical linear accelerator at various SSDs have been measured. The dose buildup, percent depth dose (PDD), and output were measured using ionization chambers and a diode detector under full scatter. Surface dose ranged from 8% to 51% depending upon the collimator settin...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.596673

    authors: Jani SK,Pennington EC

    更新日期:1991-03-01 00:00:00

  • An automated procedure for the quality assurance of electron beam output and energy.

    abstract::In this article, we report on the development of a simple and accurate method for quality assurance of electron beam output and energy. Aluminum disks of thicknesses d(max) or d50 of the particular electron energy are positioned sequentially over a parallel-plate ion chamber and the ratio of the two signals is compare...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1688040

    authors: Woo MK,Videla NG

    更新日期:2004-05-01 00:00:00

  • Obtaining S values for rectangular-solid tumors inside rectangular-solid host organs.

    abstract::A method is described for obtaining S values between a tumor and its host organ for use with the MIRD formalism. It applies the point-source specific absorbed fractions for an infinite water medium, tabulated by Berger, to a rectangular solid of arbitrary dimensions which contains a rectangular tumor of arbitrary dime...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.596732

    authors: Stinchcomb TG,Durham JS,Fisher DR

    更新日期:1991-05-01 00:00:00

  • Monte Carlo dose calculations for a new ovoid shield system for carcinoma of the uterine cervix.

    abstract::The dose distribution for an ovoid with a new tungsten shielding design was determined using Monte Carlo simulation. Standard Cesium-137 tube sources, tungsten shielding, and aluminum ovoid applicator were each modeled as a collection of solid objects. Dose was calculated in planes above, below, in front of, and on th...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.598459

    authors: Weeks KJ

    更新日期:1998-12-01 00:00:00

  • Effects of tumor motion in GRID therapy.

    abstract::Clinical and biological evidence suggest that the success of GRID therapy in debulking large tumors depends on the high peak-to-valley contrast in the dose distribution. In this study, we show that the peaks and valleys can be significantly blurred out by respiration-induced tumor motion, possibly affecting the clinic...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2977538

    authors: Naqvi SA,Mohiuddin MM,Ha JK,Regine WF

    更新日期:2008-10-01 00:00:00

  • Ultrasonic tissue characterization via 2-D spectrum analysis: theory and in vitro measurements.

    abstract::A theoretical model is described for application in ultrasonic tissue characterization using a calibrated 2-D spectrum analysis method. This model relates 2-D spectra computed from ultrasonic backscatter signals to intrinsic physical properties of tissue microstructures, e.g., size, shape, and acoustic impedance. The ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2436978

    authors: Liu T,Lizzi FL,Ketterling JA,Silverman RH,Kutcher GJ

    更新日期:2007-03-01 00:00:00

  • The determination of electron density by the dual-energy Compton scatter method.

    abstract::The intensity of Compton scattered photons is directly proportional to the electron density of a substance; therefore it is possible to detect changes in electron density by this noninvasive method. The source-detector geometry has been varied to study the effects of geometry on the calculated electron density values,...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.595730

    authors: Huddleston AL,Sackler JP

    更新日期:1985-01-01 00:00:00

  • Recent progress in x-ray stereoscopes.

    abstract::An improved reconstructed stereoscopic x-ray image display system, based on the principle of binocular parallax, is described. Pulse-synchronized operation of two triode x-ray tubes and one plumbicon TV camera is employed to separate the left and right images for presentation to the two eyes, respectively. The princip...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.595365

    authors: Zhang S,King PH,Pang XD

    更新日期:1983-09-01 00:00:00

  • Investigation of effective decision criteria for multiobjective optimization in IMRT.

    abstract:PURPOSE:To investigate how using different sets of decision criteria impacts the quality of intensity modulated radiation therapy (IMRT) plans obtained by multiobjective optimization. METHODS:A multiobjective optimization evolutionary algorithm (MOEA) was used to produce sets of IMRT plans. The MOEA consisted of two i...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3589128

    authors: Holdsworth C,Stewart RD,Kim M,Liao J,Phillips MH

    更新日期:2011-06-01 00:00:00

  • Model-based geometric calibration for medical x-ray systems.

    abstract:PURPOSE:Currently applied calibration approaches lead to satisfying 3D roadmapping overlay and 3D reconstruction accuracies; however, the required calibration times are extensive. The aim of this paper is the introduction of a novel model-based approach for geometric system calibrations, leading to a significant reduct...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4931964

    authors: van der Maas R,de Jager B,Steinbuch M,Dries J

    更新日期:2015-11-01 00:00:00

  • SU-E-J-46: Use of Brainlab-ExacTrac IGRT with Dot-Decimal Electron Compensator(BolusECT) for Accurate Patient Positioning.

    abstract:PURPOSE:To Validate Brainlab-ExacTrac IGRT with Dot-Decimal electron compensator(BolusECT) for accurate patient positioning. METHODS:Dot-Decimal electron compensators(BolusECT) are used to achieve conformal dose distributions and greater sparing to normal structures for cases with varying patient contours and treated ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4734881

    authors: Prabhu A,Saini D,Patadiya B,Shankar R,Garthwaite T

    更新日期:2012-06-01 00:00:00