Scan pattern optimization for uniform proton beam scanning.

Abstract:

:Magnetic beam scanning allows one to spread proton beam over the desired radiation field area, improving beam utilization and conformity to the target area. This article discusses generic scan forms for generating uniform circular and rectangular fields and establishes criteria that can be applied to optimize selected scan patterns. During construction of the Midwest Proton Radiotherapy Institute (MPRI), Indiana University developed a magnetically scanned beam spreading system for the 3 m long gantry nozzle. Based on the commissioning experience, criteria for optimizing the scan patterns were derived. A numerical integration model was used to perform initial optimization of the resulting dose distribution. The selected scan patterns were then experimentally validated via test irradiation of Gafchromic films. Generic spiral and linear scan forms are proposed capable of delivering uniform circular and rectangular fields in continuous scanning mode. The test irradiations performed indicate that dose uniformity is within +/- 3% for both scan forms and that penumbra of the uncollimated field can approach the radius of the pristine beam spot. A well designed uniform scanning system can have a large library of uniform circular and rectangular fields of different sizes, which would increase beam utilization and minimize out-of-field dose to the patient.

journal_name

Med Phys

journal_title

Medical physics

authors

Anferov VA

doi

10.1118/1.3158731

subject

Has Abstract

pub_date

2009-08-01 00:00:00

pages

3560-7

issue

8

eissn

0094-2405

issn

2473-4209

journal_volume

36

pub_type

杂志文章
  • Signal and noise transfer properties of CMOS based active pixel flat panel imager coupled to structured CsI:Tl.

    abstract::Complementary metal-oxide-semiconductors (CMOS) active pixel sensors can be optically coupled to CsI:Tl phosphors forming a indirect active pixel flat panel imager (APFPI) for high performance medical imaging. The aim of this work is to determine the x-ray imaging capabilities of CMOS-based APFPI and study the signal ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3036117

    authors: Arvanitis CD,Bohndiek SE,Blakesley J,Olivo A,Speller RD

    更新日期:2009-01-01 00:00:00

  • Dose distributions of a proton beam for eye tumor therapy: hybrid pencil-beam ray-tracing calculations.

    abstract::For the case of eye tumor therapy with protons, improvements are introduced compared to the standard dose calculation which implies straight-line optics and the constant-density assumption for the eye and its surrounding. The progress consists of (i) taking account of the lateral scattering of the protons in tissue by...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2168067

    authors: Rethfeldt C,Fuchs H,Gardey KU

    更新日期:2006-03-01 00:00:00

  • SU-E-T-576: Investigation of Combining Modulated Electron Beams with Intensity Modulated Photons for Radiation Therapy of Breast Cases.

    abstract:PURPOSE:Modulated electron radiation therapy (MERT) can offer significant advantages for breast treatments over conventional radiotherapy in terms of sparing distal critical structures. While intensity modulated radiation therapy (IMRT) has the advantage of achieving better dose homogeneity inside the target combining ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4735665

    authors: Eldib A,Li J,Jin L,Ma C

    更新日期:2012-06-01 00:00:00

  • Dosimetric impact of geometric errors due to respiratory motion prediction on dynamic multileaf collimator-based four-dimensional radiation delivery.

    abstract::The synchronization of dynamic multileaf collimator (DMLC) response with respiratory motion is critical to ensure the accuracy of DMLC-based four dimensional (4D) radiation delivery. In practice, however, a finite time delay (response time) between the acquisition of tumor position and multileaf collimator response ne...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1915017

    authors: Vedam S,Docef A,Fix M,Murphy M,Keall P

    更新日期:2005-06-01 00:00:00

  • Poster - Thurs Eve-10: The accuracy of MU calculations for enhanced dynamic wedge with the Varian's anisotropic analytical algorithm.

    abstract::The Anisotropic Analytical Algorithm (AAA) of the Varian Eclipse treatment planning system calculates absolute dose for a variety of beam settings including those with an enhanced dynamic wedge (EDW). This algorithm has gone through a number of version updates since it was first released in July 2005. Previous version...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2965929

    authors: Salomons G,Kerr A,Mei X,Patel D

    更新日期:2008-07-01 00:00:00

  • Normalized dose data for upper gastrointestinal tract contrast studies performed to infants.

    abstract::The aim of the current study was to (a) provide normalized dose data for the estimation of the radiation dose from upper gastrointestinal tract contrast (UGIC) studies carried out to infants and (b) estimate the average patient dose and risks associated with radiation from UGIC examinations performed in our institutio...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2181297

    authors: Damilakis J,Stratakis J,Raissaki M,Perisinakis K,Kourbetis N,Gourtsoyiannis N

    更新日期:2006-04-01 00:00:00

  • Quantification of breast density with dual energy mammography: a simulation study.

    abstract::Breast density, the percentage of glandular breast tissue, has been identified as an important yet underutilized risk factor in the development of breast cancer. A quantitative method to measure breast density with dual energy imaging was investigated using a computer simulation model. Two configurations to measure br...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3002308

    authors: Ducote JL,Molloi S

    更新日期:2008-12-01 00:00:00

  • Technical Note: Comparison of megavoltage, dual-energy, and single-energy CT-based μ-maps for a four-channel breast coil in PET/MRI.

    abstract:PURPOSE:The purpose of this study was to describe and evaluate methods for calculating a megavoltage computed tomography (MVCT)-derived MR hardware attenuation map (μ-map) and dual-energy CT (DECT) for 511 keV photons. METHODS:Phantom measurements were acquired on a whole-body hybrid PET/MRI system, using a four-chann...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.12407

    authors: Patrick JC,Terry Thompson R,So A,Butler J,Faul D,Stodilka RZ,Yartsev S,Prato FS,Gaede S

    更新日期:2017-09-01 00:00:00

  • The effect of dose calculation uncertainty on the evaluation of radiotherapy plans.

    abstract::Monte Carlo dose calculations will potentially reduce systematic errors that may be present in currently used dose calculation algorithms. However, Monte Carlo calculations inherently contain random errors, or statistical uncertainty, the level of which decreases inversely with the square root of computation time. Our...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.598916

    authors: Keall PJ,Siebers JV,Jeraj R,Mohan R

    更新日期:2000-03-01 00:00:00

  • Second cancer incidence risk estimates using BEIR VII models for standard and complex external beam radiotherapy for early breast cancer.

    abstract:PURPOSE:To compare organ specific cancer incidence risks for standard and complex external beam radiotherapy (including cone beam CT verification) following breast conservation surgery for early breast cancer. METHOD:Doses from breast radiotherapy and kilovoltage cone beam CT (CBCT) exposures were obtained from thermo...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4748332

    authors: Donovan EM,James H,Bonora M,Yarnold JR,Evans PM

    更新日期:2012-10-01 00:00:00

  • Cascaded systems analysis of noise reduction algorithms in dual-energy imaging.

    abstract::An important aspect of dual-energy (DE) x-ray image decomposition is the incorporation of noise reduction techniques to mitigate the amplification of quantum noise. This article extends cascaded systems analysis of imaging performance to DE imaging systems incorporating linear noise reduction algorithms. A general ana...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2826556

    authors: Richard S,Siewerdsen JH

    更新日期:2008-02-01 00:00:00

  • SU-E-T-567: Improve Dose Conformity with IMRT Using Shorter Source to Tumor Distance.

    abstract:PURPOSE:To reduce the potential of late toxicity (tissue necrosis and cognitive function loss) from brain radiotherapy, we studied a novel planning technique for MLC-equipped linear accelerators (LINACS) that reduces the high doses delivered outside the PTV, enhancing radiation dose conformity. METHODS:The feasibility...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4735656

    authors: Yang W,Sandler H,Fraass B

    更新日期:2012-06-01 00:00:00

  • Dose and detectability for a cone-beam C-arm CT system revisited.

    abstract:PURPOSE:The authors had previously published measurements of the detectability of disk-shaped contrast objects in images obtained from a C-arm CT system. A simple approach based on Rose's criterion was used to scale the date, assuming the threshold for the smallest diameter detected should be inversely proportional to ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3397465

    authors: Ganguly A,Yoon S,Fahrig R

    更新日期:2010-05-01 00:00:00

  • Smoothing intensity-modulated treatment delivery under hardware constraints.

    abstract::A method is developed to smooth intensity-modulated beam delivery while considering hardware constraints. The method uses matrix algebra to model MLC leaf motion and hardware constraints such as interleaf digitization, synchronization requirements, and intersegment field abutment to deliver intensity modulated beam se...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1521121

    authors: Ma L

    更新日期:2002-12-01 00:00:00

  • Measurement of dose distributions using film in therapeutic electron beams.

    abstract::The feasibility of using film dosimetry data as the input data for patient treatment planning was evaluated. The central-axis depth dose and the off-axis ratios obtained from film measurements in a solid phantom were compared with those of ion-chamber measurements in water. Two techniques were used to generate isodose...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.596409

    authors: Shiu AS,Otte VA,Hogstrom KR

    更新日期:1989-11-01 00:00:00

  • Incorporation of treatment plan spatial and temporal dose patterns into a prostate intrafractional motion management strategy.

    abstract:PURPOSE:Periodic MV∕KV radiographs taken during volumetric modulated arc therapy (VMAT) for hypofractionated treatment provide guidance in intrafractional motion management. The choice of imaging frequency and timing are key components in delivering the desired dose while reducing associated overhead such as imaging do...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4742846

    authors: Zhang P,Hunt M,Happersett L,Cox B,Mageras G

    更新日期:2012-09-01 00:00:00

  • Absolute depth-dose-rate measurements for an 192Ir HDR brachytherapy source in water using MOSFET detectors.

    abstract::Reported MOSFET measurements concern mostly external radiotherapy and in vivo dosimetry. In this paper, we apply the technique for absolute dosimetry in the context of HDR brachytherapy using an 192Ir source. Measured radial dose rate distributions in water for different planes perpendicular to the source axis are pre...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2198168

    authors: Zilio VO,Joneja OP,Popowski Y,Rosenfeld A,Chawla R

    更新日期:2006-06-01 00:00:00

  • Analysis of Fourier-domain task-based detectability index in tomosynthesis and cone-beam CT in relation to human observer performance.

    abstract:PURPOSE:Design and optimization of medical imaging systems benefit from accurate theoretical modeling that identifies the physical factors governing image quality, particularly in the early stages of system development. This work extends Fourier metrics of imaging performance and detectability index (d') to tomosynthes...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3560428

    authors: Gang GJ,Lee J,Stayman JW,Tward DJ,Zbijewski W,Prince JL,Siewerdsen JH

    更新日期:2011-04-01 00:00:00

  • 3D modeling of effects of increased oxygenation and activity concentration in tumors treated with radionuclides and antiangiogenic drugs.

    abstract:PURPOSE:Formation of new blood vessels (angiogenesis) in response to hypoxia is a fundamental event in the process of tumor growth and metastatic dissemination. However, abnormalities in tumor neovasculature often induce increased interstitial pressure (IP) and further reduce oxygenation (pO2) of tumor cells. In radiot...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3615164

    authors: Lagerlöf JH,Kindblom J,Bernhardt P

    更新日期:2011-08-01 00:00:00

  • Segmentation and tracking of lung nodules via graph-cuts incorporating shape prior and motion from 4D CT.

    abstract:PURPOSE:We have developed a robust tool for performing volumetric and temporal analysis of nodules from respiratory gated four-dimensional (4D) CT. The method could prove useful in IMRT of lung cancer. METHODS:We modified the conventional graph-cuts method by adding an adaptive shape prior as well as motion informatio...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.12690

    authors: Cha J,Farhangi MM,Dunlap N,Amini AA

    更新日期:2018-01-01 00:00:00

  • Constrained reconstruction: a superresolution, optimal signal-to-noise alternative to the Fourier transform in magnetic resonance imaging.

    abstract::Many problems in physics involve imaging objects with high spatial frequency content in a limited amount of time. The limitation of available experimental data leads to the infamous problem of diffraction limited data which manifests itself by causing ringing in the image. This ringing is due to the interference pheno...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.596427

    authors: Haacke EM,Liang ZP,Izen SH

    更新日期:1989-05-01 00:00:00

  • SU-E-T-459: Radiobiological Evaluation of Implant Duration and Radionuclide Selection for COMS Eye Plaque Brachytherapy Using an Objective Function.

    abstract:PURPOSE:The biologically effective dose (BED) of temporary brachytherapy treatments is a function of both chosen radionuclide (R) and implant duration (T). This study endeavored to evaluate BED delivered to the tumor volume and surrounding ocular structures as a function of plaque position (P), prescription dose, R, an...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4735548

    authors: Gagne N,Rivard M

    更新日期:2012-06-01 00:00:00

  • An introduction to molecular imaging in radiation oncology: a report by the AAPM Working Group on Molecular Imaging in Radiation Oncology (WGMIR).

    abstract::Molecular imaging is the direct or indirect noninvasive monitoring and recording of the spatial and temporal distribution of in vivo molecular, genetic, and/or cellular processes for biochemical, biological, diagnostic, or therapeutic applications. Molecular images that indicate the presence of malignancy can be acqui...

    journal_title:Medical physics

    pub_type: 杂志文章,评审

    doi:10.1118/1.4819818

    authors: Munley MT,Kagadis GC,McGee KP,Kirov AS,Jang S,Mutic S,Jeraj R,Xing L,Bourland JD

    更新日期:2013-10-01 00:00:00

  • The importance of computed tomography slice thickness in radiographic patient positioning for radiosurgery.

    abstract::A new radiographic patient positioning technique developed for radiosurgery has been analyzed to show the effect of computed tomography (CT) slice thickness on the precision of target localization during treatment. The positioning technique establishes the pose of the patient's anatomy during treatment by comparing tr...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.598500

    authors: Murphy MJ

    更新日期:1999-02-01 00:00:00

  • A general model of microcirculatory blood flow effects in gradient sensitized MRI.

    abstract::A general expression is derived for the NMR signal from a fluid undergoing random directional flow such as encountered within the microcirculation. The dependence of the echo amplitude on flow velocity, sample morphology, and experimental parameters are described in terms of a temporal velocity autocorrelation functio...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.597170

    authors: Kennan RP,Gao JH,Zhong J,Gore JC

    更新日期:1994-04-01 00:00:00

  • An optimized ultrasound detector for photoacoustic breast tomography.

    abstract:PURPOSE:Photoacoustic imaging has proven to be able to detect vascularization-driven optical absorption contrast associated with tumors. In order to detect breast tumors located a few centimeter deep in tissue, a sensitive ultrasound detector is of crucial importance for photoacoustic mammography. Further, because the ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4792462

    authors: Xia W,Piras D,van Hespen JC,van Veldhoven S,Prins C,van Leeuwen TG,Steenbergen W,Manohar S

    更新日期:2013-03-01 00:00:00

  • Mixed model phase evolution for correction of magnetic field inhomogeneity effects in 3D quantitative gradient echo-based MRI.

    abstract:PURPOSE:In 3D gradient echo magnetic resonance imaging (MRI), strong field gradients B0macro are visually observed at air/tissue interfaces. At low spatial resolution in particular, the respective field gradients lead to an apparent increase in intravoxel dephasing, and subsequently, to signal loss or inaccurate R2* es...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.12318

    authors: Fatnassi C,Boucenna R,Zaidi H

    更新日期:2017-07-01 00:00:00

  • The properties of the ultramicrocylindrical ionization chamber for small field used in stereotactic radiosurgery.

    abstract::Accurate dosimetry of small-field photon beams tends to be difficult to perform due to the presence of lateral electronic disequilibrium and steep dose gradients. In stereotactic radiosurgery (SRS), small fields of 6-30 mm in diameter are used. Generally thermoluminescence dosimetry chips, Farmer, Thimble ion chamber,...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1350437

    authors: Vahc YW,Chung WK,Park KR,Lee JY,Lee YH,Kwon O,Kim S

    更新日期:2001-03-01 00:00:00

  • A water phantom controller for automated acquisition of linac beam parameters.

    abstract::Three-dimensional water phantoms are routinely used when acquiring the data necessary to commission medical linear accelerators. A new water phantom controller has been developed at our institution that is unique in several aspects. The water phantom controller is based on an IBM XT compatible computer. This has been ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.596414

    authors: Schmid MG,Morris RL

    更新日期:1989-01-01 00:00:00

  • Deformable mapping technique to correlate lesions in digital breast tomosynthesis and automated breast ultrasound images.

    abstract:PURPOSE:To develop a deformable mapping technique to match corresponding lesions between digital breast tomosynthesis (DBT) and automated breast ultrasound (ABUS) images. METHODS:External fiducial markers were attached to the surface of two CIRS multi-modality compressible breast phantoms (A and B) containing multiple...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.13113

    authors: Green CA,Goodsitt MM,Brock KK,Davis CL,Larson ED,Lau JH,Carson PL

    更新日期:2018-10-01 00:00:00