Advanced statistical techniques applied to comprehensive FTIR spectra on human colonic tissues.

abstract：PURPOSE:Ablative hyperthermia (>55 °C) has been used as a definitive treatment for accessible solid tumors not amenable to surgery, whereas mild hyperthermia (40-45 °C) has been shown effective as an adjuvant for both radiotherapy and chemotherapy. An optimal mild hyperthermia treatment is spatially accurate, with prec...

journal_title：Medical physics

authors： Partanen A,Tillander M,Yarmolenko PS,Wood BJ,Dreher MR,Kohler MO

更新日期：2013-01-01 00:00:00

abstract：:In intensity modulated radiation treatments (IMRT), the position of the field edges and the modulation within the beam are often achieved with a multileaf collimator (MLC). During the MLC calibration process, due to the finite accuracy of leaf position measurements, a systematic error may be introduced to leaf positio...

journal_title：Medical physics

authors： Parent L,Seco J,Evans PM,Dance DR,Fielding A

更新日期：2006-09-01 00:00:00

abstract：PURPOSE:Small animal immobilization devices facilitate positioning of animals for reproducible imaging and accurate focal radiation therapy. In this study, the authors demonstrate the use of three-dimensional (3D) printing technology to fabricate a custom-designed mouse head restraint. The authors evaluate the accuracy...

journal_title：Medical physics

authors： Zarghami N,Jensen MD,Talluri S,Foster PJ,Chambers AF,Dick FA,Wong E

更新日期：2015-11-01 00:00:00

abstract：:Computer-aided diagnosis (CAD) has been a major field of research for the past few decades. CAD uses machine learning methods to analyze imaging and/or nonimaging patient data and makes assessment of the patient's condition, which can then be used to assist clinicians in their decision-making process. The recent succe...

journal_title：Medical physics

authors： Chan HP,Hadjiiski LM,Samala RK

更新日期：2020-06-01 00:00:00

abstract：PURPOSE:Both spatial and biological information are necessary in order to perform true optimization of a treatment plan and for predicting clinical outcome. The goal of this work is to develop an enhanced treatment plan evaluation tool which incorporates biological parameters and retains spatial dose information. METH...

journal_title：Medical physics

authors： Zhao B,Joiner MC,Orton CG,Burmeister J

更新日期：2010-11-01 00:00:00

abstract：PURPOSE:The authors investigate the impact that incremental increases in the level of detail of patient-specific prior information have on image quality and the convergence behavior of an inversion algorithm in the context of near-field microwave breast imaging. A methodology is presented that uses image quality measur...

journal_title：Medical physics

authors： Kurrant D,Baran A,LoVetri J,Fear E

更新日期：2017-12-01 00:00:00

abstract：PURPOSE:It is important for many quantitative brain studies to label meaningful anatomical regions in MR brain images. However, due to high complexity of brain structures and ambiguous boundaries between different anatomical regions, the anatomical labeling of MR brain images is still quite a challenging task. In many ...

journal_title：Medical physics

authors： Ma G,Gao Y,Wu G,Wu L,Shen D

更新日期：2016-02-01 00:00:00

abstract：:The Los Alamos code MCNP4A (Monte Carlo N-Particle version 4A) is currently used to simulate a variety of problems ranging from nuclear reactor analysis to boron neutron capture therapy. A graphical user interface has been developed that automatically sets up the MCNP4A geometry and radiation source requirements for a...

journal_title：Medical physics

authors： DeMarco JJ,Solberg TD,Smathers JB

更新日期：1998-01-01 00:00:00

abstract：PURPOSE:Dosimetry with ionization chambers in clinical ion beams for radiation therapy requires correction for recombination effects. However, common radiation protocols discriminate between initial and general recombination and provide no universal correction method for the presence of both recombination types in ion ...

journal_title：Medical physics

authors： Christensen JB,Tölli H,Bassler N

更新日期：2016-10-01 00:00:00

abstract：PURPOSE:The aim of in vivo skin dosimetry was to measure the absorbed dose to the skin during radiotherapy, when treatment planning calculations cannot be relied on. It is of particularly importance in hypo-fractionated stereotactic modalities, where excessive dose can lead to severe skin toxicity. Currently, commercia...

journal_title：Medical physics

authors： Vicoroski N,Espinoza A,Duncan M,Oborn BM,Carolan M,Metcalfe P,Menichelli D,Perevertaylo VL,Lerch MLF,Rosenfeld AB,Petasecca M

更新日期：2017-10-01 00:00:00

abstract：PURPOSE:This paper describes the clinical implementation and medical commissioning of the MedAustron Particle Therapy Accelerator (MAPTA) for non-isocentric scanned proton beam treatments. METHODS:Medical physics involvement during technical commissioning work is presented. Acceptance testing procedures, including adv...

journal_title：Medical physics

authors： Grevillot L,Osorio Moreno J,Letellier V,Dreindl R,Elia A,Fuchs H,Carlino A,Kragl G,Palmans H,Vatnitsky S,Stock M

更新日期：2020-02-01 00:00:00

abstract：PURPOSE:To evaluate the availability and performance of pencil beam algorithm for fast neutrons radiotherapy dose calculations and to achieve improvements in universality, speed and inhomogeneities corrections. METHODS:Pencil beam (PB) method uses integration of dose kernel cross field size to estimate dose distributi...

journal_title：Medical physics

authors： Moiseev A,Klimanov V

更新日期：2012-06-01 00:00:00

abstract：:Many problems in physics involve imaging objects with high spatial frequency content in a limited amount of time. The limitation of available experimental data leads to the infamous problem of diffraction limited data which manifests itself by causing ringing in the image. This ringing is due to the interference pheno...

journal_title：Medical physics

authors： Haacke EM,Liang ZP,Izen SH

更新日期：1989-05-01 00:00:00

abstract：:When treating prostate cancer using high dose rate (HDR) brachytherapy, overdosing the rectal wall may lead to post-treatment rectal complications. An area of concern is related to how the rectal wall dose is calculated by treatment planning systems (TPSs). TPSs are used to calculate the dose delivered to the rectal w...

journal_title：Medical physics

authors： Kwan IS,Wilkinson D,Cutajar D,Lerch M,Rosenfeld A,Howie A,Bucci J,Chin Y,Perevertaylo VL

更新日期：2009-01-01 00:00:00

abstract：PURPOSE:Cortical thickness and density are critical components in determining the strength of bony structures. Computed tomography (CT) is one possible modality for analyzing the cortex in 3D. In this paper, a model-based approach for measuring the cortical bone thickness and density from clinical CT images is proposed...

journal_title：Medical physics

authors： Humbert L,Hazrati Marangalou J,Del Río Barquero LM,van Lenthe GH,van Rietbergen B

更新日期：2016-04-01 00:00:00

abstract：:Accurate and reliable thermometry is essential in the development of microwave-induced hyperthermal cancer therapy. While temperature measurements in strong electromagnetic fields usually require special sensors, this does not hold true for interstitial radiator/sensor systems. Miniature thermistors (with metallic lea...

journal_title：Medical physics

authors： Samaras GM,Rosenbloom S,Cheung AY

更新日期：1983-05-01 00:00:00

abstract：PURPOSE:In this work the performance of a compact multiresolution and multicontrast x-ray phase system based on edge illumination is investigated. It has been designed for small animal imaging and with a limited footprint for ease of deployment in laboratories. METHODS:The presented edge illumination system is based o...

journal_title：Medical physics

authors： Massimi L,Meganck JA,Towns R,Olivo A,Endrizzi M

更新日期：2020-10-27 00:00:00

abstract：PURPOSE:External beam radiation therapy (EBRT) usually uses heterogeneous dose distributions in a given volume. Designing detectors for quality control of these treatments is still a developing subject. The size of the detectors should be small to enhance spatial resolution and ensure low perturbation of the beam. A hi...

journal_title：Medical physics

authors： Barbés B,Azcona JD,Burguete J,Martí-Climent JM

更新日期：2014-01-01 00:00:00

abstract：PURPOSE:To propose a method to calculate the tissue phantom ratio (TPR) using the depth dose and to compare the proposed method with two other methods. METHODS:An analytical dose model from Bjärngard was used to describe the depth dose and the TPR. The parameters of the model were derived from depth dose measurements,...

journal_title：Medical physics

authors： Ramos Garcia LI,Almansa JF

更新日期：2011-05-01 00:00:00

abstract：:A simple approach was developed that calculates the output factors and tissue maximum ratio of an asymmetric field at any point within the open field, and specifically both at the central axis (when the jaws do not shadow it) and at the effective center of the open field, using the existing tables for symmetric fields...

journal_title：Medical physics

authors： Rosenberg I,Chu JC,Saxena V

更新日期：1995-01-01 00:00:00

abstract：:Intensity modulated radiation therapy (IMRT) treatment planning typically considers beam optimization and beam delivery as separate tasks. Following optimization, a multi-leaf collimator (MLC) or other beam delivery device is used to generate fluence patterns for patient treatment delivery. Due to limitations and char...

journal_title：Medical physics

authors： Siebers JV,Lauterbach M,Keall PJ,Mohan R

更新日期：2002-06-01 00:00:00

abstract：PURPOSE:A major challenge of four dimensional computed tomography (4DCT) in treatment planning and delivery has been the lack of respiration amplitude and phase reproducibility during image acquisition. The implementation of a prospective gating algorithm would ensure that images would be acquired only during user-spec...

journal_title：Medical physics

authors： White BM,Low DA,Zhao T,Wuenschel S,Lu W,Lamb JM,Mutic S,Bradley JD,El Naqa I

更新日期：2011-03-01 00:00:00

abstract：:Transmission data for 4-MV bremsstrahlung beams have been measured with a combination of lead and aluminum attenuators. From these data, the original energy spectra have been reconstructed using an iterative least-squares technique, previously evaluated by simulation studies. The spectra on the central axis for three ...

journal_title：Medical physics

authors： Huang PH,Kase KR,Bjärngard BE

更新日期：1983-11-01 00:00:00

abstract：:This study compared air exposures during conventional dental and maxillofacial radiography and similar views using free-focus radiography with conventional image receptors. The results show that periapical type surveys on nonscreen film placed extraorally or in the buccal fold may be carried out with an exposure to th...

journal_title：Medical physics

authors： Jensen TW,Randall GJ,Goldberg AJ

更新日期：1980-07-01 00:00:00

abstract：PURPOSE:To eliminate or reduce the error to Pareto optimality that arises in Pareto surface navigation when the Pareto surface is approximated by a small number of plans. METHODS:The authors propose to project the navigated plan onto the Pareto surface as a postprocessing step to the navigation. The projection attempt...

journal_title：Medical physics

authors： Bokrantz R,Miettinen K

更新日期：2015-10-01 00:00:00

abstract：PURPOSE:Traditionally, unidirectional leaf-sweeping schemes have been employed to deliver IMRT plans using the dynamic multileaf collimator (DMLC) technique. The goal of this research is to investigate the potential impact of relaxing the leaf-motion restrictions in DMLC IMRT on the beam-modulation quality and the deli...

journal_title：Medical physics

authors： Mirzapour SA,Salari E

更新日期：2018-11-01 00:00:00

abstract：:In patients with lymphoma, identification and quantification of the tumor extent on serial CT examinations is critical for assessing tumor response to therapy. In this paper, we present a computer method to automatically match and segment lymphomas in follow-up CT images. The method requires that target lymph nodes in...

journal_title：Medical physics

authors： Yan J,Zhao B,Curran S,Zelenetz A,Schwartz LH

更新日期：2007-01-01 00:00:00

abstract：:The purpose of this study is to incorporate the dosimetric effect of random patient positioning uncertainties directly into a commercial treatment planning system's IMRT plan optimization algorithm through probabilistic treatment planning (PTP) and compare coverage of this method with margin-based planning. In this wo...

journal_title：Medical physics

authors： Moore JA,Gordon JJ,Anscher MS,Siebers JV

更新日期：2009-09-01 00:00:00

abstract：PURPOSE:In photon radiotherapy, respiratory-induced target motion can be accounted for by internal target volumes (ITV) or mid-ventilation target volumes (midV) defined on the basis of four-dimensional computed tomography (4D-CT). Intrinsic limitations of these approaches can result in target volumes that are not repre...

journal_title：Medical physics

authors： Rabe M,Thieke C,Düsberg M,Neppl S,Gerum S,Reiner M,Nicolay NH,Schlemmer HP,Debus J,Dinkel J,Landry G,Parodi K,Belka C,Kurz C,Kamp F

更新日期：2020-04-01 00:00:00

abstract：PURPOSE:Spirometry exhibits baseline drift and frequent measurement errors so it cannot be used by itself to provide tidal volume-based image sorting or breathing motion modeling. Other breathing surrogates, in this study an abdominal bellows system, are drift free but do not measure tidal volume. Simultaneously using ...

journal_title：Medical physics

authors： Werner R,White B,Handels H,Lu W,Low DA

更新日期：2010-02-01 00:00:00