Pseudomyogenic hemangioendothelioma of skin, bone and soft tissue-a clinicopathological, immunohistochemical, and fluorescence in situ hybridization study.

abstract：:The aim of this study was to examine the relation between cofilin 1 expression and progression-free survival in advanced epithelial ovarian cancer. We performed quantitative reverse transcriptase polymerase chain reaction and immunohistochemical analysis in 78 patients with advanced epithelial ovarian cancer (excludin...

journal_title：Human pathology

authors： Nishimura S,Tsuda H,Kataoka F,Arao T,Nomura H,Chiyoda T,Susumu N,Nishio K,Aoki D

更新日期：2011-04-01 00:00:00

abstract：:A mixed gangliocytoma-adenoma occurring in the pituitary fossa of a patient who presented with acromegaly, galactorrhea, and headaches is described. Immunohistochemical studies demonstrated the gangliocytic portion of the tumor to be composed nearly entirely of ganglion cells enmeshed in their neuritic processes and d...

journal_title：Human pathology

authors： Kamel OW,Horoupian DS,Silverberg GD

更新日期：1989-12-01 00:00:00

abstract：:The histopathology of 72 paragangliomas originating in the head and neck region of 71 patients is presented. There were 45 carotid body, 13 vagal body, eight jugulotympanic, and three nasal paragangliomas. In addition, two arose in the larynx and one in the area of the aortic arch. Tumors occurred in four unrelated fa...

journal_title：Human pathology

authors： Lack EE,Cubilla AL,Woodruff JM

更新日期：1979-03-01 00:00:00

abstract：:Kaposi sarcoma-associated herpesvirus (KSHV) causes Kaposi sarcoma and is also associated with primary effusion lymphoma, a subset of diffuse large B-cell lymphomas, and multicentric Castleman disease. Because KSHV infection is endemic in sub-Saharan Africa, we sought to identify cases of KSHV-positive non-Hodgkin lym...

journal_title：Human pathology

authors： Engels EA,Mbulaiteye SM,Othieno E,Gomez M,Mathew S,Cesarman E,Knowles DM,Chadburn A

更新日期：2007-02-01 00:00:00

abstract：:δ-Like ligand 4 (DLL4), a ligand for the Notch family of receptors, forecasts the prognosis of several human malignancies. However, the expression and role of DLL4 in breast cancer remain largely unknown. In the present study, we first evaluated whether the overexpression of DLL4 could be used as an indicator of axill...

journal_title：Human pathology

authors： Xiao M,Yang S,Ning X,Huang Y

更新日期：2014-11-01 00:00:00

abstract：:After endoscopic resection of early gastric cancer (EGC), it is imperative to accurately determine whether follow-up surgery is indicated, since this technique is used as a first line of treatment. Herein, we developed a scoring system to indicate the risk of lymph node metastasis in submucosal EGC (smEGC), and presen...

journal_title：Human pathology

authors： Kim JY,Kim WG,Jeon TY,Kim GH,Jeong EH,Kim DH,Park DY,Lauwers GY

更新日期：2013-12-01 00:00:00

abstract：:A primary neoplasm of the proximal humerus in a 68-year-old woman was unique histologically in that it contained both malignant cartilaginous and squamous cell components. The epithelial differentiation was confirmed by the demonstration of keratin by immunohistochemical techniques and of basement membrane, tonofilame...

journal_title：Human pathology

authors： Ling LL,Steiner GC

更新日期：1986-03-01 00:00:00

abstract：:Fatty acids are implicated in tumorigenesis, but data are limited concerning endogenous fatty acid metabolism of tumor cells in adenomas and adenocarcinomas of the small intestine. The recently cloned human acyl-CoA-synthetase 5 (ACS5) is predominantly found in the small intestine and represents a key enzyme in provid...

journal_title：Human pathology

authors： Gassler N,Schneider A,Kopitz J,Schnölzer M,Obermüller N,Kartenbeck J,Otto HF,Autschbach F

更新日期：2003-10-01 00:00:00

abstract：:There is considerable interest in the role of the human wart virus in the pathogenesis of squamous cell carcinoma. Mucosal wart virus infections may produce considerable epithelial atypia and have eventuated in carcinoma in "normal" individuals in some instances. The verruciform lesions of patients with epidermodyspla...

journal_title：Human pathology

authors： Gisser SD

更新日期：1981-02-01 00:00:00

abstract：:Ground-glass hepatocytes are seen in chronic hepatitis B virus (HBV) infection and are known to harbor pre-S mutants, which are implicated in the pathogenesis of hepatocellular carcinoma (HCC). However, the association between ground-glass hepatocytes and HCC has yet to be clearly elucidated. The aim in the present st...

journal_title：Human pathology

authors： Mathai AM,Alexander J,Kuo FY,Torbenson M,Swanson PE,Yeh MM

更新日期：2013-08-01 00:00:00

abstract：:Because infants rarely suffer coronary artery thrombosis, it is mistakenly assumed that they seldom have significant ischemic myocardial injury. However, ischemic myocardial necrosis (INM) is common in the papillary muscles and subendocardium of stressed newborns and other infants. Standard dissection methods encourag...

journal_title：Human pathology

authors： Donnelly WH,Hawkins H

更新日期：1987-01-01 00:00:00

abstract：:Lymphoepithelial cysts with histological features characteristic of branchial cleft cysts have been reported to occur rarely in the thyroid gland. To our knowledge only six cases of this lesion have been reported. Since these reports brought this entity to our attention, we have noted that intrathyroidal lymphoepithel...

journal_title：Human pathology

authors： Apel RL,Asa SL,Chalvardjian A,LiVolsi VA

更新日期：1994-11-01 00:00:00

abstract：:The Mix1 homeobox-like (MIXL1) gene encodes a paired class homeobox transcription factor that is involved in embryogenesis. Previous studies have shown that the MIXL1 gene product is expressed in B- and T-cell progenitors of normal bone marrow and, in some cell lines derived from hematopoietic neoplasms. The status of...

journal_title：Human pathology

authors： Drakos E,Rassidakis GZ,Leventaki V,Guo W,Medeiros LJ,Nagarajan L

更新日期：2007-03-01 00:00:00

abstract：:Alpha-methyl CoA racemase (AMACR), a new molecular marker for prostate cancer, has been recently reported to be one of the most highly expressed genes in papillary renal cell carcinomas (RCCs). We tested the diagnostic usefulness of AMACR antibody in a series of 110 renal tumors: 53 papillary RCCs (33 type 1, 20 type ...

journal_title：Human pathology

authors： Molinié V,Balaton A,Rotman S,Mansouri D,De Pinieux I,Homsi T,Guillou L

更新日期：2006-06-01 00:00:00

abstract：:The canals of Hering (CoH), converging from the hepatic lobule onto the portal tract, connect bile canaliculi to the interlobular bile ducts, and represent the most proximal portion of the bile drainage pathway with a cholangiocyte lining. In this study we sought to ascertain whether this proximal pathway is involved ...

journal_title：Human pathology

authors： Saxena R,Hytiroglou P,Thung SN,Theise ND

更新日期：2002-10-01 00:00:00

abstract：:Pancreatic cancer (PaCA) is a deadly disease with few systemic therapeutic options. The head of the pancreas is the most innervated part and most common location of cancer. However, little is known about the contribution of the nerve-cancer interaction to facilitate pancreatic progression. To quantify PaCA axonogenesi...

journal_title：Human pathology

authors： He D,Manzoni A,Florentin D,Fisher W,Ding Y,Lee M,Ayala G

更新日期：2016-06-01 00:00:00

abstract：:Sex-determining region Y-box 2 is proposed to be a key transcription factor in embryonic stem cells. The known roles of sex-determining region Y-box 2 in development and cell differentiation suggest that it is relevant to the aberrant growth of tumor cells. Thus, sex-determining region Y-box 2 may play an important ro...

journal_title：Human pathology

authors： Zhang J,Chang DY,Mercado-Uribe I,Liu J

更新日期：2012-09-01 00:00:00

abstract：:Differentiation features and proliferation activity of 67 gastric microleiomyomas (microLMs) and 53 clinical gastrointestinal stromal tumors (GISTs) of the stomach were compared. The 67 microLMs were divided into two categories on the basis of cellularity: 53 hypocellular and 14 hypercellular types, and the 39 GISTs w...

journal_title：Human pathology

authors： Mikami T,Terada T,Nakamura K,Okayasu I

更新日期：1997-12-01 00:00:00

abstract：:Cell adhesion molecule expression has been linked to disease outcome in prostatic adenocarcinomas (PACs). We evaluated the coordinated expression of catenin-related proteins, E-cadherin, N-cadherin, and CD44s in PACs. Archival sections from 112 PACs were immunostained by an automated method (Ventana Medical Systems, T...

journal_title：Human pathology

authors： Kallakury BV,Sheehan CE,Ross JS

更新日期：2001-08-01 00:00:00

abstract：:Xanthoma is a localized collection of cholesterol-laden histiocytes that is usually idiopathic, but may be seen in patients with hyperlipidemia. We report seven cases of xanthoma involving the prostate, including one arising in a patient with mild hyperlipidemia. Prostatic xanthoma appeared as a solitary microscopic l...

journal_title：Human pathology

authors： Sebo TJ,Bostwick DG,Farrow GM,Eble JN

更新日期：1994-04-01 00:00:00

abstract：:Congenital cystic airway malformation/congenital pulmonary airway malformation (CCAM/CPAM) of the lung is a rare but well-described malformative lesion of pulmonary parenchyma characterized by the abnormal maturation of airways along with an increase in terminal respiratory structures, resulting in cysts of variable s...

journal_title：Human pathology

authors： Guo H,Cajaiba MM,Borys D,Gutierrez MC,Yee H,Drut RM,Drut R,Askin F,Reyes-Múgica M,Greco MA

更新日期：2007-12-01 00:00:00

abstract：:Immunoreactivity to LN2 and LN3, monoclonal antibodies that recognize components of the class II major histocompatibility complex, was assessed in 72 cases of non-small cell lung carcinoma (NSCLC) (32 biopsy specimens, 40 resection specimens) and 64 cases of small cell carcinoma (56 biopsy specimens, 8 resections) of ...

journal_title：Human pathology

authors： Hua ZX,Tanaka KE,Tazelaar HD,Myers J,Markowitz GS,Borczuk AC

更新日期：1998-12-01 00:00:00

abstract：:Endometrial carcinoma is the most common malignant tumor of the female genital tract in the Western world. Approximately 80% of cases are well- to moderately differentiated (endometrioid) adenocarcinomas, which are confined to the uterine corpus at diagnosis, and thus most can be cured. Conversely, high-grade (ie, cle...

journal_title：Human pathology

authors： Prat J

更新日期：2004-06-01 00:00:00

abstract：:Hepatocarcinoma-intestine-pancreas/pancreatitis-associated protein (HIP/PAP) protein, a member of the reg family, is constitutively expressed by some specialized epithelial cell subsets in the digestive tract and the pancreas. We performed a detailed analysis of the expression of HIP/PAP protein in normal digestive en...

journal_title：Human pathology

authors： Hervieu V,Christa L,Gouysse G,Bouvier R,Chayvialle JA,Bréchot C,Scoazec JY

更新日期：2006-08-01 00:00:00

abstract：:Previously used only as a screening tool, cytology now emerges as a powerful diagnostic technique, especially since the advent of the fine needle aspiration (FNA) biopsy. This article highlights the use of ancillary techniques, primarily electron microscopy (EM), and immunohistochemistry (IHC). When coupled with routi...

journal_title：Human pathology

authors： Turbat-Herrera EA,Knowles K

更新日期：1998-12-01 00:00:00

abstract：:Epithelial-to-mesenchymal transition (EMT) plays an important role in invasion and metastasis of various cancers including gliomas. EMT has also been linked to cancer stem cells and resistance to chemotherapy. An initial in-silico data mining in a published ependymoma (EPN) patient series (GSE21687) revealed up-regula...

journal_title：Human pathology

authors： Malgulwar PB,Nambirajan A,Pathak P,Rajeshwari M,Suri V,Sarkar C,Singh M,Sharma MC

更新日期：2018-12-01 00:00:00

abstract：:Virus-associated hemophagocytic syndrome (VAHS) is a nonneoplastic, generalized histiocytic proliferation with marked hemophagocytosis associated with a systemic viral infection. Histologic studies of lymph nodes usually show lymphoid depletion and histiocytic proliferation. In this report we describe the case of a pa...

journal_title：Human pathology

authors： Daum GS,Sullivan JL,Ansell J,Mulder C,Woda BA

更新日期：1987-10-01 00:00:00

abstract：:To establish whether an intramural left anterior descending coronary artery (LADA) is a simple anatomic or a singularly pathologic variant we studied 39 hearts, each with an intramural course of the LADA and no coronary artery disease, valvular derangement, cardiomyopathy, or congenital anomaly. Seventeen of the 39 he...

journal_title：Human pathology

authors： Morales AR,Romanelli R,Tate LG,Boucek RJ,de Marchena E

更新日期：1993-07-01 00:00:00

abstract：:Aquaporin 5 (AQP5) is an androgen-regulated member of a family of small hydrophobic integral transmembrane water channel proteins regulating cellular water homeostasis and growth signaling. To evaluate its clinical impact and relationship with key genomic alterations in prostate cancer, AQP5 expression was analyzed by...

journal_title：Human pathology

authors： Pust A,Kylies D,Hube-Magg C,Kluth M,Minner S,Koop C,Grob T,Graefen M,Salomon G,Tsourlakis MC,Izbicki J,Wittmer C,Huland H,Simon R,Wilczak W,Sauter G,Steurer S,Krech T,Schlomm T,Melling N

更新日期：2016-02-01 00:00:00

abstract：:Desmoplastic infantile astrocytoma/ganglioglioma (DIA/DIG) are rare primary glioneuronal tumors that comprise 0.5% to 1.0% of all intracranial tumors. While BRAF mutation is found in up to 50% of pediatric gangliogliomas, data for DIA/DIGs is limited. This study was carried out to evaluate the frequency of BRAF V600E ...

journal_title：Human pathology

authors： Chatterjee D,Garg C,Singla N,Radotra BD

更新日期：2018-10-01 00:00:00