Impaired expression of acyl-CoA-synthetase 5 in epithelial tumors of the small intestine.

abstract：:Pancreatic cancer (PaCA) is a deadly disease with few systemic therapeutic options. The head of the pancreas is the most innervated part and most common location of cancer. However, little is known about the contribution of the nerve-cancer interaction to facilitate pancreatic progression. To quantify PaCA axonogenesi...

journal_title：Human pathology

authors： He D,Manzoni A,Florentin D,Fisher W,Ding Y,Lee M,Ayala G

更新日期：2016-06-01 00:00:00

abstract：:We report three cases of follicular dendritic cell sarcoma (FDCS) showing a hitherto undescribed histological pattern consisting of nodular tumor growth associated with small B lymphocytes. FDCS tumor cells consistently showed large epithelioid features and were intermingled with small lymphocytes in the nodules in tw...

journal_title：Human pathology

authors： Lorenzi L,Lonardi S,Petrilli G,Tanda F,Bella M,Laurino L,Rossi G,Facchetti F

更新日期：2012-02-01 00:00:00

abstract：:We examined the effect of lateral spatial resolution and reader specialty on the accuracy of detection of breast cancer. The motivation for this pilot study was the need to acquire and display very large data sets in whole-specimen 3D digital breast histopathology imaging. The ultimate goal is to determine the minimum...

journal_title：Human pathology

authors： Clarke GM,Zubovits JT,Katic M,Peressotti C,Yaffe MJ

更新日期：2007-12-01 00:00:00

abstract：:Endothelial cell injury may contribute to the progression of various glomerular diseases. In the present study, we examined glomerular capillary injury in acute and chronic glomerular lesions in patients with Immunoglobulin A nephropathy (IgAN). We selected renal biopsy samples of IgAN (n = 200), and glomerular capill...

journal_title：Human pathology

authors： Kusano T,Takano H,Kang D,Nagahama K,Aoki M,Morita M,Kaneko T,Tsuruoka S,Shimizu A

更新日期：2016-03-01 00:00:00

abstract：:Congenital syphilis is often a presumptive diagnosis (based on serologies), because confirmation requires identification of Treponema pallidum in fetal/neonatal tissues or in the placenta. Placental histological features associated with congenital syphilis include the triad of enlarged hypercellular villi, proliferati...

journal_title：Human pathology

authors： Genest DR,Choi-Hong SR,Tate JE,Qureshi F,Jacques SM,Crum C

更新日期：1996-04-01 00:00:00

abstract：:Lymphoplasmacytic infiltrates in the breast, a modified skin appendage, include lymphocytic lobulitis, other nonspecific benign proliferations, and mucosa-associated lymphoid tissue (MALT)-type lymphoma. Distinguishing these entities, all of which may be B-cell rich and may have associated sclerosis, can be difficult....

journal_title：Human pathology

authors： Berg AN,Soma L,Clark BZ,Swerdlow SH,Roth CG

更新日期：2015-08-01 00:00:00

abstract：:Perineural invasion is a histologic feature usually diagnostic of invasion in malignancies. In the breast, however, it has been associated with benign lesions such as sclerosing adenosis (SA), complex sclerosing lesion/radial scar (CSL/RS), and ductal carcinoma in situ (DCIS). This article describes perineural invasio...

journal_title：Human pathology

authors： Gobbi H,Jensen RA,Simpson JF,Olson SJ,Page DL

更新日期：2001-08-01 00:00:00

abstract：:The national decline in hospital autopsy cases negatively impacts physician education and medical quality control to an unknown degree. The current non-medicolegal autopsy rate is less than 5% of hospital deaths. This study compares internal medicine and pathology resident physician perceptions of the autopsy, includi...

journal_title：Human pathology

authors： Hull MJ,Nazarian RM,Wheeler AE,Black-Schaffer WS,Mark EJ

更新日期：2007-02-01 00:00:00

abstract：:Human papillomavirus-related oropharyngeal squamous cell carcinoma has a unique biology and improved prognosis. A new focus is to identify prognostic biomarkers specifically in this human papillomavirus-positive cohort. We analyzed cyclin D1 immunostaining on a tissue microarray of patients with known clinical follow-...

journal_title：Human pathology

authors： Scantlebury JB,Luo J,Thorstad WL,El-Mofty SK,Lewis JS Jr

更新日期：2013-08-01 00:00:00

abstract：:Pathological demonstration of varicella infection in first trimester aborted tissue is reported. A 24-year-old primigravida manifested chickenpox infection about 38 days after her last menstrual period or at 24 days age of the embryo. The conceptus survived another 4 to 5 weeks. The macerated embryo and placental tiss...

journal_title：Human pathology

authors： Oyer CE,Cai R,Coughlin JJ,Singer DB

更新日期：1998-01-01 00:00:00

abstract：:This report concerns a young woman who, after taking a contraceptive preparation orally for three years, developed the Budd-Chiari syndrome as the result of a widespread chronic obliterative process involving the intrahepatic efferent venous system. Her prolonged course, which failed to respond to an end-to-side porta...

journal_title：Human pathology

authors： Alpert LI

更新日期：1976-11-01 00:00:00

abstract：:Implementation of Grade Groups (GrGrs) has been widely accepted for reporting prostate cancer grade since the 2014 International Society of Urological Pathology consensus meeting. Despite their undisputed value for risk stratification, some GrGr are, a priori, quite heterogeneous in that they contain multiple Gleason ...

journal_title：Human pathology

authors： Acosta AM,Taplin ME,Mata DA,D'Amico AV,Hirsch MS

更新日期：2020-05-01 00:00:00

abstract：:A 3-year-old boy with congenital nemaline myopathy had generalized muscle weakness and hypotonia since birth. He developed cardiac symptoms at 2 years of age and died from congestive heart failure. At autopsy, the heart was markedly dilated, involving both ventricles. Rod bodies were recognized not only in skeletal mu...

journal_title：Human pathology

authors： Ishibashi-Ueda H,Imakita M,Yutani C,Takahashi S,Yazawa K,Kamiya T,Nonaka I

更新日期：1990-01-01 00:00:00

abstract：:A small number (4% to 6%) of primary malignant lymphomas arising in the intestines express the EBV genome. However, in these tumors, the viral genotype and the role of tumor suppressor gene p53 have not been investigated. We sought to determine what genotype of EBV is frequently involved and whether the expression of ...

journal_title：Human pathology

authors： Kim YS,Kim JB,Kang YK,Nam ES,Park SH,Kim I

更新日期：1999-10-01 00:00:00

abstract：:Twenty-two consecutive cases of adenoma in acromegalic patients were studied immunohistochemically. All the tumors contained prolactin (PRL)-reactive cells (3% to 53% of the total number of tumor cells) as well as growth hormone (GH)-reactive cells (4% to 74% of the total number of tumor cells). All acromegalic cases ...

journal_title：Human pathology

authors： Furuhata S,Kameya T,Otani M,Toya S

更新日期：1993-01-01 00:00:00

abstract：:Overexpression of mitotic arrest deficient 2 (MAD2) and/or cell division cycle 20 (CDC20) in the spindle assembly checkpoint leads to chromosomal instability and aneuploidy. Cell-in-cell (CIC) structures are formed by the process where cancer or immune cells are internalized into adjacent host cancer cells. Here, we i...

journal_title：Human pathology

authors： Kim Y,Choi JW,Lee JH,Kim YS

更新日期：2019-03-01 00:00:00

abstract：:Pleomorphic adenomas of the breast (PAB) are uncommon tumors. We studied the clinicopathologic features of 10 cases of PAB, seven of which were assessed immunohistochemically. Nine patients were women, with a median age at diagnosis of 65 years. Eight patients presented with a palpable mass; two had a nipple discharge...

journal_title：Human pathology

authors： Diaz NM,McDivitt RW,Wick MR

更新日期：1991-12-01 00:00:00

abstract：:A digoxigenin-tailed, synthetic oligodeoxynucleotide was used to detect genomic hepatitis delta virus (HDV) RNA in formalin-fixed, paraffin-embedded liver sections by a nonisotopic in situ hybridization (NISH) procedure. Twenty-three liver samples from chronically HDV-infected patients were studied. Eight liver specim...

journal_title：Human pathology

authors： Pacchioni D,Negro F,Chiaberge E,Rizzetto M,Bonino F,Bussolati G

更新日期：1992-05-01 00:00:00

abstract：:A case of apocrine carcinoma of the breast with psammoma bodies is described in a 69 year old man. The report emphasizes the rarity of this lesion and supports currently held beliefs about the formation of psammoma bodies. ...

journal_title：Human pathology

authors： Bryant J

更新日期：1981-08-01 00:00:00

abstract：:One hundred six liver biopsy specimens from 34 orthotopic liver transplant (OLT) patients were examined and the histologic findings correlated with the clinical course of the patients to determine if specific morphologic patterns were associated with specific causes of acute allograft dysfunction. The principle causes...

journal_title：Human pathology

authors： Ray RA,Lewin KJ,Colonna J,Goldstein LI,Busuttil RW

更新日期：1988-07-01 00:00:00

abstract：:The shortage of pathologists is being created by a combination of three factors: inadequate trainee recruitment, high trainee attrition, and accelerating practitioner attrition. The current report provides comprehensive data on the first two factors. The third factor is, by every estimate, likely to become worse over ...

journal_title：Human pathology

authors： Vance RP,Prichard RW,Smith RD

更新日期：1991-11-01 00:00:00

abstract：:The intraoperative diagnosis of pulmonary neuroendocrine tumors can be difficult. Frozen section diagnosis was requested on 87 neuroendocrine tumors including 58 typical carcinoids, 8 atypical carcinoids, 18 large cell neuroendocrine carcinomas, and 3 small cell carcinomas from 2405 patients that underwent frozen sect...

journal_title：Human pathology

authors： Gupta R,Dastane A,McKenna RJ Jr,Marchevsky AM

更新日期：2009-01-01 00:00:00

abstract：:In a large-scale analysis of gene expression in pancreatic cancer, we isolated the homologue of the mouse Rab20. The mouse protein was previously identified during a search for novel Rab proteins, a family of small GTP-binding proteins involved in the regulation of intracellular vesicular transport. The Rab20 protein ...

journal_title：Human pathology

authors： Amillet JM,Ferbus D,Real FX,Antony C,Muleris M,Gress TM,Goubin G

更新日期：2006-03-01 00:00:00

abstract：:Histopathologic lesions in the central nervous system (CNS) of 400 autopsy cases of the acquired immunodeficiency syndrome (AIDS) collected from 1982 to 1990 were studied. Lesions most closely associated with human immunodeficiency virus (HIV) infection in the CNS (perivascular macrophages, nodular encephalomyelitis, ...

journal_title：Human pathology

authors： Rhodes RH

更新日期：1993-11-01 00:00:00

abstract：:The use of interleukin-2 (IL-2), either alone or in combination with lymphokine-activated killer cells, tumor infiltrating lymphocytes, or other immunotherapeutic agents has added a new list of alternatives to conventional antineoplastic regimens. Little information is available about the pathologic changes occurring ...

journal_title：Human pathology

authors： Kragel AH,Travis WD,Feinberg L,Pittaluga S,Striker LM,Roberts WC,Lotze MT,Yang JJ,Rosenberg SA

更新日期：1990-05-01 00:00:00

abstract：:Massive chronic intervillositis (MCI) is an unusual placental lesion associated with poor fetal growth and adverse pregnancy outcome; it has not previously been associated with spontaneous abortion or recurrent pregnancy loss. This article reports a patient who had 10 spontaneous abortions with repetitious massive chr...

journal_title：Human pathology

authors： Doss BJ,Greene MF,Hill J,Heffner LJ,Bieber FR,Genest DR

更新日期：1995-11-01 00:00:00

abstract：:Five hundred eighty renal biopsies from a pool of 27850 archived cases were identified in which a myoglobin stain was performed because of atypical casts. Two hundred and thirty-eight (41%) of these biopsies were found to be positive for myoglobin casts. The morphology of the myoglobin casts ranged from light, almost ...

journal_title：Human pathology

authors： Liapis H,Boils C,Hennigar R,Silva F

更新日期：2016-08-01 00:00:00

abstract：:Paracoccidioidomycosis is a systemic mycosis with a geographic distribution that is limited to Central and South America; Brazil has the highest number of cases. Severe disseminated disease caused by paracoccidioidomycosis was observed in acquired immunodeficiency syndrome patients who live or have resided in endemic ...

journal_title：Human pathology

authors： de Freitas RS,Dantas KC,Garcia RS,Magri MM,de Andrade HF Jr

更新日期：2010-09-01 00:00:00

abstract：:The purpose of this study was to objectively investigate β-catenin and LEF1 abundance, subcellular localization, and colocalization across benign and staged prostate cancer (PCa) specimens. A tissue microarray containing tumor-adjacent histologically benign prostate tissue (BPT; n = 48 patients), high-grade prostatic ...

journal_title：Human pathology

authors： Bauman TM,Vezina CM,Ricke EA,Halberg RB,Huang W,Peterson RE,Ricke WA

更新日期：2016-05-01 00:00:00

abstract：:Patients undergoing treatment of acute lymphoblastic leukemia are at risk for fungal infections including disseminated candidiasis. We describe a case of systemic Candida albicans infection associated with life-threatening gastrointestinal hemorrhage due to unusual necrotizing vasculitis involving the gastrointestinal...

journal_title：Human pathology

authors： Sargent J,O'Marcaigh A,Smith O,Butler K,Gavin P,O'Sullivan M

更新日期：2010-04-01 00:00:00