To Cut or Not to Cut: Discovery of a Novel Regulator of DNA Break Resection.

Abstract:

:Nucleolytic resection of DNA double-strand breaks is the crucial first step in their repair via homologous recombination. New findings by Tkáč et al. (2016) published in this issue of Molecular Cell identify HELB as a novel, cell-cycle-specific negative regulator of DNA end resection.

journal_name

Mol Cell

journal_title

Molecular cell

authors

Daley JM,Sung P

doi

10.1016/j.molcel.2016.01.022

subject

Has Abstract

pub_date

2016-02-04 00:00:00

pages

325-326

issue

3

eissn

1097-2765

issn

1097-4164

pii

S1097-2765(16)00049-6

journal_volume

61

pub_type

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