Knowledge, attitude and awareness among healthcare professionals about influenza vaccination in Peshawar, Pakistan.

abstract：:Seasonal influenza epidemics represent a substantial public health burden, causing significant morbidity and mortality. Influenza in humans can be caused by influenza type A and type B viruses, and although influenza A is responsible for the majority of seasonal influenza infections, influenza B disease is common in c...

journal_title：Vaccine

authors： Belshe RB

更新日期：2010-09-07 00:00:00

abstract：:A new strategy for designing synthetic vaccines is presented. In this approach synthetic peptides are conformationally restricted by replacing putative hydrogen bonds with covalent mimics. The chemistry for substituting a hydrazone-ethane link (N-N = CH-CH2-CH2) for an (i + 4)----i hydrogen bond in a pentapeptide with...

journal_title：Vaccine

authors： Satterthwait AC,Arrhenius T,Hagopian RA,Zavala F,Nussenzweig V,Lerner RA

更新日期：1988-04-01 00:00:00

abstract：:The chloroplast genetic engineering offers a number of unique advantages including high level of transgene expression, multi-gene expression in single transformation event and transgene containment due to maternal inheritance. Hyper-expression of vaccine antigens or therapeutic proteins in transgenic chloroplasts (lea...

journal_title：Vaccine

authors： Daniell H,Chebolu S,Kumar S,Singleton M,Falconer R

更新日期：2005-03-07 00:00:00

abstract：:Enterotoxigenic E. coli (ETEC) are an important cause of diarrhea in developing countries, especially among indigenous children and travelers. In this randomized, double-blind, placebo-controlled trial, a live, attenuated CS1/CS3 ETEC strain, PTL-003, was tested as a potential vaccine strain. Thirty-three subjects dra...

journal_title：Vaccine

authors： McKenzie R,Darsley M,Thomas N,Randall R,Carpenter C,Forbes E,Finucane M,Sack RB,Hall E,Bourgeois AL

更新日期：2008-08-26 00:00:00

abstract：:A post hoc analysis was performed using combined data from two Phase I tolerability/immunogenicity studies of monovalent human papillomavirus type 11 (HPV11) or HPV16 L1 virus-like particle (VLP) vaccines. The goal was to determine if the HPV16 L1 VLP vaccine protected against HPV16 infection. Vaccine or placebo was g...

journal_title：Vaccine

authors： Brown DR,Fife KH,Wheeler CM,Koutsky LA,Lupinacci LM,Railkar R,Suhr G,Barr E,Dicello A,Li W,Smith JF,Tadesse A,Jansen KU

更新日期：2004-07-29 00:00:00

abstract：:Since 1996, the scientific community has become aware of 14 reports of yellow fever vaccine (YEL)-associated viscerotropic disease (YEL-AVD) cases and four reports of YEL-associated neurotropic disease (YEL-AND) worldwide, changing our understanding of the risks of the vaccine. Based on 722 adverse event reports after...

journal_title：Vaccine

authors： Khromava AY,Eidex RB,Weld LH,Kohl KS,Bradshaw RD,Chen RT,Cetron MS,Yellow Fever Vaccine Safety Working Group.

更新日期：2005-05-09 00:00:00

abstract：:This study compared the safety and immunogenicity of DTaP₅-IPV-Hib vaccine (followed by monovalent hepatitis B vaccine [HBV]) and DTaP₃-HBV-IPV/Hib vaccines, both coadministered with PCV7, as a fourth-dose booster in toddlers 11-18 months who had a hexavalent vaccine primary series. The fever rate within 4 days of DTa...

journal_title：Vaccine

authors： Berner R,Boisnard F,Thomas S,Mwawasi G,Reynolds D

更新日期：2012-07-27 00:00:00

abstract：:Cattle produce specific serum antibody mainly of the IgG1 isotype in response to infection with the liver fluke, Fasciola hepatica. In these animals a positive correlation between fluke-specific serum IgG1 levels and fluke-burden in non-immunized infected animals was observed. In contrast, immunization of cattle with ...

journal_title：Vaccine

authors： Mulcahy G,O'Connor F,McGonigle S,Dowd A,Clery DG,Andrews SJ,Dalton JP

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND:In 2017, measles elimination was verified in Bhutan, and the country appears to have sufficiently high vaccination coverage to achieve rubella elimination. However, a measles and rubella serosurvey was conducted to find if any hidden immunity gaps existed that could threaten Bhutan's elimination status. MET...

journal_title：Vaccine

authors： Wangchuk S,Nogareda F,Tshering N,Khandu L,Pelden S,Wannemuehler K,Wangdi S,Wangchuk U,Mulders M,Tamang T,Patel MK

更新日期：2019-10-08 00:00:00

abstract：:The ability to protect mice against respiratory infections with virulent Francisella tularensis has been problematic and the role of antibody-versus-cell-mediated immunity controversial. In this study, we tested the hypothesis that protective immunity can develop in mice that were given antibiotic therapy following in...

journal_title：Vaccine

authors： Klimpel GR,Eaves-Pyles T,Moen ST,Taormina J,Peterson JW,Chopra AK,Niesel DW,Carness P,Haithcoat JL,Kirtley M,Nasr AB

更新日期：2008-12-09 00:00:00

abstract：:T lymphocytes play a central role in the generation of a protective immune response in many microbial infections. After immunization, dendritic cells take up microbial antigens and traffic to draining lymph nodes where they present processed antigens to naïve T cells. These naïve T cells are stimulated to proliferate ...

journal_title：Vaccine

authors： Esser MT,Marchese RD,Kierstead LS,Tussey LG,Wang F,Chirmule N,Washabaugh MW

更新日期：2003-01-17 00:00:00

abstract：:This report provides an overview of methods used to conduct systematic reviews for the US Food and Drug Administration (FDA) Mini-Sentinel project, which is designed to inform the development of safety monitoring tools for FDA-regulated products including vaccines. The objective of these reviews was to summarize the l...

journal_title：Vaccine

authors： McPheeters ML,Sathe NA,Jerome RN,Carnahan RM

更新日期：2013-12-30 00:00:00

abstract：:Five week old, commercially available large white pigs were vaccinated with either a single dose or two doses of a recombinant porcine adenovirus expressing the glycoprotein D gene from pseudorabies virus (PRV). Pigs were monitored for the development of serum neutralizing antibodies to PRV and challenged 3 weeks afte...

journal_title：Vaccine

authors： Hammond JM,Jansen ES,Morrissy CJ,van der Heide B,Goff WV,Williamson MM,Hooper PT,Babiuk LA,Tikoo SK,Johnson MA

更新日期：2001-06-14 00:00:00

abstract：BACKGROUND:It has been assumed that measles infection may be associated with persistent immune suppression and long-term excess mortality. However, few community studies of mortality after measles infection have been carried out. We examined long-term mortality for measles cases, sub-clinical measles cases, and uninfec...

journal_title：Vaccine

authors： Aaby P,Simondon F,Samb B,Cisse B,Jensen H,Lisse IM,Soumaré M,Whittle H

更新日期：2002-11-22 00:00:00

abstract：:T-lymphocyte responses to influenza vaccination were measured in healthy young and older adult volunteers. All participants were vaccinated with the 1995-96 trivalent influenza vaccine. Cytokine and granzyme B levels were measured in peripheral blood mononuclear cells (PBMC) cultures after virus stimulation, prior to ...

journal_title：Vaccine

authors： McElhaney JE,Upshaw CM,Hooton JW,Lechelt KE,Meneilly GS

更新日期：1998-11-01 00:00:00

abstract：:The prospective studies available today confirm the experience gained from several retrospective studies that TBE is a disease with a severe acute clinical course and considerable long-term morbidity. A defined post-encephalitic TBE syndrome exists, causing long-lasting morbidity that often affects the quality of life...

journal_title：Vaccine

authors： Haglund M,Günther G

更新日期：2003-04-01 00:00:00

abstract：:In this study, in vivo electroporation of a DNA vaccine adjuvanted with plasmids encoding different cytokines was investigated in large animals. Sheep were injected intramuscularly with a DNA vaccine encoding an antigen of Haemonchus contortus (pNPA) and plasmids encoding different cytokines followed by in vivo electr...

journal_title：Vaccine

authors： Yen HH,Scheerlinck JP

更新日期：2007-03-30 00:00:00

abstract：AIMS:The study was designed to evaluate a novel cationic lipid DNA adjuvant (N3) and its function for HIV-1gp160/rev DNA plasmid delivered intranasally. The primary N3/HIV-DNA plasmid immunizations were boosted intranasally with a gp41 peptide in a anionic L3 adjuvant. This novel prime-boost strategy of mucosal immuniz...

journal_title：Vaccine

authors： Hinkula J,Devito C,Zuber B,Benthin R,Ferreira D,Wahren B,Schröder U

更新日期：2006-05-22 00:00:00

abstract：:Since inactivated influenza vaccines mainly confer protective immunity by inducing strain-specific antibodies to the viral hemagglutinin, these vaccines only afford protection against infection with antigenically matching influenza virus strains. Due to the continuous emergence of antigenic drift variants of seasonal ...

journal_title：Vaccine

authors： Altenburg AF,Rimmelzwaan GF,de Vries RD

更新日期：2015-01-15 00:00:00

abstract：BACKGROUND:British Columbia (BC) introduced a school-based HPV vaccine program in September 2008. As part of the HPV vaccine program evaluation, we determined the type-specific HPV prevalence in a population-based sample of women presenting for routine cervical cancer screening in the province. METHODS:From June 2010 ...

journal_title：Vaccine

authors： Ogilvie GS,Cook DA,Taylor DL,Rank C,Kan L,Yu A,Mei W,van Niekerk DJ,Coldman AJ,Krajden M

更新日期：2013-02-04 00:00:00

abstract：:Clinical and post-licensure data have demonstrated that AS03-adjuvanted inactivated split virion vaccines, many with reduced antigen content, are effective against influenza infection. The objective of this review is to provide a comprehensive assessment of the safety of trivalent seasonal, monovalent pre-pandemic and...

journal_title：Vaccine

authors： Cohet C,van der Most R,Bauchau V,Bekkat-Berkani R,Doherty TM,Schuind A,Tavares Da Silva F,Rappuoli R,Garçon N,Innis BL

更新日期：2019-05-21 00:00:00

abstract：:Two double-blind randomised controlled studies (phase I and I/II) were performed to assess for the first time the safety and immunogenicity of a recombinant subunit gp350 Epstein-Barr virus (EBV) vaccine in 148 healthy adult volunteers. All candidate vaccine formulations had a good safety profile and were well tolerat...

journal_title：Vaccine

authors： Moutschen M,Léonard P,Sokal EM,Smets F,Haumont M,Mazzu P,Bollen A,Denamur F,Peeters P,Dubin G,Denis M

更新日期：2007-06-11 00:00:00

abstract：:In Italy vaccination against human papillomavirus (HPV) was introduced in the national immunization programme in 2007; the primary target for this vaccination is 11-year-old females, whereas vaccination for older age groups is still a matter of debate. This project was carried out in the period 2007-2009 to estimate t...

journal_title：Vaccine

authors： Giambi C,Donati S,Declich S,Salmaso S,Ciofi Degli Atti ML,Alibrandi MP,Brezzi S,Carozzi F,Collina N,Franchi D,Lattanzi A,Meda M,Minna MC,Nannini R,Scherillo I,Bella A,PreGio Working Group.

更新日期：2011-10-26 00:00:00

abstract：:A safety requirement for live vaccines is investigating possible shedding in recipients since the presence of replication competent vaccine in secretions could result in direct and indirect horizontal transmission. This is especially relevant for oral rabies vaccine baits that are deliberately distributed into the env...

journal_title：Vaccine

authors： Vos A,Freuling C,Ortmann S,Kretzschmar A,Mayer D,Schliephake A,Müller T

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Alternative methods for influenza vaccine production are needed to ensure adequate supplies. METHODS:Healthy adults 50-64 years were assigned randomly to receive one intramuscular injection of trivalent recombinant hemagglutinin (rHA) or U.S. licensed trivalent inactivated vaccine (TIV) containing H1, H3 an...

journal_title：Vaccine

authors： Baxter R,Patriarca PA,Ensor K,Izikson R,Goldenthal KL,Cox MM

更新日期：2011-03-09 00:00:00

abstract：:The liver fluke Fasciola hepatica contributes to great economic and health losses in the cattle industry in many countries, including Poland. Unfortunately, no vaccine against fasciolosis is commercially available. We have designed a DNA vaccine and tested it in rats. Groups of male or female rats received one intramu...

journal_title：Vaccine

authors： Kofta W,Mieszczanek J,Płucienniczak G,Wedrychowicz H

更新日期：2000-07-01 00:00:00

abstract：:In 2006 the United States experienced the largest nationwide mumps epidemic in 20 years, primarily affecting college dormitory residents. Unexpected elements of the outbreak included very abrupt time course (75% of cases occurred within 90 days), geographic focality (85% of cases occurred in eight rural Midwestern sta...

journal_title：Vaccine

authors： Barskey AE,Glasser JW,LeBaron CW

更新日期：2009-10-19 00:00:00

abstract：:Mouse brain-derived, purified inactivated Japanese encephalitis vaccine (MB JEV) has been locally produced and introduced into Thai National Immunization Program (NIP) since 1990. However, MB JEV effectiveness has been concerned, since 30-40% of JE cases received JE vaccines were recently reported in two descriptive s...

journal_title：Vaccine

authors： Muangchana C,Henprasertthae N,Nurach K,Theppang K,Yoocharoen P,Varinsathien P,Techathawat S,Sanohsieng S,Anantapreecha S

更新日期：2012-01-05 00:00:00

abstract：OBJECTIVE:The study objectives were to evaluate injection practices in China in the post GAVI project era and provide guidance for policy makers to update national standards for injection practices and further improve vaccination services. METHODS:We conducted a national stratified, cross-sectional survey in October 2...

journal_title：Vaccine

authors： Wu Z,Cui F,Chen Y,Miao N,Gong X,Luo H,Wang F,Zheng H,Kane M,Hadler SC,Hutin YJ,Liang X,Yang W

更新日期：2013-12-27 00:00:00

abstract：:Pneumococcal type 1 pilus proteins have been proposed as potential vaccine candidates. Following conjugate pneumococcal vaccination, the prevalence of the pneumococcal type 1 pilus declined dramatically, a decline associated with the elimination of vaccine-type (VT) strains. Here we show that between 2004 and 2007, th...

journal_title：Vaccine

authors： Regev-Yochay G,Hanage WP,Trzcinski K,Rifas-Shiman SL,Lee G,Bessolo A,Huang SS,Pelton SI,McAdam AJ,Finkelstein JA,Lipsitch M,Malley R

更新日期：2010-07-05 00:00:00