Abstract：
:The introduction of chemotherapeutic agents directly into the proper hepatic artery via an indwelling catheter results in perfusion of the gallbladder, because the cystic artery is usually a branch of the right hepatic artery. Five gallbladders, removed two to 16 months after insertion of permanently implanted Infusaid model 400 pumps, were examined. All of the gallbladders had significant arteritis, with narrowing or occlusion of lumina or necrosis of vessel walls. Fibrosis of the gallbladder wall was also a constant finding. Nuclear atypia of mucosal epithelium and connective tissue was common. Varying degrees of acute and chronic inflammation were present. These abnormalities may have a radiomimetic and direct irritant pathogenesis.
journal_name
Hum Patholjournal_title
Human pathologyauthors
Marymont JV,Dakhil SR,Travers H,Housholder DFdoi
10.1016/s0046-8177(85)80275-6subject
Has Abstractpub_date
1985-10-01 00:00:00pages
986-90issue
10eissn
0046-8177issn
1532-8392pii
S0046-8177(85)80275-6journal_volume
16pub_type
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