Abstract：
:The profile of endogenous opioid peptides in the peptide-rich fraction obtained from a homogenate of an ACTH-secreting human pituitary tumor is presented. Gradient RP-HPLC is used to separate the mixture into peptide constituents. A preparation of opioid receptors is used in a radioreceptor assay with ethorphine - a relatively non-specific ligand that is used as a screen because it interacts with mu, sigma, and delta receptors - as the HPLC detector to detect a range of peptides that derive from proenkephalin A and POMC.
journal_name
Life Scijournal_title
Life sciencesauthors
Desiderio DM,Cezayirli RC,Fridland G,Robertson JT,Sacks Hdoi
10.1016/0024-3205(85)90225-5subject
Has Abstractpub_date
1985-11-11 00:00:00pages
1823-8issue
19eissn
0024-3205issn
1879-0631pii
0024-3205(85)90225-5journal_volume
37pub_type
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