A single regulatory region modulates both cis activation and trans activation of the herpes simplex virus VP5 promoter in transient-expression assays in vivo.

abstract：:Human influenza viruses are more efficiently isolated by inoculating patient samples into the amniotic rather than the allantoic cavity of embryonated chicken eggs. This type of cultivation selects virus variants with mutations around the hemagglutinin (HA) receptor binding site. To understand the molecular basis of t...

journal_title：Journal of virology

authors： Ito T,Suzuki Y,Takada A,Kawamoto A,Otsuki K,Masuda H,Yamada M,Suzuki T,Kida H,Kawaoka Y

更新日期：1997-04-01 00:00:00

abstract：:A panel of monoclonal antibodies that recognize the two major glycoproteins of bovine viral diarrhea virus (BDV) was used to evaluate the antigenic relationship between cytopathic (CP) and noncytopathic (NCP) viruses isolated from cattle dead or dying from fatal BDV infections. Various unrelated BDV isolates were init...

journal_title：Journal of virology

authors： Corapi WV,Donis RO,Dubovi EJ

更新日期：1988-08-01 00:00:00

abstract：:The temporal sequence of coronavirus plus-strand and minus-strand RNA synthesis was determined in 17CL1 cells infected with the A59 strain of mouse hepatitis virus (MHV). MHV-induced fusion was prevented by keeping the pH of the medium below pH 6.8. This had no effect on the MHV replication cycle, but gave 5- to 10-fo...

journal_title：Journal of virology

authors： Sawicki SG,Sawicki DL

更新日期：1986-01-01 00:00:00

abstract：:RmI, a circular chimera made of the polyomavirus (Py) genome with an insertion of mouse DNA (Ins), effectively undergoes intramolecular recombination in normal mouse cells, as indicated by the conversion of cloned RmI (RmIc) into unit-length Py DNA in transfected cultures. To follow the fate of the cellular component ...

journal_title：Journal of virology

authors： Piché A,Bourgaux P

更新日期：1987-03-01 00:00:00

abstract：UNLABELLED:Mumps virus (MuV), a paramyxovirus containing a negative-sense nonsegmented RNA genome, is a human pathogen that causes an acute infection with symptoms ranging from parotitis to mild meningitis and severe encephalitis. Vaccination against mumps virus has been effective in reducing mumps cases. However, rece...

journal_title：Journal of virology

authors： Pickar A,Xu P,Elson A,Li Z,Zengel J,He B

更新日期：2014-04-01 00:00:00

abstract：:Marek's disease herpesvirus A antigen (MDHV-A) was identified as a 61,000- to 65,000-dalton glycoprotein by sodium dodecyl sulfate-polyacrylamide gel electrophoresis after immunoprecipitation from the culture medium of both [35S]methionine- and [14C]glucosamine-labeled infected cells by specific rabbit serum directed ...

journal_title：Journal of virology

authors： Glaubiger C,Nazerian K,Velicer LF

更新日期：1983-03-01 00:00:00

abstract：:Hepatitis C virus (HCV) exploits cellular proteins to facilitate viral propagation. To identify the cellular factors involved in the HCV life cycle, we previously performed protein microarray assays using either HCV nonstructural 5A (NS5A) protein or core protein as a probe. Interestingly, cellular cortactin strongly ...

journal_title：Journal of virology

authors： Nguyen LP,Nguyen TTT,Nguyen HC,Pham HT,Han KM,Choi DH,Park EM,Kang SM,Tark D,Lim YS,Hwang SB

更新日期：2020-09-15 00:00:00

abstract：:The major adenovirus (Ad) capsid proteins hexon, penton, and fiber influence the efficiency and tropism of gene transduction by Ad vectors. Fiber is the high-affinity receptor binding protein that serves to mediate cell attachment in vitro when using coxsackie-adenovirus receptor (CAR)-containing cell lines. This cont...

journal_title：Journal of virology

authors： Schoggins JW,Nociari M,Philpott N,Falck-Pedersen E

更新日期：2005-09-01 00:00:00

abstract：:Two essential gene products of herpes simplex virus type 1, the viral DNA polymerase (pol) and UL42, its accessory protein, physically and functionally interact to form the core of the viral DNA replication complex. Understanding this essential interaction would provide a basis from which to develop novel anti-herpesv...

journal_title：Journal of virology

authors： Monahan SJ,Barlam TF,Crumpacker CS,Parris DS

更新日期：1993-10-01 00:00:00

abstract：UNLABELLED:Susceptibility or resistance to prion infection in humans and animals depends on single prion protein (PrP) amino acid substitutions in the host, but the agent's modulating role has not been well investigated. Compared to disease incubation times in wild-type homozygous ARQ/ARQ (where each triplet represents...

journal_title：Journal of virology

authors： Langeveld JP,Jacobs JG,Hunter N,van Keulen LJ,Lantier F,van Zijderveld FG,Bossers A

更新日期：2015-10-28 00:00:00

abstract：:Superinfection of Corynebacterium diphtheriae C7(beta) by heteroimmune phage gamma is productive, whereas superinfection by gamma-bin mutants is for the most part nonproductive. Exclusion of gamma-bin phage occurred after its DNA had penetrated and was partially expressed in the heteroimmune lysogen. All of the infect...

journal_title：Journal of virology

authors： Groman NB,Rabin M

更新日期：1980-11-01 00:00:00

abstract：:The US3 protein kinase of herpes simplex virus 1 blocks apoptosis induced by replication-incompetent virus mutants, proapoptotic members of the Bcl-2 family of proteins, and by a variety of other agents that act at the premitochondrial level in the proapoptotic cascade. To define the role of US3 in blocking apoptosis ...

journal_title：Journal of virology

authors： Benetti L,Roizman B

更新日期：2007-10-01 00:00:00

abstract：:The genome of infectious hematopoietic necrosis virus (IHNV), a salmonid novirhabdovirus, has been engineered to modify the gene order and to evaluate the impact on a possible attenuation of the virus in vitro and in vivo By reverse genetics, eight recombinant IHNVs (rIHNVs), termed NxGy according to the respective po...

journal_title：Journal of virology

authors： Rouxel RN,Tafalla C,Mérour E,Leal E,Biacchesi S,Brémont M

更新日期：2016-11-14 00:00:00

abstract：:The nef gene contributes to the replication of primate lentiviruses by altering the trafficking of cellular proteins involved in adaptive immunity (class I and II major histocompatibility complex [MHC]) and viral transmission (CD4 and DC-SIGN). A conserved acidic leucine-based sequence (E(160)xxxLL) within human immun...

journal_title：Journal of virology

authors： Coleman SH,Madrid R,Van Damme N,Mitchell RS,Bouchet J,Servant C,Pillai S,Benichou S,Guatelli JC

更新日期：2006-02-01 00:00:00

abstract：:Human herpesviruses encode posttranscriptional activators that are believed to up-regulate viral replication by facilitating early and late gene expression. We have reported previously that the Epstein-Barr virus protein EB2 (also called M or SM) promotes nuclear export of RNAs that are poor substrates for spliceosome...

journal_title：Journal of virology

authors： Farjot G,Buisson M,Duc Dodon M,Gazzolo L,Sergeant A,Mikaelian I

更新日期：2000-07-01 00:00:00

abstract：:A restriction map was constructed for the 17.5-kilobase SalI C fragment of SP82 DNA. Unfractionated SP82 DNA, the SalI C fragment, and restriction fragments derived from SalI-C were used as templates for in vitro synthesis by the Bacillus subtilis RNA polymerase, and the resulting transcripts were analyzed by gel elec...

journal_title：Journal of virology

authors： Panganiban AT,Whiteley HR

更新日期：1981-01-01 00:00:00

abstract：:A host-mediated RNA-editing event allows hepatitis delta virus (HDV) to express two essential proteins, the small delta antigen (HDAg-S) and the large delta antigen (HDAg-L), from a single open reading frame. One or several members of the ADAR (adenosine deaminases that act on RNA) family are thought to convert the ad...

journal_title：Journal of virology

authors： Sato S,Wong SK,Lazinski DW

更新日期：2001-09-01 00:00:00

abstract：:Temperature-sensitive (ts) mutants of the T4 phage rII gene were islated and used in temperature shift experiments that revelaed two different expressions for the normal rII (rII+) gene function in vivo: (i) an early expression (0 to 12 min postinfection at 30 C) that prevents restriction of T4 growth in Escherichia c...

journal_title：Journal of virology

authors： Heere LJ,Karam JD

更新日期：1975-10-01 00:00:00

abstract：:Monoclonal antibodies to varicella-zoster virus were used to study viral glycoproteins by immunoprecipitation and sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Based on the viral glycoproteins immunoprecipitated, the five monoclonal antibodies fell into three groups. Two antibodies, 4B7 and 8G9 (group 1),...

journal_title：Journal of virology

authors： Forghani B,Dupuis KW,Schmidt NJ

更新日期：1984-10-01 00:00:00

abstract：:Experiments were conducted to investigate the roles of Marek's disease virus serotype 1 (MDV-1) major tegument proteins VP11/12, VP13/14, VP16, and VP22 in viral growth in cultured cells. Based on a bacterial artificial chromosome clone of MDV-1 (BAC20), mutant viruses were constructed in which the MDV-1 homologs of U...

journal_title：Journal of virology

authors： Dorange F,Tischer BK,Vautherot JF,Osterrieder N

更新日期：2002-02-01 00:00:00

abstract：:Epstein-Barr virus (EBV) undergoes latent and lytic replication cycles, and its reactivation from latency to lytic replication is initiated by expression of the two viral immediate-early transactivators, Zta and Rta. In vitro, reactivation of EBV can be induced by anti-immunoglobulin, tetradecanoyl phorbol acetate, an...

journal_title：Journal of virology

authors： Tsai PF,Lin SJ,Weng PL,Tsai SC,Lin JH,Chou YC,Tsai CH

更新日期：2011-03-01 00:00:00

abstract：UNLABELLED:Cell culture systems reproducing virus replication can serve as unique models for the discovery of novel bioactive molecules. Here, using a hepatitis C virus (HCV) cell culture system, we identified neoechinulin B (NeoB), a fungus-derived compound, as an inhibitor of the liver X receptor (LXR). NeoB was init...

journal_title：Journal of virology

authors： Nakajima S,Watashi K,Ohashi H,Kamisuki S,Izaguirre-Carbonell J,Kwon AT,Suzuki H,Kataoka M,Tsukuda S,Okada M,Moi ML,Takeuchi T,Arita M,Suzuki R,Aizaki H,Kato T,Suzuki T,Hasegawa H,Takasaki T,Sugawara F,Wakita T

更新日期：2016-09-29 00:00:00

abstract：:Adenine residues of 70S avian myeloblastosis virus (AMV) RNA are modified when reacted with chloroacetaldehyde. This modification introduces characteristic fluorescent epsilon-adenosine (epsilonA) probes which were used to monitor the reaction. Under suitable conditions, modified 70S(epsilonA) RNA was maintained intac...

journal_title：Journal of virology

authors： Papas TS,Chirikjian JG,Pry TW,Massicot JG,Irwin RD,Chirigos MA

更新日期：1974-11-01 00:00:00

abstract：:Epstein-Barr virus (EBV) is a ubiquitous human pathogen associated with Burkitt's lymphoma and nasopharyngeal carcinoma. Although the EBV genome harbors more than a hundred genes, a full transcription map with EBV polyadenylation profiles remains unknown. To elucidate the 3' ends of all EBV transcripts genome-wide, we...

journal_title：Journal of virology

authors： Majerciak V,Yang W,Zheng J,Zhu J,Zheng ZM

更新日期：2019-01-04 00:00:00

abstract：UNLABELLED:Pandemic influenza is a major public health concern, but conventional strain-matched vaccines are unavailable early in a pandemic. Candidate "universal" vaccines targeting the viral antigens nucleoprotein (NP) and matrix 2 (M2), which are conserved among all influenza A virus strains and subtypes, could be m...

journal_title：Journal of virology

authors： Price GE,Lo CY,Misplon JA,Epstein SL

更新日期：2014-06-01 00:00:00

abstract：:The membrane fusion events which initiate human immunodeficiency virus type 1 (HIV-1) infection and promote cytopathic syncytium formation in infected cells commence with the binding of the HIV envelope glycoprotein (Env) to CD4 and an appropriate coreceptor. Here, we show that HIV Env-coreceptor interactions activate...

journal_title：Journal of virology

authors： Pontow SE,Heyden NV,Wei S,Ratner L

更新日期：2004-07-01 00:00:00

abstract：:The baculovirus Autographa californica multicapsid nucleopolyhedrovirus (AcMNPV) initiates apoptosis in diverse insects through events triggered by virus DNA (vDNA) replication. To define the proapoptotic pathway and its role in antivirus defense, we investigated the link between the host's DNA damage response (DDR) a...

journal_title：Journal of virology

authors： Mitchell JK,Friesen PD

更新日期：2012-12-01 00:00:00

abstract：:The rotavirus nonstructural phosphoprotein NSP5 is encoded by a gene in RNA segment 11. Immunofluorescence analysis of fixed cells showed that NSP5 polypeptides remained confined to viroplasms even at a late stage when provirions migrated from these structures. When NSP5 was expressed in COS-7 cells in the absence of ...

journal_title：Journal of virology

authors： Blackhall J,Muñoz M,Fuentes A,Magnusson G

更新日期：1998-08-01 00:00:00

abstract：:Apoptosis of virus-infected cells occurs either as a direct response to viral infection or upon recognition of infection by the host immune response. Apoptosis reduces production of new virus from these cells, and therefore viruses have evolved inhibitory mechanisms. We previously showed that laboratory strains of her...

journal_title：Journal of virology

authors： Jerome KR,Fox R,Chen Z,Sears AE,Lee Hy,Corey L

更新日期：1999-11-01 00:00:00

abstract：:The addition of 25 mug of protamine sulfate per ml to lysozyme-ethylenediamine-tetraacetic acid spheroplasts of Escherichia coli stimulates transfection not only for T1 phage deoxyribonucleic acid (DNA; Hotz and Mauser, 1969) but also for the following phage DNA species: lambda, 10,000-fold to an efficiency of 10(-3) ...

journal_title：Journal of virology

authors： Benzinger R,Kleber I,Huskey R

更新日期：1971-05-01 00:00:00