Superinfection exclusion by heteroimmune corynebacteriophages.

abstract：:The Epstein-Barr virus (EBV) BamHI-A rightward transcripts (BARTs) are expressed in all EBV-associated tumors as well as in latently infected B cells in vivo and cultured B-cell lines. One of the BART family transcripts contains an open reading frame, RPMS1, that encodes a nuclear protein termed RPMS. Reverse transcri...

journal_title：Journal of virology

authors： Zhang J,Chen H,Weinmaster G,Hayward SD

更新日期：2001-03-01 00:00:00

abstract：:CtBP has been shown to be a highly conserved corepressor of transcription. E1A and all the various transcription factors to which CtBP binds contain a conserved PLDLS CtBP-interacting domain, and EBNA3C includes a PLDLS motif (amino acids [aa] 728 to 732). Here we show that EBNA3C binds to CtBP both in vitro and in vi...

journal_title：Journal of virology

authors： Touitou R,Hickabottom M,Parker G,Crook T,Allday MJ

更新日期：2001-08-01 00:00:00

abstract：:Rotavirus nonstructural protein 4 (NSP4) induces dramatic changes in cellular calcium homeostasis. These include increased endoplasmic reticulum (ER) permeability, resulting in decreased ER calcium stores and activation of plasma membrane (PM) calcium influx channels, ultimately causing a 2- to 4-fold elevation in cyt...

journal_title：Journal of virology

authors： Hyser JM,Utama B,Crawford SE,Broughman JR,Estes MK

更新日期：2013-12-01 00:00:00

abstract：:A host-mediated RNA-editing event allows hepatitis delta virus (HDV) to express two essential proteins, the small delta antigen (HDAg-S) and the large delta antigen (HDAg-L), from a single open reading frame. One or several members of the ADAR (adenosine deaminases that act on RNA) family are thought to convert the ad...

journal_title：Journal of virology

authors： Sato S,Wong SK,Lazinski DW

更新日期：2001-09-01 00:00:00

abstract：:Encephalomyocarditis virus induced a rapid shutoff of host translation in mouse L cells shortly after infection and before viral proteins were made in detectable amounts. This kinetic pattern is similar to that seen in poliovirus-infected HeLa cells. However, the mechanisms of host shutoff are different in these two c...

journal_title：Journal of virology

authors： Jen G,Thach RE

更新日期：1982-07-01 00:00:00

abstract：:Genotype 1 hepatitis E viruses (HEVs) are restricted to primate hosts, whereas genotype 3 HEVs predominantly infect swine, in addition to primates. In order to identify possible determinants of the host range, infectious recombinant viruses and chimeras of a genotype 1 isolate and a genotype 3 isolate were compared fo...

journal_title：Journal of virology

authors： Nguyen HT,Shukla P,Torian U,Faulk K,Emerson SU

更新日期：2014-01-01 00:00:00

abstract：:The yield of G418-resistant Huh7 cell clones bearing subgenomic dicistronic GB virus B (GBV-B) is significantly affected by the insertion of a portion of the viral core gene between the GBV-B 5' untranslated region and the exogenous neomycin phosphotransferase selector gene (A. De Tomassi, M. Pizzuti, R. Graziani, A. ...

journal_title：Journal of virology

authors： Pizzuti M,De Tomassi A,Traboni C

更新日期：2003-07-01 00:00:00

abstract：:The E6 oncoprotein of high-risk human papillomavirus type 16 (HPV16) interacts with several nuclear transcription factors and coactivators in addition to cytoplasmic proteins, suggesting that nuclear import of HPV16 E6 plays a role in the cellular transformation process. In this study we have investigated the nuclear ...

journal_title：Journal of virology

authors： Le Roux LG,Moroianu J

更新日期：2003-02-01 00:00:00

abstract：:Fine structure marker rescue involving the use of subfragments of vaccinia virus HindIII DNA fragments L, J, and H has been used to map the mutations in eight temperature-sensitive mutants of vaccinia virus representing four complementation groups. Comparison of their map locations with the positions of the open readi...

journal_title：Journal of virology

authors： Ensinger MJ,Weir JP,Moss B

更新日期：1985-12-01 00:00:00

abstract：:Severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) is known to take an endosomal pathway for cell entry; however, it is thought to enter directly from the cell surface when a receptor-bound virion spike (S) protein is affected by trypsin, which induces cleavage of the S protein and activates its fusion po...

journal_title：Journal of virology

authors： Watanabe R,Matsuyama S,Shirato K,Maejima M,Fukushi S,Morikawa S,Taguchi F

更新日期：2008-12-01 00:00:00

abstract：:Hepatitis C virus (HCV) nonstructural protein 5B (NS5B) is an RNA-dependent RNA polymerase (RdRp) that acts as a key player in the HCV replication complex. Understanding the interplay between the viral and cellular components of the HCV replication complex could provide new insight for prevention of the progression of...

journal_title：Journal of virology

authors： Huang JT,Tseng CP,Liao MH,Lu SC,Yeh WZ,Sakamoto N,Chen CM,Cheng JC

更新日期：2013-05-01 00:00:00

abstract：:Budding of retroviruses from cell membranes requires ubiquitination of Gag and recruitment of cellular proteins involved in endosome sorting, including endosome sorting complex required for transport III (ESCRT-III) protein complex and vacuolar protein sorting 4 (VPS4) and its ATPase. In response to infection, a cellu...

journal_title：Journal of virology

authors： Kuang Z,Seo EJ,Leis J

更新日期：2011-07-01 00:00:00

abstract：:In an attempt to identify the molecules involved in the pathogenesis of prion diseases, we performed cDNA subtraction on the brain tissues of mice affected with an experimental prion disease and the unaffected control. The genes identified as being upregulated in the prion-affected brain tissue included those encoding...

journal_title：Journal of virology

authors： Kopacek J,Sakaguchi S,Shigematsu K,Nishida N,Atarashi R,Nakaoke R,Moriuchi R,Niwa M,Katamine S

更新日期：2000-01-01 00:00:00

abstract：:We have used a replication-competent shuttle vector based on the genome of Rous sarcoma virus to characterize genomic rearrangements that occur during retrovirus replication. The strategy involved cloning circular DNA that was generated during an acute infection. While analyzing a class of retroviral DNA clones that a...

journal_title：Journal of virology

authors： Dunn MM,Olsen JC,Swanstrom R

更新日期：1992-10-01 00:00:00

abstract：UNLABELLED:During HIV-1 assembly, the Gag viral proteins are targeted and assemble at the inner leaflet of the cell plasma membrane. This process could modulate the cortical actin cytoskeleton, located underneath the plasma membrane, since actin dynamics are able to promote localized membrane reorganization. In additio...

journal_title：Journal of virology

authors： Thomas A,Mariani-Floderer C,López-Huertas MR,Gros N,Hamard-Péron E,Favard C,Ohlmann T,Alcamí J,Muriaux D

更新日期：2015-08-01 00:00:00

abstract：:Five hepatoma cell lines, including CZHC/8571, PLC/PRF/5, Hep3B, HepG2, and HUH7, were inoculated with three diverse isolates of human immunodeficiency virus type 1 (HIV-1). Productive infection was noted in all hepatoma cell lines, and expression of viral p24 antigen lasted for over 3 months, but its level decreased ...

journal_title：Journal of virology

authors： Cao YZ,Friedman-Kien AE,Huang YX,Li XL,Mirabile M,Moudgil T,Zucker-Franklin D,Ho DD

更新日期：1990-06-01 00:00:00

abstract：:The influenza A virus (IAV) envelope protein hemagglutinin binds α2,6- or α2,3-linked sialic acid as a host cell receptor. Bat IAV subtypes H17N10 and H18N11 form an exception to this rule and do not bind sialic acid but enter cells via major histocompatibility complex (MHC) class II. Here, we review current knowledge...

journal_title：Journal of virology

authors： Karakus U,Pohl MO,Stertz S

更新日期：2020-01-31 00:00:00

abstract：:More than 200 open reading frames (ORFs) from the human cytomegalovirus genome have been reported as potentially coding for proteins. We have used two pattern-based in silico approaches to analyze this set of putative viral genes. With the help of an objective annotation method that is based on the Bio-Dictionary, a c...

journal_title：Journal of virology

authors： Rigoutsos I,Novotny J,Huynh T,Chin-Bow ST,Parida L,Platt D,Coleman D,Shenk T

更新日期：2003-04-01 00:00:00

abstract：:High concentrations of either trypsin or chymotrypsin caused nearly complete cleavage of capsid protein VP2 of hepatitis A virus but did not significantly reduce the infectivity, thermostability, or antigenicity of the virus. Chymotrypsin also had a lesser effect on VP1. These findings indicate the presence of a prote...

journal_title：Journal of virology

authors： Lemon SM,Amphlett E,Sangar D

更新日期：1991-10-01 00:00:00

abstract：:Long-acting antiretrovirals could provide a useful alternative to daily oral therapy for HIV-1-infected individuals. Building on a bi-specific molecule with adnectins targeting CD4 and gp41, a potential long-acting biologic, GSK3732394, was developed with three independent and synergistic modes of HIV entry inhibition...

journal_title：Journal of virology

authors： Wensel D,Sun Y,Davis J,Li Z,Zhang S,McDonagh T,Langley D,Mitchell T,Tabruyn S,Nef P,Cockett M,Krystal M

更新日期：2019-09-30 00:00:00

abstract：:We have developed idiotype-anti-idiotype monoclonal antibodies that provide evidence for rabies virus binding to the acetylcholine receptor (AChR). Hybridoma cell lines 7.12 and 7.25 resulted after fusion of NS-1 myeloma cells with spleen cells from a BALB/c mouse immunized with rabies virus strain CVS. Antibody 7.12 ...

journal_title：Journal of virology

authors： Hanham CA,Zhao F,Tignor GH

更新日期：1993-01-01 00:00:00

abstract：:Phosphorylation of the expressed NS5A protein of hepatitis C virus (HCV), a member of the Hepacivirus genus of the family Flaviviridae, has been demonstrated in mammalian cells and in a cell-free assay by an associated kinase activity. In this report, phosphorylation is also shown for the NS5A and NS5 proteins, respec...

journal_title：Journal of virology

authors： Reed KE,Gorbalenya AE,Rice CM

更新日期：1998-07-01 00:00:00

abstract：:Respiratory syncytial (RS) virus infects the epithelium of the respiratory tract. We examined the replication and maturation of RS virus in two polarized epithelial cell lines, Vero C1008 and MDCK. Electron microscopy of RS virus-infected Vero C1008 cells revealed the presence of pleomorphic viral particles budding ex...

journal_title：Journal of virology

authors： Roberts SR,Compans RW,Wertz GW

更新日期：1995-04-01 00:00:00

abstract：:Human herpesvirus 7 (HHV-7) is a recently isolated betaherpesvirus that is prevalent in the human population, with primary infection usually occurring in early childhood. HHV-7 is related to human herpesvirus 6 (HHV-6) in terms of both biological and, from limited prior DNA sequence analysis, genetic criteria. However...

journal_title：Journal of virology

authors： Nicholas J

更新日期：1996-09-01 00:00:00

abstract：:Cell extracts from murine A9 or human HeLa cells containing wild-type copies the NS1 polypeptide of minute virus of mice (MVM), produced from a recombinant vaccinia virus, can support the resolution of viral 3' termini from palindromic junction fragments of dimeric, replicative-form MVM DNA. Resolution resulted in the...

journal_title：Journal of virology

authors： Cotmore SF,Nüesch JP,Tattersall P

更新日期：1993-03-01 00:00:00

abstract：:Herpes simplex virus 1 (HSV-1) causes significant morbidity and mortality in humans worldwide. HSV-1 enters epithelial cells via an endocytosis mechanism that is low-pH dependent. However, the precise intracellular pathway has not been identified, including the compartment where fusion occurs. In this study, we utiliz...

journal_title：Journal of virology

authors： Tebaldi G,Pritchard SM,Nicola AV

更新日期：2020-11-23 00:00:00

abstract：:Prion diseases are progressive fatal neurodegenerative illnesses caused by the accumulation of transmissible abnormal prion protein (PrP). To find treatments for prion diseases, we searched for substances from natural resources that inhibit abnormal PrP formation in prion-infected cells. We found that high-molecular-w...

journal_title：Journal of virology

authors： Hamanaka T,Nishizawa K,Sakasegawa Y,Oguma A,Teruya K,Kurahashi H,Hara H,Sakaguchi S,Doh-Ura K

更新日期：2017-02-28 00:00:00

abstract：:Hepatitis delta antigen (HDAg) is the only known protein of hepatitis delta virus and was previously shown to localize in the nucleoplasm of infected liver cells. In this study, nuclear localization signals of HDAg were defined by expressing various domains of the antigen in both hepatic and nonhepatic cells as beta-g...

journal_title：Journal of virology

authors： Chang MF,Chang SC,Chang CI,Wu K,Kang HY

更新日期：1992-10-01 00:00:00

abstract：:The replication of positive-strand RNA viral genomes involves various cis-acting RNA sequences. Generally, regulatory RNA sequences are present at or near genomic termini; however, internal replication elements (IREs) also exist. Here we report the structural and functional characterization of an IRE present in the re...

journal_title：Journal of virology

authors： Monkewich S,Lin HX,Fabian MR,Xu W,Na H,Ray D,Chernysheva OA,Nagy PD,White KA

更新日期：2005-04-01 00:00:00

abstract：:Lysine-specific demethylase 1 (LSD1) targets cellular proteins, including histone H3, p53, E2F, and Dnmt1, and is involved in the regulation of gene expression, DNA replication, the cell cycle, and the DNA damage response. LSD1 catalyzes demethylation of histone H3K9 associated with herpes simplex virus 1 (HSV-1) imme...

journal_title：Journal of virology

authors： Harancher MR,Packard JE,Cowan SP,DeLuca NA,Dembowski JA

更新日期：2020-09-15 00:00:00