Intracellular and extracellular calcium ions in transmitter release at the neuromuscular synapse.

abstract：:Nanomedicine is the application of nanotechnology to the discipline of medicine: the use of nanoscale materials for the diagnosis, monitoring, control, prevention, and treatment of disease. Nanomedicine holds tremendous promise to revolutionize medicine across disciplines and specialties, but this promise has yet to b...

journal_title：Annals of the New York Academy of Sciences

authors： Tinkle S,McNeil SE,Mühlebach S,Bawa R,Borchard G,Barenholz YC,Tamarkin L,Desai N

更新日期：2014-04-01 00:00:00

abstract：:This study measured on-road driving behavior in subjects with bilateral vestibular loss (BVL). Data included point-of-regard (what the driver is looking at and attending to), gaze stability (the performance of the vestibulo-ocular reflex), and head movement, during complex maneuvers such as changing lanes, cornering, ...

journal_title：Annals of the New York Academy of Sciences

authors： MacDougall HG,Moore ST,Black RA,Jolly N,Curthoys IS

更新日期：2009-05-01 00:00:00

abstract：:Spinal cord injury remains with limited natural recovery and only a few general ineffective treatment options. Recent publications have reported enhanced neurologic recovery with the use of methylprednisolone and GM-1 ganglioside. The results of the Maryland GM-1 Ganglioside Study reported a significant drug effect wi...

journal_title：Annals of the New York Academy of Sciences

authors： Geisler FH

更新日期：1998-06-19 00:00:00

abstract：:The alpha-ketoglutarate dehydrogenase complex (KGDHC) is an important mitochondrial constituent, and deficiency of KGDHC is associated with a number of neurological disorders. KGDHC is composed of three proteins, each encoded on a different and well-characterized gene. The sequences of the human proteins are known. Th...

journal_title：Annals of the New York Academy of Sciences

authors： Sheu KF,Blass JP

更新日期：1999-01-01 00:00:00

abstract：:Violence against women has been a problem in human cultures for centuries. This is still the case both in developed and in developing countries, but it is in developing countries where the problem is aggravated as the result of cultural norms that are tolerant of men exerting power over women and girls as a commonly a...

journal_title：Annals of the New York Academy of Sciences

authors： Pick S,Contreras C,Barker-Aguilar A

更新日期：2006-11-01 00:00:00

abstract：:Cardiac development is characterized by a complex interplay of chemical, mechanical, and electrical forces, which together contribute to the proper formation of the heart muscle. In adult myocardium, cardiomyocytes are elongated, well-coupled by gap junctions, and organized in spatially well-defined muscle fibers. Thi...

journal_title：Annals of the New York Academy of Sciences

authors： Pijnappels DA,Gregoire S,Wu SM

更新日期：2010-02-01 00:00:00

abstract：:Primates have stimulated more interest than any other group as humans are ranked in this same mammalian order. Gustatory responses of human and nonhuman primates have already been compared for compounds such as monosaccharides, oligosaccharides, polyols, amino acids, dipeptides, proteins, dihydrochalcones, sulfamates,...

journal_title：Annals of the New York Academy of Sciences

authors： Glaser D,Tinti JM,Nofre C

更新日期：1998-11-30 00:00:00

abstract：:Thymosin proteins, originally isolated from fractionation of thymus tissue, represent a class of compounds that we now know are present in numerous other tissues, are unrelated to each other in a genetic sense, and appear to have different functions within the cell. Thymosin α1 (generic drug name thymalfasin; trade na...

journal_title：Annals of the New York Academy of Sciences

authors： Volk DE,Tuthill CW,Elizondo-Riojas MA,Gorenstein DG

更新日期：2012-10-01 00:00:00

abstract：:Ischemic stroke is one of the leading causes of death and morbidity worldwide, and systemic thrombolytic treatment is still the first-line therapy within 4.5 h from symptom onset. Selecting patients for treatment response is mandatory in any time window but challenging as well. The authors aim to support stroke physic...

journal_title：Annals of the New York Academy of Sciences

authors： Hametner C,Ringleb PA,Hacke W,Kellert L

更新日期：2012-09-01 00:00:00

abstract：:The Buddhist view of the origin of the universe is discussed. One of the basic tenets of Buddhism is the concept of interdependence which says that all things exist only in relationship to others, and that nothing can have an independent and autonomous existence. The world is a vast flow of events that are linked toge...

journal_title：Annals of the New York Academy of Sciences

authors： Thuan TX

更新日期：2001-12-01 00:00:00

abstract：:This study aimed to assess the value of different DXA and BIA models for predicting muscle volume in mid-thigh segments obtained by MRI. Three DXA models were used: in model A, muscle was taken to be equivalent to fat-free soft tissue; in model B the thigh segment was divided into its constituent tissues using fixed a...

journal_title：Annals of the New York Academy of Sciences

authors： Elia M,Fuller NJ,Hardingham CR,Graves M,Screaton N,Dixon AK,Ward LC

更新日期：2000-05-01 00:00:00

abstract：:In this paper, we develop an agent-based model of social influence on body weight. The model's assumptions are grounded in theory and evidence from physiology, social psychology, and behavioral science, and its outcomes are tested against longitudinal data from American youth. We discuss the implementation of the mode...

journal_title：Annals of the New York Academy of Sciences

authors： Hammond RA,Ornstein JT

更新日期：2014-12-01 00:00:00

abstract：:Hormones and neuropeptides may influence the activities of lymphoid organs and cells via endocrine and local autocrine/paracrine pathways. A paradigm of the interactions between the neuroendocrine and immune system is sophisticatedly represented in the thymus. Indeed, receptors for these molecules are heterogeneously ...

journal_title：Annals of the New York Academy of Sciences

authors： Ferone D,Boschetti M,Resmini E,Giusti M,Albanese V,Goglia U,Albertelli M,Vera L,Bianchi F,Minuto F

更新日期：2006-06-01 00:00:00

abstract：:Smaller, more charge-intensive electrodes are needed for "safe" stimulation of the nervous system. In this paper we review critical concepts and the state of the art in electrodes. Control of charge density and charge balance are essential to avoid tissue electrolysis. Chemical criteria for "safe" stimulation are revi...

journal_title：Annals of the New York Academy of Sciences

authors： Brummer SB,Robblee LS,Hambrecht FT

更新日期：1983-01-01 00:00:00

abstract：:Predicting the response to xenotransplantation is difficult, but can be based upon (i) past clinical experience, (ii) opinion surveys and focus groups, (iii) predictable variables, and (iv) the allotransplant experience. Baby Fae, the Pittsburgh baboon liver transplants, and the Jeff Getty baboon marrow transplant hav...

journal_title：Annals of the New York Academy of Sciences

authors： Daar AS

更新日期：1998-12-30 00:00:00

abstract：:The muscular dystrophies, which cause progressive weakening of the skeletal muscles, are frequently associated with cardiomyopathy. In fact, the leading cause of mortality in patients with Duchenne muscular dystrophy, the most common and most severe type of muscular dystrophy, is heart failure due to cardiomyopathy. T...

journal_title：Annals of the New York Academy of Sciences

authors： Kuno A,Tanno M,Horio Y

更新日期：2015-08-01 00:00:00

abstract：:The free radical theory of aging proposes that oxidative stress is one of the determinants of an organism's life span. In Caenorhabditis elegans, genetic or environmental changes have been shown to modulate life span. Here we discuss whether changes in the generation and destruction of free radicals are implicated in ...

journal_title：Annals of the New York Academy of Sciences

authors： Honda Y,Honda S

更新日期：2002-04-01 00:00:00

abstract：:Twenty female imago of Haemaphysalis concinnae ticks collected from wild vegetation in May of 2001 in the Obor region near Khabarovsk in the Russian Far East were studied. DNA was extracted with commercially available kits following manufacturer's instructions. We used broad range primers SFG3 and SFG6 proposed for am...

journal_title：Annals of the New York Academy of Sciences

authors： Mediannikov O,Ivanov L,Nishikawa M,Saito R,Sidelnikov YN,Zdanovskaya NI,Tarasevich IV,Suzuki H

更新日期：2003-06-01 00:00:00

abstract：:Epidemiological observations, clinical mechanistic studies, and basic laboratory research suggest that estrogen therapy is associated with beneficial cardiovascular effects in postmenopausal women. Estrogen has a multitude of biological effects that may account for this apparent benefit (which remains to be proved in ...

journal_title：Annals of the New York Academy of Sciences

authors： Blum A,Cannon RO 3rd

更新日期：2001-12-01 00:00:00

abstract：:The striatum is the major input nucleus of the basal ganglia. It is thought to play a key role in learning on the basis of positive reinforcement and in action selection. One view of the striatum conceives it as comprising a reiterated matrix of processing units that perform common operations in different striatal reg...

journal_title：Annals of the New York Academy of Sciences

authors： Wickens JR,Budd CS,Hyland BI,Arbuthnott GW

更新日期：2007-05-01 00:00:00

abstract：:Management of gastroesophageal junction (GEJ) adenocarcinoma is a controversial topic. The rising incidence of this cancer requires a clear consensus to ensure proper management. Application of oncological principles for tumors of the esophagus or stomach is not possible because of comparative differences in the biolo...

journal_title：Annals of the New York Academy of Sciences

authors： Chevallay M,Bollschweiler E,Chandramohan SM,Schmidt T,Koch O,Demanzoni G,Mönig S,Allum W

更新日期：2018-12-01 00:00:00

abstract：:The four diseases discussed in this chapter (dracunculiasis, onchocerciasis, schistosomiasis, and trachoma) are among the officially designated "Neglected Tropical Diseases," and each is also both the result of and a contributor to the poverty of many rural populations. To various degrees, they all have adverse effect...

journal_title：Annals of the New York Academy of Sciences

authors： Hopkins DR,Richards FO Jr,Ruiz-Tiben E,Emerson P,Withers PC Jr

更新日期：2008-01-01 00:00:00

abstract：:1. One can accurately predict the contribution of each inhibitor to the total inactivation of an enzyme in plasma once its pseudo-first-order reaction rate constant and concentration are known. 2. Because the mechanism of augmentation of the inactivation rate of an enzyme by ATIII occurs via formation of an ATIII-hepa...

journal_title：Annals of the New York Academy of Sciences

authors： Colman RW,Scott CF,Pixley RA,de la Cadena RA

更新日期：1989-01-01 00:00:00

abstract：:During the past decade, a considerable body of evidence has emerged showing that circumstances during the fetal period may have lifelong programming effects on different body functions with a considerable impact on disease susceptibility. The purpose of this article is to provide a synopsis of these findings and their...

journal_title：Annals of the New York Academy of Sciences

authors： Kajantie E

更新日期：2006-11-01 00:00:00

abstract：:The osteoclast (OCL) is derived from the cells in monocyte-macrophage lineage. The earliest identifiable OCL precursor is the granulocyte-macrophage colony-forming unit (CFU-GM), which gives rise to granulocytes, monocytes, and OCL. CFU-GM-derived cells then differentiate to committed OCL precursors, which are post-mi...

journal_title：Annals of the New York Academy of Sciences

authors： Roodman GD

更新日期：2006-04-01 00:00:00

abstract：:Vestibular stimulation by head accelerations always involves multisensory activation of the vestibular, somatosensory, and visual systems. Over the past few years, galvanic vestibular stimulation (GVS) has become increasingly popular for testing vestibular function for clinical and research purposes. Although GVS prov...

journal_title：Annals of the New York Academy of Sciences

authors： Jahn K,Naessl A,Strupp M,Schneider E,Brandt T,Dieterich M

更新日期：2003-10-01 00:00:00

abstract：:These experiments sought to: (1) determine if alpha 2/I1 agonists that are topically active on the eye have similar effects on intraocular pressure when applied to the CNS and (2) ascertain whether these agents lower IOP, in part, via central alpha 2 receptors and/or imidazoline (I1) receptors. New Zealand White rabbi...

journal_title：Annals of the New York Academy of Sciences

authors： Campbell WR,Potter DE

更新日期：1995-07-12 00:00:00

abstract：:The aim of this study was to examine changes in muscle cell injury and antioxidant capacity of weightlifters following a 1-week intensive resistance-training regimen. Thirty-six female subjects participated in this study, and their ages ranged from 18 to 25 years. The sample group included 19 elite weightlifters with ...

journal_title：Annals of the New York Academy of Sciences

authors： Liu JF,Chang WY,Chan KH,Tsai WY,Lin CL,Hsu MC

更新日期：2005-05-01 00:00:00

abstract：:In the present study we analyzed the morphology of testes and efferent ducts as well as the localization of androgen receptors (AR) in the tissues of XY, YY, and XX male rainbow trout Oncorhynchus mykiss Walbaum. Testes of the XX trout differed distinctly from those of XY and YY males; the interstitial space was very ...

journal_title：Annals of the New York Academy of Sciences

authors： Galas JF,Hejmej A,Glogowski J,Bilińska B

更新日期：2009-04-01 00:00:00

abstract：:The availability of new food composition carotenoid values for fruits and vegetables increases our ability to test hypotheses concerning the role of antioxidant nutrients and cancer risk. To estimate the usual carotenoid intakes, a quantitative diet history covering a one-year period is recommended for epidemiologic s...

journal_title：Annals of the New York Academy of Sciences

authors： Hankin JH,Le Marchand L,Kolonel LN,Wilkens LR

更新日期：1993-12-31 00:00:00