Torsional eye movement responses to monaural and binaural galvanic vestibular stimulation: side-to-side asymmetries.

abstract：:In adult Lurcher mice virtually all cerebellar Purkinje cells have degenerated as a direct consequence of mutant gene action, providing a natural model for studying the effect of cerebellar cortical lesions on the generation of compensatory eye movements. Lurcher mice possess both optokinetic (OKR) and vestibular (VOR...

journal_title：Annals of the New York Academy of Sciences

authors： Van Alphen AM,Schepers T,Luo C,De Zeeuw CI

更新日期：2002-12-01 00:00:00

abstract：:A hallmark of success for early career biomedical researchers is the acquisition of research funding. There are marked disparities among principal investigators who submit grants and the likelihood of receiving national funding. The National Research Mentoring Network was funded by the National Institutes of Health to...

journal_title：Annals of the New York Academy of Sciences

authors： Harwood EM,Jones AR,Erickson D,Buchwald D,Johnson-Hemming J,Jones HP,Manson S,McGee R,Smith A,Steer CJ,Vishwanatha JK,Weber-Main AM,Okuyemi KS

更新日期：2019-06-01 00:00:00

abstract：:The present experiments were conducted to determine the effects of neurotensin on secretion of a variety of anterior pituitary hormones. Conscious rats with indwelling cannulae in the third ventricle and external jugular vein were used and the effects on plasma hormone levels measured by radioimmunoassay. Neurotensin ...

journal_title：Annals of the New York Academy of Sciences

authors： McCann SM,Vijayan E,Koenig J,Krulich L

更新日期：1982-01-01 00:00:00

abstract：:In the study reported in this paper, we characterized PACAP in the human fetal adrenal gland and we investigated the effect of PACAP on steroid secretion from cultured fetal adrenal cells. The adrenal gland from 20-week-old fetuses contained substantial concentrations of PACAP-immunoreactive material (88.6 ng/g wet ti...

journal_title：Annals of the New York Academy of Sciences

authors： Breault L,Yon L,Montéro M,Chouinard L,Contesse V,Delarue C,Fournier A,Lehoux JG,Vaudry H,Gallo-Payet N

更新日期：2000-01-01 00:00:00

abstract：:A human T-T hybridoma was produced, which was a fusion product between and HGPRT-deficient T-cell line, Jurkat 3, and an OKT4+ activated peripheral blood T-cell. The hybrid expressed a receptor for IgM Fc and was negative for IgA Fc. It was shown to produce a factor capable of specifically enhancing IgA production and...

journal_title：Annals of the New York Academy of Sciences

authors： Mayer L,Fu SM,Kunkel HG

更新日期：1983-06-30 00:00:00

abstract：:Investigations of the I-Ek-restricted, cytochrome c-specific T-cell response in mice show that both T-cell receptor V alpha and V beta CDR3 residues and the use of particular V alpha s and V beta s are necessary for recognition. Data strongly suggest that specific CDR3 residues are important in contacting the peptide....

journal_title：Annals of the New York Academy of Sciences

authors： Davis MM,McHeyzer-Williams M,Chien YH

更新日期：1995-07-07 00:00:00

abstract：:Colorectal cancer is the third most frequent fatal malignant neoplasm in the United States and is expected to cause significant morbidity and mortality. The recent recall of cyclooxygenase-2 inhibitors from clinical trials highlights the need to develop other agents for cancer chemoprevention trials. Intervention stra...

journal_title：Annals of the New York Academy of Sciences

authors： Nelson MA,Goulet AC,Jacobs ET,Lance P

更新日期：2005-11-01 00:00:00

abstract：:Dysregulation of apoptosis is associated with the pathogenesis of organ-specific autoimmune diseases, through altered target organ susceptibility. Apoptosis signaling pathways can be initiated through activation of death receptors such as Fas. A comparative analysis of the expression of Fas and FasL, the antiapoptotic...

journal_title：Annals of the New York Academy of Sciences

authors： Salmaso C,Bagnasco M,Pesce G,Montagna P,Brizzolara R,Altrinetti V,Richiusa P,Galluzzo A,Giordano C

更新日期：2002-06-01 00:00:00

abstract：:The availability of immunodeficient mice engrafted with functional human immune systems and islets permits in vivo study of human diabetes without putting patients at risk. ...

journal_title：Annals of the New York Academy of Sciences

authors： Greiner DL,Brehm MA,Hosur V,Harlan DM,Powers AC,Shultz LD

更新日期：2011-12-01 00:00:00

abstract：:In 2014, there was an outbreak of beriberi on Kuria, a remote atoll in Kiribati, a small Pacific Island nation. A thiamine-poor diet consisting mainly of rice, sugar, and small amounts of fortified flour was likely to blame. We aimed to design a food fortification strategy to improve thiamine intakes in Kuria. We surv...

journal_title：Annals of the New York Academy of Sciences

authors： Green TJ,Whitfield KC,Daniels L,Brown RC,Houghton LA

更新日期：2021-01-12 00:00:00

abstract：:Most of the plasma suppressive activity was associated with alpha 2M in both normal subjects and cancer patients. alpha 2M binding to physiological levels of proteases was associated with an increase in the ability to suppress lymphocyte reactivity in the TEEM test. alpha 2M binding to proteases released a peptide tha...

journal_title：Annals of the New York Academy of Sciences

authors： Alomran A,Shenton BK,Donnelly PK,Francis DM,Proud G,Taylor RM

更新日期：1983-01-01 00:00:00

abstract：:These initial studies show that deregulated expression of ALG7 affects diverse cellular functions crucial to development, including proliferation, differentiation, and morphogenesis. Furthermore, the data suggest multiple genetic targets for ALG7 and provide the basis for future dissection of these developmentally rel...

journal_title：Annals of the New York Academy of Sciences

authors： Lennon K,Bird A,Kukuruzinska MA

更新日期：1998-04-15 00:00:00

abstract：:This review outlines the scientific rationale supporting the potential use of deep-brain electrical stimulation (DBS) in the central thalamus as a method to improve behavioral responsiveness following severe brain injury. Neurons within the central thalamus are selectively vulnerable to disconnection and dysfunction f...

journal_title：Annals of the New York Academy of Sciences

authors： Schiff ND

更新日期：2009-03-01 00:00:00

abstract：:Phosphomannose isomerase (PMI), an enzyme not present in many plants, catalyzes the reversible interconversion of mannose 6-phosphate and fructose 6-phosphate. Plant cells lacking this enzyme are incapable of surviving on synthetic medium containing mannose. Thus PMI/mannose selection has utility in the identification...

journal_title：Annals of the New York Academy of Sciences

authors： Privalle LS

更新日期：2002-05-01 00:00:00

abstract：:Studies in humans and in animal models have demonstrated that the receptor-dependent actions of 1,25-dihydroxyvitamin D are required for normal skeletal growth and maturation. Investigations were undertaken to address which consequences of vitamin D receptor deficiency are a direct result of impaired receptor-dependen...

journal_title：Annals of the New York Academy of Sciences

authors： Demay MB

更新日期：2006-04-01 00:00:00

abstract：:One of the most studied effects of verbal working memory (WM) is the influence of the length of the words that compose the list to be remembered. This work aims to investigate the nature of musical WM by replicating the word length effect in the musical domain. Length and rate of presentation were manipulated in a rec...

journal_title：Annals of the New York Academy of Sciences

authors： Akiva-Kabiri L,Vecchi T,Granot R,Basso D,Schön D

更新日期：2009-07-01 00:00:00

abstract：:Thymosin proteins, originally isolated from fractionation of thymus tissue, represent a class of compounds that we now know are present in numerous other tissues, are unrelated to each other in a genetic sense, and appear to have different functions within the cell. Thymosin α1 (generic drug name thymalfasin; trade na...

journal_title：Annals of the New York Academy of Sciences

authors： Volk DE,Tuthill CW,Elizondo-Riojas MA,Gorenstein DG

更新日期：2012-10-01 00:00:00

abstract：:Women are four to eight times more likely to be affected by fibromyalgia syndrome (FMS). A lack of cortisol, potentially due to an adrenocortical deficit is postulated in FMS. The cause of such adrenal insufficiency is unknown. It could be assumed that stress exposure during critical periods contributes to vulnerabili...

journal_title：Annals of the New York Academy of Sciences

authors： Klingmann PO,Kugler I,Steffke TS,Bellingrath S,Kudielka BM,Hellhammer DH

更新日期：2008-12-01 00:00:00

abstract：:We examined the role of I1-imidazoline (I1-IR) receptors in control of airway function, by testing the effects of systemic administration of the I1-IR agonist moxonidine on reflex responses of tracheal smooth muscle (TSM) tone to either lung deflation or mechanical stimulation of intrapulmonary rapidly adapting recept...

journal_title：Annals of the New York Academy of Sciences

authors： Haxhiu MA,Dreshaj IA,McFadden CB,Erokwu BO,Ernsberger P

更新日期：1999-06-21 00:00:00

abstract：:From the time Dan was 12 years old to the present, he always was the explorer of life. He was very fortunate in having an opportunity to see how life exists in several human societies around the world. His many professional foreign travels are presented. Dan went to a 1959 meeting in Argentina, to England in 1963, and...

journal_title：Annals of the New York Academy of Sciences

authors： Gilbert C,Gilbert RL

更新日期：2000-01-01 00:00:00

abstract：:The W-curve is a numerical mapping algorithm that provides tertiary information content of long and short genomic sequences. The most popular genomic pattern recognition algorithms depend on string matching of the primary information content of short genomic sequences. Herein, we describe a way to define the fuzzy pro...

journal_title：Annals of the New York Academy of Sciences

authors： Cork DJ,Toguem A

更新日期：2002-12-01 00:00:00

abstract：:Helicobacter pylori is a definite carcinogen whose mechanism of action is still unknown. The aim of this work was (1) to determine the presence of p53 protein and related antibodies in patients affected by various gastric pathologies and chronically infected with H. pylori, and (2) to try to discover a test to be used...

journal_title：Annals of the New York Academy of Sciences

authors： Losi E,Molinari AM,Gazzerro P,Ortega De Luna L,Fera MT,Carbone M,Catania MR,Hasty DL,Rossano F

更新日期：2002-06-01 00:00:00

abstract：:An apparently macromolecular factor is isolated from aqueous skin extracts which inhibits DNA synthesis in vivo and in vitro with high efficacy (ID50 in vivo 0.2 pmol/g, in vitro 0.2 pM) and in a highly specific manner showing a point of attack in the late G1-phase of the cell cycle (epidermal G1-chalone). Preliminary...

journal_title：Annals of the New York Academy of Sciences

authors： Richter KH,Clauss M,Höfle W,Schnapke R,Marks F

更新日期：1988-01-01 00:00:00

abstract：:In natural tissues, cells form multiple attachment sites to their extracellular matrix. By means of those attachments, cells deform as the tissue deforms in response to the natural mechanical stresses and strains that the tissue must sustain during function. These mechanical forces are the energy input that instruct t...

journal_title：Annals of the New York Academy of Sciences

authors： Urry DW,Pattanaik A

更新日期：1997-12-31 00:00:00

abstract：:In red blood cells as well as in platelets there appears to be a decrease in adenine nucleotides during storage under blood bank conditions. This can be decreased by use of anticoagulant preservatives with higher phosphate content than the standard ACD solution, through the addition of adenine and inosine. Maintenance...

journal_title：Annals of the New York Academy of Sciences

authors： Ambrus JL,Ambrus CM,Odake K,Mink IB,Shields R,Warner W,Bishop C,Tritsch GL,Golden G,Mittelman A

更新日期：1975-08-08 00:00:00

abstract：:We have created genetically altered mice to investigate how expression of the Na(+)-Ca(2+) exchange protein alters excitation-contraction (E-C) coupling. Whereas low levels of exchanger overexpression have minimal effects on E-C coupling properties, high levels of overexpression in homozygous animals results in suscep...

journal_title：Annals of the New York Academy of Sciences

authors： Goldhaber JI,Henderson SA,Reuter H,Pott C,Philipson KD

更新日期：2005-06-01 00:00:00

abstract：:Propagation of a kerosene spray formed by a prefilming airblast atomizer within a pulsating flame has been investigated. The measurements were performed in a 400 kW single combustor rig at typical engine conditions of up to 0.8 MPa inlet pressure and 673 K inlet temperature. The homogeneity of the fuel spray propagati...

journal_title：Annals of the New York Academy of Sciences

authors： Schober P,Meier R,Schäfer O,Wittig S

更新日期：2002-10-01 00:00:00

abstract：:These studies demonstrate that photochemotherapy can be successfully evaluated in animal models. The therapy mediates specific suppression of immune responses and appears to operate at the level of the effector T cells. Future studies will focus on isolation and characterization of the host response to photochemothera...

journal_title：Annals of the New York Academy of Sciences

authors： Berger CL,Edelson RL,Edwards N,Sanchez J,Coppey L,He X,Marboe C,Rose E

更新日期：1991-12-30 00:00:00

abstract：:Extension of mammalian health and life span has been achieved using various dietary interventions. We previously reported that restricting dietary methionine (MET) content extends life span only when growth hormone signaling is intact (no life span increase in GH deficiency or GH resistance). To understand the metabol...

journal_title：Annals of the New York Academy of Sciences

authors： Brown-Borg HM,Rakoczy S,Wonderlich JA,Borg KE,Rojanathammanee L

更新日期：2018-04-01 00:00:00

abstract：:Gene regulation mechanisms have evolved allowing cells to finetune the level of "endogenous" oxidative stress and to cope with increased free radicals from external sources. Levels of H2O2 are tightly controlled in E. coli by OxyR, which is activated by H2O2 to increase scavenging activities and limit H2O2 generation ...

journal_title：Annals of the New York Academy of Sciences

authors： González-Flecha B,Demple B

更新日期：2000-01-01 00:00:00