Essential oils and functional herbs for healthy aging.

abstract：:In the present study, we used immunohistochemistry and western blot analysis to examine changes in the levels and cellular localization of iron, heavy chain ferritin (ferritin-H), and transferrin in the gerbil hippocampal CA1 region from 30 minutes to 7 days following transient forebrain ischemia. Relative to sham con...

journal_title：Neural regeneration research

authors： Yoo DY,Yoo KY,Park JH,Kwon HJ,Jung HY,Kim JW,Choi GM,Moon SM,Kim DW,Yoon YS,Won MH,Hwang IK

更新日期：2016-06-01 00:00:00

abstract：:Huntington's disease (HD) is an autosomal-dominant neurodegenerative disease characterized by the selective loss of neurons in the striatum and cortex, leading to progressive motor dysfunction, cognitive decline and behavioral symptoms. HD is caused by a trinucleotide (CAG) repeat expansion in the gene encoding for hu...

journal_title：Neural regeneration research

authors： Colpo GD,Stimming EF,Rocha NP,Teixeira AL

更新日期：2017-09-01 00:00:00

abstract：:Baicalin, a type of flavonoid extracted from the dried root of Scutellaria baicalensis georgi, has been shown to effectively inhibit cell apoptosis. Therefore, we assumed that baicalin would suppress co-listin sulfate-induced neuronal apoptosis. PC12 cells exposed to colistin sulfate (62.5-500 μg/mL) for 24 hours resu...

journal_title：Neural regeneration research

authors： Jiang H,Lv P,Li J,Wang H,Zhou T,Liu Y,Lin W

更新日期：2013-10-05 00:00:00

abstract：:Temporal lobe epilepsy is associated with astrogliosis. Notch1 signaling can induce astrogliosis in glioma. However, it remains unknown whether Notch1 signaling is involved in the pathogenesis of epilepsy. This study investigated the presence of Notch1, hairy and enhancer of split-1, and glial fibrillary acidic protei...

journal_title：Neural regeneration research

authors： Liu X,Yang Z,Yin Y,Deng X

更新日期：2014-03-01 00:00:00

abstract：:Various studies have reported that galanin can promote axonal regeneration of dorsal root ganglion neurons in vitro and inhibit neuropathic pain. However, little is known about its effects on diabetic peripheral neuropathy, and in vivo experimental data are lacking. We hypothesized that repeated applications of exogen...

journal_title：Neural regeneration research

authors： Xu XF,Zhang DD,Liao JC,Xiao L,Wang Q,Qiu W

更新日期：2016-09-01 00:00:00

abstract：:Lentivirus carrying the Atoh1 gene can infect Corti's organ and express a hair-like cell surface marker in the supporting cell area. However, expression of the gene carried by adenovirus is instantaneous, which undoubtedly limits its clinical application. Lentivirus acts as a carrier that can stably and continuously e...

journal_title：Neural regeneration research

authors： Pan S,Wan J,Liu S,Zhang S,Xiong H,Zhou J,Xiong W,Yu K,Fu Y

更新日期：2013-06-15 00:00:00

abstract：:Sterile inflammatory processes are essential for the maintenance of central nervous system homeostasis, but they also contribute to various neurological disorders, including neurotrauma, stroke, and demyelinating or neurodegenerative diseases. Immune mechanisms in the central nervous system and periphery are regulated...

journal_title：Neural regeneration research

authors： Klegeris A

更新日期：2021-03-01 00:00:00

abstract：:Epidural electrical stimulation can restore limb motor function after spinal cord injury by reactivating the surviving neural circuits. In previous epidural electrical stimulation studies, single electrode sites and continuous tetanic stimulation have often been used. With this stimulation, the body is prone to declin...

journal_title：Neural regeneration research

authors： Wang S,Zhang LC,Fu HT,Deng JH,Xu GX,Li T,Ji XR,Tang PF

更新日期：2021-03-01 00:00:00

abstract：:The present study analyzed changes in Wnt3a expression during differentiation of adipose-derived stem cells into cholinergic neurons. Immunocytochemistry and immunofluorescence revealed significantly increased nestin, neuron-specific enolase, microtubule-associated protein 2, and choline acetyltransferase expression i...

journal_title：Neural regeneration research

authors： Liu B,Deng C,Zhang Y,Zhang J

更新日期：2012-07-05 00:00:00

abstract：:An accurate and effective neurological evaluation is indispensable in the treatment and rehabilitation of traumatic brain injury. However, most of the existing evaluation methods in basic research and clinical practice are not objective or intuitive for assessing the neurological function of big animals, and are also ...

journal_title：Neural regeneration research

authors： Jiang JP,Niu XG,Dai C,Ma K,Xu HY,Cheng SX,Zhang ZW,Duan F,Zhu X,Wang YT,Chen XY,Zhang S

更新日期：2019-06-01 00:00:00

abstract：:Molecular mechanisms of the Krüppel-like family of transcription factors (KLFs) have been studied more in proliferating cells than in post-mitotic cells such as neurons. We recently found that KLFs regulate intrinsic axon growth ability in central nervous system (CNS) neurons including retinal ganglion cells, and hipp...

journal_title：Neural regeneration research

authors： Apara A,Goldberg JL

更新日期：2014-08-01 00:00:00

abstract：:Gelatinases matrix metalloproteinase-2 and matrix metalloproteinase-9 have been shown to mediate claudin-5 and occludin degradation, and play an important regulatory role in blood-brain barrier permeability. This study established a rat model of 1.5-hour middle cerebral artery occlusion with reperfusion. Protein expre...

journal_title：Neural regeneration research

authors： Xin H,Liang W,Mang J,Lin L,Guo N,Zhang F,Xu Z

更新日期：2012-11-05 00:00:00

abstract：:This study aimed to summarize therapy experience of carotid endarterectomy, carotid endarterectomy combined with Fogarty catheter embolectomy, and hybrid surgery for the treatment of extracranial internal carotid artery occlusion. The study included 65 patients with extracranial internal carotid artery occlusion who u...

journal_title：Neural regeneration research

authors： Jiao L,Song G,Hua Y,Ma Y,Chen Y,Wang Y,Ling F

更新日期：2013-08-15 00:00:00

abstract：:Although numerous studies have examined the neurotoxicity of acrylamide in adult animals, the effects on neuronal development in the embryonic and lactational periods are largely unknown. Thus, we examined the toxicity of acrylamide on neuronal development in the hippocampus of fetal rats during pregnancy. Sprague-Daw...

journal_title：Neural regeneration research

authors： Lai SM,Gu ZT,Zhao MM,Li XX,Ma YX,Luo L,Liu J

更新日期：2017-10-01 00:00:00

abstract：:A mixture of ibotenic acid and β-amyloid 1-42 was injected into the hippocampus of a rat model of Alzheimer's disease, followed by intragastric administration of a traditional Chinese medicine Buyuan Congnao decoction (main components included radix astragali, radix polygoni multiflori preparata, rhizoma acori talarin...

journal_title：Neural regeneration research

authors： Chen M,Wang J,Ming C

更新日期：2012-03-25 00:00:00

abstract：:The Na(+)-K(+)-Cl(-) cotransporter 1 and K(+)-Cl(-) cotransporter 2 regulate the levels of intracellular chloride in hippocampal cells. Impaired chloride transport by these proteins is thought to be involved in the pathophysiological mechanisms of mesial temporal lobe epilepsy. Imbalance in the relative expression of ...

journal_title：Neural regeneration research

authors： Cai X,Yang L,Zhou J,Zhu D,Guo Q,Chen Z,Chen S,Zhou L

更新日期：2013-02-25 00:00:00

abstract：:Aquaporin-4 regulates water molecule channels and is important in tissue regulation and water transportation in the brain. Upregulation of aquaporin-4 expression is closely related to cellular edema after early cerebral infarction. Cellular edema and aquaporin-4 expression can be determined by measuring cerebral infar...

journal_title：Neural regeneration research

authors： He ZP,Lu H

更新日期：2015-07-01 00:00:00

abstract：:We have previously shown that induction of ketosis by ketogenic diet (KD) conveyed neuroprotection following spinal cord injury in rodent models, however, clinical translation may be limited by the slow raise of ketone levels when applying KD in the acute post-injury period. Thus we investigated the use of exogenous k...

journal_title：Neural regeneration research

authors： Tan BT,Jiang H,Moulson AJ,Wu XL,Wang WC,Liu J,Plunet WT,Tetzlaff W

更新日期：2020-10-01 00:00:00

abstract：:Electroacupuncture has been shown to improve cerebral blood flow in animal models of stroke. However, it is unclear whether electroacupuncture alters miRNA expression in the cortex. In this study, we examined changes in the cerebral cortical miRNA profile, cerebral blood flow and neurological function induced by elect...

journal_title：Neural regeneration research

authors： Zheng HZ,Jiang W,Zhao XF,Du J,Liu PG,Chang LD,Li WB,Hu HT,Shi XM

更新日期：2016-12-01 00:00:00

abstract：:The G-protein-coupled purinergic receptor P2Y2 (P2RY2) plays an important role in the mechanism of atherosclerosis, which is relevant to ischemic stroke. This retrospective case-control study aimed to assess the relationship between P2RY2 gene polymorphisms and ischemic stroke risk in the northern Han Chinese populati...

journal_title：Neural regeneration research

authors： Yuan LY,He ZY,Li L,Wang YZ

更新日期：2019-03-01 00:00:00

abstract：:Cavernous nerve injury is the main cause of erectile dysfunction following radical prostatectomy. The recovery of erectile function following radical prostatectomy remains challenging. Our previous studies found that injecting adipose-derived stem cells (ADSCs) into the cavernosa could repair the damaged cavernous ner...

journal_title：Neural regeneration research

authors： Yang M,Sun JY,Ying CC,Wang Y,Guo YL

更新日期：2020-01-01 00:00:00

abstract：:Multiple mononeuropathy is an unusual form of peripheral neuropathy involving two or more nerve trunks. It is a syndrome with many different causes. We reviewed the clinical, electrophysiological and nerve biopsy findings of 14 patients who suffered from multiple mononeuropathy in our clinic between January 2009 and J...

journal_title：Neural regeneration research

authors： Zhang YS,Sun AP,Chen L,Dong RF,Zhong YF,Zhang J

更新日期：2015-01-01 00:00:00

abstract：:Astrocytes are specialized and most numerous glial cell type in the central nervous system and play important roles in physiology. Astrocytes are also critically involved in many neural disorders including focal ischemic stroke, a leading cause of brain injury and human death. One of the prominent pathological feature...

journal_title：Neural regeneration research

authors： Ding S

更新日期：2014-12-01 00:00:00

abstract：:Synaptosomal-associated protein-25 is an important factor for synaptic functions and cognition. In this study, subarachnoid hemorrhage models with spatial learning disorder were established through a blood injection into the chiasmatic cistern. Immunohistochemical staining and western blot analysis results showed that...

journal_title：Neural regeneration research

authors： Chen G,Hu T,Li Q,Li J,Jia Y,Wang Z

更新日期：2013-10-15 00:00:00

abstract：:Following spinal cord ischemia/reperfusion injury, an endogenous damage system is immediately activated and participates in a cascade reaction. It is difficult to interpret dynamic changes in these pathways, but the examination of the transcriptome may provide some information. The transcriptome reflects highly dynami...

journal_title：Neural regeneration research

authors： Qi ZP,Xia P,Hou TT,Li DY,Zheng CJ,Yang XY

更新日期：2016-03-01 00:00:00

abstract：:The blood brain barrier represents a formidable obstacle for the transport of most systematically administered neurodiagnostics and neurotherapeutics to the brain. Phage display is a high throughput screening strategy that can be used for the construction of nanomaterial peptide libraries. These libraries can be scree...

journal_title：Neural regeneration research

authors： Bakhshinejad B,Karimi M,Khalaj-Kondori M

更新日期：2015-06-01 00:00:00

abstract：:Extracellular vesicles, including exosomes and microvesicles, play a fundamental role in the activity of the nervous system, participating in signal transmission between neurons and providing the interaction of central nervous system with all body systems. In many neurodegenerative diseases, neurons pack toxic substan...

journal_title：Neural regeneration research

authors： Shaimardanova AA,Solovyeva VV,Chulpanova DS,James V,Kitaeva KV,Rizvanov AA

更新日期：2020-04-01 00:00:00

abstract：:Traumatic brain injury (TBI) is a major health problem worldwide. Following primary mechanical insults, a cascade of secondary injuries often leads to further neural tissue loss. Thus far there is no cure to rescue the damaged neural tissue. Current therapeutic strategies primarily target the secondary injuries focusi...

journal_title：Neural regeneration research

authors： Wurzelmann M,Romeika J,Sun D

更新日期：2017-01-01 00:00:00

abstract：:Acute brain injury caused by subarachnoid hemorrhage is the major cause of poor prognosis. The pathology of subarachnoid hemorrhage likely involves major morphological changes in the microcirculation. However, previous studies primarily used fixed tissue or delayed injury models. Therefore, in the present study, we us...

journal_title：Neural regeneration research

authors： Yang XM,Chen XH,Lu JF,Zhou CM,Han JY,Chen CH

更新日期：2018-03-01 00:00:00

abstract：:In this study, rats were put into traumatic brain injury-induced coma and treated with median nerve electrical stimulation. We explored the wake-promoting effect, and possible mechanisms, of median nerve electrical stimulation. Electrical stimulation upregulated the expression levels of orexin-A and its receptor OX1R ...

journal_title：Neural regeneration research

authors： Feng Z,Zhong YJ,Wang L,Wei TQ

更新日期：2015-04-01 00:00:00