Abstract:
:An accurate and effective neurological evaluation is indispensable in the treatment and rehabilitation of traumatic brain injury. However, most of the existing evaluation methods in basic research and clinical practice are not objective or intuitive for assessing the neurological function of big animals, and are also difficult to use to qualify the extent of damage and recovery. In the present study, we established a big animal model of traumatic brain injury by impacting the cortical motor region of beagles. At 2 weeks after successful modeling, we detected neurological deficiencies in the animal model using a series of techniques, including three-dimensional motion capture, electromyogram and ground reaction force. These novel technologies may play an increasingly important role in the field of traumatic brain injury diagnosis and rehabilitation in the future. The experimental protocol was approved by the Animal Care and Use Committee of Logistics University of People's Armed Police Force (approval No. 2017-0006.2).
journal_name
Neural Regen Resjournal_title
Neural regeneration researchauthors
Jiang JP,Niu XG,Dai C,Ma K,Xu HY,Cheng SX,Zhang ZW,Duan F,Zhu X,Wang YT,Chen XY,Zhang Sdoi
10.4103/1673-5374.250578subject
Has Abstractpub_date
2019-06-01 00:00:00pages
991-996issue
6eissn
1673-5374issn
1876-7958pii
NeuralRegenRes_2019_14_6_991_250578journal_volume
14pub_type
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