Abstract:
:In the past decade, lung ultrasound (LUS) B-lines and serum Krebs von den Lungen-6 (KL-6) antigen have been recognized as biomarkers of the connective tissue disease-associated interstitial lung diseases (CTD-ILDs). Robust data have demonstrated that B-lines total numbers and KL-6 levels are correlated with high-resolution computed tomography findings, pulmonary function test, and some clinical parameters in CTD-ILDs. However, limited data are available regarding the use of these two biomarkers to follow CTD-ILDs. Herein, we report a case with anti-melanoma differentiation-associated gene 5 antibody-positive clinically amyopathic dermatomyositis-associated ILD, successfully treated with high-dose methylprednisolone, cyclophosphamide, intravenous immunoglobulin, pirfenidone, and followed using lung ultrasound and KL-6.
journal_name
Clin Rheumatoljournal_title
Clinical rheumatologyauthors
Wang Y,Chen S,Lin Z,Lin J,Xie X,Lin Q,Du G,Huang X,Matucci-Cerinic M,Furst DEdoi
10.1007/s10067-019-04462-zsubject
Has Abstractpub_date
2019-05-01 00:00:00pages
1433-1436issue
5eissn
0770-3198issn
1434-9949pii
10.1007/s10067-019-04462-zjournal_volume
38pub_type
杂志文章abstract::Knee osteoarthritis is a common joint problem leading to an increase of pain and a loss of function in older individuals. The main objective of this study was to evaluate if a participant who was randomly assigned to his preferred group improved his adherence to an effective walking program compared to a participant w...
journal_title:Clinical rheumatology
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