Abstract:
:To screen Bacillus clausii UBBC07 as a putative probiotic strain and to examine the protective effect of probiotic-B. clausii UBBC07 spore on uremia on rats induced by acetaminophen. In vitro tests performed to screen potential probiotic strains were gastric and bile acid resistance and ability to reduce pathogen adhesion to surfaces. An in vivo study was performed on rats (n = 18) which were randomly divided into three groups: group I, control-receives normal food and water, groups II and III receive acetaminophen i.p. at the dose of 550 mg/kg/day for 10 days, groups III was treated with B. clausii UBBC07 at a dose of 1 × 109 CFU/day for 15 days. Urea, creatinine, malondialdehyde (MDA), and GSH levels and antioxidant enzymes like super oxide dismutase (SOD) and catalase activity were considered to analyze renal failure. Plasma urea and creatinine levels (p < 0.05) significantly increase and SOD, catalase, and GSH activity level significantly decrease in group II as compared with the control group. After treatment with probiotic, there was a significant increase in SOD and catalase (p < 0.05) and a significant decrease in serum urea, creatinine, and MDA (p < 0.05) in group III in response to group II. The results also revealed that probiotic was able to tolerate pH 3.0-9.0 and 0.3% bile salt. The present study suggests that B. clausii UBBC07 could be used as a novel alternative natural therapy for uremia, a major syndrome of CKD.
journal_name
Probiotics Antimicrob Proteinsjournal_title
Probiotics and antimicrobial proteinsauthors
Patel C,Patel P,Acharya Sdoi
10.1007/s12602-019-09540-xsubject
Has Abstractpub_date
2020-03-01 00:00:00pages
253-258issue
1eissn
1867-1306issn
1867-1314pii
10.1007/s12602-019-09540-xjournal_volume
12pub_type
杂志文章abstract::Plantaricin 423, produced by Lactobacillus plantarum 423, was encapsulated in nanofibers that were produced by the electrospinning of 18% (w/v) polyethylene oxide (200 000 Da). The average diameter of the nanofibers was 288 nm. Plantaricin 423 activity decreased from 51 200 AU/ml to 25 600 AU/ml and from 204 800 AU/ml...
journal_title:Probiotics and antimicrobial proteins
pub_type: 杂志文章
doi:10.1007/s12602-009-9024-9
更新日期:2010-03-01 00:00:00
abstract::Information regarding cellular anti-senescence attributes of probiotic bacteria vis-à-vis modulation of senescence-associated secretory phenotype (SASP) and mTOR signaling is very limited. The present study assessed anti-senescence potential of secretory metabolites of probiotic Lactobacillus fermentum (Lact. fermentu...
journal_title:Probiotics and antimicrobial proteins
pub_type: 杂志文章
doi:10.1007/s12602-019-09576-z
更新日期:2020-06-01 00:00:00
abstract::The fate of dietary protein in the gut is determined by microbial and host digestion and utilization. Fermentation of proteins generates bioactive molecules that have wide-ranging health effects on the host. The type of protein can affect amino acid absorption, with animal proteins generally being more efficiently abs...
journal_title:Probiotics and antimicrobial proteins
pub_type: 杂志文章
doi:10.1007/s12602-020-09656-5
更新日期:2020-12-01 00:00:00
abstract::Food-grade yeasts make significant contributions to flavor development in fermented foods. Some yeast species also inhibit undesirable bacteria, yeasts and molds, apparently by producing antimicrobial compounds called mycocins. The aim of this study was to evaluate the ability of wild yeasts, isolated from raw milk an...
journal_title:Probiotics and antimicrobial proteins
pub_type: 杂志文章
doi:10.1007/s12602-012-9109-8
更新日期:2013-03-01 00:00:00
abstract::A specific strain of naturally occurring oral lactobacilli was isolated and identified based on morphological, biochemical, and 16S rRNA gene sequencing. The phylogenetic affiliation of the isolate confirmed that the NK02 strain had close association with the Lactobacillus salivarius. An effective mouthwash was develo...
journal_title:Probiotics and antimicrobial proteins
pub_type: 杂志文章,随机对照试验
doi:10.1007/s12602-017-9296-4
更新日期:2018-09-01 00:00:00
abstract::In this paper, the antibacterial effects of the Bacillus amyloliquefaciens-produced bacteriocin subtilosin, both alone and in combination with curcumin, ε-poly-L-lysine (poly-lysine), or zinc lactate, were examined against Listeria monocytogenes. Results indicated that subtilosin inhibits both of the studied bacterial...
journal_title:Probiotics and antimicrobial proteins
pub_type: 杂志文章
doi:10.1007/s12602-010-9042-7
更新日期:2010-12-01 00:00:00
abstract::Newly hatched broiler chickens are the most susceptible to Salmonella infections, especially during the first 24 h. At this age, the gut microbiome is not fully developed and offers little protection in the form of competitive exclusion. In this study, one group of newly hatched, Salmonella-free broilers were colonise...
journal_title:Probiotics and antimicrobial proteins
pub_type: 杂志文章
doi:10.1007/s12602-019-09593-y
更新日期:2020-09-01 00:00:00
abstract::The study reports the growth, acidification and proteolysis of eight selected lactic acid bacteria in skim and soy milk. Angiotensin-converting enzyme inhibition and antimicrobial profiles of skim and soy milk fermented by the lactic acid bacteria were also determined. Among eight lactic cultures (S. thermophilus MD2,...
journal_title:Probiotics and antimicrobial proteins
pub_type: 杂志文章
doi:10.1007/s12602-017-9279-5
更新日期:2018-06-01 00:00:00
abstract::Twenty-nine Lactobacillus plantarum strains isolated from different types of Polish regional cheeses (Oscypek and Korycinski) were assessed for selected probiotic properties and anti-staphylococcal activity. Most of the tested L. plantarum strains were considered safe. Whole bacterial cultures (WBC) and cell-free supe...
journal_title:Probiotics and antimicrobial proteins
pub_type: 杂志文章
doi:10.1007/s12602-019-09587-w
更新日期:2020-09-01 00:00:00
abstract::The aim of this study was to investigate the effects of probiotic and synbiotic supplementation on serum inflammatory markers, endotoxin, and anti-HSP70 in hemodialysis (HD) patients. This study was a randomized, double-blind, placebo-controlled trial. Seventy-five hemodialysis patients who met the inclusion and exclu...
journal_title:Probiotics and antimicrobial proteins
pub_type: 杂志文章
doi:10.1007/s12602-018-9509-5
更新日期:2020-03-01 00:00:00
abstract::This review focuses on the structure and mode-of-action of the two-peptide (class-IIb) bacteriocins that consist of two different peptides whose genes are next to each other in the same operon. Optimal antibacterial activity requires the presence of both peptides in about equal amounts. The two peptides are synthesize...
journal_title:Probiotics and antimicrobial proteins
pub_type: 杂志文章
doi:10.1007/s12602-009-9021-z
更新日期:2010-03-01 00:00:00
abstract::The reduction in the use of antibiotics in the poultry industry has considerably increased the appearance of Clostridium perfringens (CP)-induced subclinical necrotic enteritis (SNE), forcing researchers to search alternatives to antibiotic growth promoters (AGP) like probiotics. This study aimed to investigate the ef...
journal_title:Probiotics and antimicrobial proteins
pub_type: 杂志文章
doi:10.1007/s12602-019-09597-8
更新日期:2020-09-01 00:00:00
abstract::Lipopolysaccharide (LPS) is a toxic and immunogenic agent for human. Additionally, LPS is a good target for some antimicrobial compounds, including antimicrobial peptides (AMPs). LPS-binding peptides (LBPs) can recognize and neutralize LPS. Rabbit and human cathelicidins are AMPs with LPS-binding activity. In this stu...
journal_title:Probiotics and antimicrobial proteins
pub_type: 杂志文章
doi:10.1007/s12602-020-09648-5
更新日期:2020-12-01 00:00:00
abstract::The wide spread of antimicrobial resistance has urged the need of alternative therapeutic approach. In this context, probiotic lactobacilli have been reported for the prevention and treatment of many gastrointestinal and urogenital infections. However, very little is known about their antagonistic activity against ski...
journal_title:Probiotics and antimicrobial proteins
pub_type: 杂志文章
doi:10.1007/s12602-013-9137-z
更新日期:2013-09-01 00:00:00
abstract::Antimicrobial peptides (AMPs) are compounds widely distributed in nature that display activity against a broad spectrum of pathogens. Amphibian skin, as an organ rich in pharmacologically active peptides, appears to be an interesting source of novel AMPs. Aurein 1.2 (GLFDIIKKIAESF-NH2) is a short 13-residue antimicrob...
journal_title:Probiotics and antimicrobial proteins
pub_type: 杂志文章
doi:10.1007/s12602-018-9501-0
更新日期:2019-09-01 00:00:00
abstract::In this work, we performed the rational design of a cationic antimicrobial peptide, GIBIMPY4, using the software DEPRAMPs developed at the GIBIM research group. GIBIMPY4 has a length of 17 amino acids, it is amphipathic, its structure is α-helix and it has a net charge of (+5). Solid-phase peptide synthesis was perfor...
journal_title:Probiotics and antimicrobial proteins
pub_type: 杂志文章
doi:10.1007/s12602-016-9219-9
更新日期:2016-09-01 00:00:00
abstract::The present study was conducted to assess the effects of combined and singular dietary administration of PrimaLac® and potassium diformate (KDF) on growth performance, feed utilization, digestive enzymes activity, and some physiological parameters of rainbow trout (Oncorhynchus mykiss) juvenile. Three hundred sixty ra...
journal_title:Probiotics and antimicrobial proteins
pub_type: 杂志文章
doi:10.1007/s12602-019-9523-2
更新日期:2020-03-01 00:00:00
abstract::The bactericidal activities of cattle and swine platelet microbicidal proteins (PMPs) with their comparison with human PMP were studied. Activities of PMP were tested against Bacillus subtilis, Bacillus cereus, Staphylococcus aureus, Staphylococcus epidermidis, Micrococcus lysodeikticus and Escherichia coli. B. subtil...
journal_title:Probiotics and antimicrobial proteins
pub_type: 杂志文章
doi:10.1007/s12602-009-9016-9
更新日期:2009-12-01 00:00:00
abstract::Oysters hold a unique place within the field of aquaculture as one of the only organisms that is regularly shipped live to be consumed whole and raw. The microbiota of oysters is capable of adapting to a wide range of environmental conditions within their dynamic estuarine environments; however, human aquaculture prac...
journal_title:Probiotics and antimicrobial proteins
pub_type: 杂志文章,评审
doi:10.1007/s12602-019-09629-3
更新日期:2020-06-01 00:00:00
abstract::A Bacillus-based direct-fed microbial (DFM), Omni-BosCB™, added to an electrolyte was evaluated as a therapy for scours. Fecal shedding of presumptive Clostridium perfringens at day 7 was reduced in scouring calves treated with electrolyte plus DFM compared to scouring calves treated with electrolyte alone. Total ther...
journal_title:Probiotics and antimicrobial proteins
pub_type: 杂志文章
doi:10.1007/s12602-008-9004-5
更新日期:2009-06-01 00:00:00
abstract::Oxidative stress plays an important role in exacerbating neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and Huntington's disease. In a previous study, Lactobacillus plantarum 200655 was shown to possess probiotic and antioxidant potential. The current study aimed to evaluate the neuropro...
journal_title:Probiotics and antimicrobial proteins
pub_type: 杂志文章
doi:10.1007/s12602-020-09740-w
更新日期:2021-01-17 00:00:00
abstract::The purpose of this article is to reveal the role of the lactic acid bacteria (LAB) in the beebread transformation/preservation, biochemical properties of 25 honeybee endogenous LAB strains, particularly: antifungal, proteolytic, and amylolytic activities putatively expressed in the beebread environment have been stud...
journal_title:Probiotics and antimicrobial proteins
pub_type: 杂志文章
doi:10.1007/s12602-017-9379-2
更新日期:2018-12-01 00:00:00
abstract::It is well established that bacteria communicate between each other by using different mechanisms; among which, quorum sensing (QS) is the best known one. Indeed, intra- and intercellular communications of microorganisms, as well as the regulation of metabolism and reaction to the surrounding environmental conditions,...
journal_title:Probiotics and antimicrobial proteins
pub_type: 杂志文章,评审
doi:10.1007/s12602-019-09555-4
更新日期:2020-03-01 00:00:00
abstract::The administration of probiotics is a promising approach to reduce the prevalence of colon cancer, a multifactorial disease, with hereditary factors, as well as environmental lifestyle-related risk factors. Biogenic polyamines, putrescine, spermidine, and spermine are small cationic molecules with great roles in cell ...
journal_title:Probiotics and antimicrobial proteins
pub_type: 杂志文章
doi:10.1007/s12602-017-9253-2
更新日期:2017-06-01 00:00:00
abstract::Probiotics offer numerous health benefits, including digestive and immune health. Improved digestive health is linked to a more efficient absorption of important nutrients from our diet. This review focused on the rationale of using the probiotic Bacillus coagulans GBI-30, 6086 to aid protein absorption and utilizatio...
journal_title:Probiotics and antimicrobial proteins
pub_type: 杂志文章,评审
doi:10.1007/s12602-017-9354-y
更新日期:2018-12-01 00:00:00
abstract::The aim of this work is to characterize the potential probiotic properties of 14 antifungal Lactobacillus strains isolated from traditional fermenting Moroccan green olives. The molecular identification of strains indicated that they are composed of five Lactobacillus brevis, two Lactobacillus pentosus, and seven Lact...
journal_title:Probiotics and antimicrobial proteins
pub_type: 杂志文章
doi:10.1007/s12602-019-09543-8
更新日期:2020-06-01 00:00:00
abstract::Thaumatin-like proteins (TLPs) are the products of a large, highly complex gene family involved in host defense. TLPs also belong to the pathogenesis-related family 5 (PR-5) of plant defense proteins. Most TLPs exhibit potential antifungal activities, and their accumulation in the plant is related to many physiologica...
journal_title:Probiotics and antimicrobial proteins
pub_type: 杂志文章
doi:10.1007/s12602-018-9422-y
更新日期:2019-03-01 00:00:00
abstract::In this study, we have investigated the effect of probiotic Lactobacillus helveticus CD6 supplemented into simple laboratory fish feed (LFF) and complex, multi-ingredient market fish feed (MFF) on growth performance, antioxidant levels, and essential trace element absorption in goldfish (Carassius auratus). Twenty-fou...
journal_title:Probiotics and antimicrobial proteins
pub_type: 杂志文章
doi:10.1007/s12602-018-9428-5
更新日期:2019-06-01 00:00:00
abstract::Emerging evidence suggests that probiotic therapy can play a role in the prevention and management of oral inflammatory diseases through immunomodulation and down-regulation of the inflammatory cascade. The aim of this in vitro study was to investigate the viability of human gingival fibroblasts (HGF) and its producti...
journal_title:Probiotics and antimicrobial proteins
pub_type: 杂志文章
doi:10.1007/s12602-016-9246-6
更新日期:2017-09-01 00:00:00
abstract::The original version of this article contained mistakes, and the authors would like to correct them. The correct details are given below. ...
journal_title:Probiotics and antimicrobial proteins
pub_type: 已发布勘误
doi:10.1007/s12602-018-9412-0
更新日期:2019-06-01 00:00:00