Delirium in an Acute Stroke Setting, Occurrence, and Risk Factors.

Abstract:

:Background and Purpose- Delirium is a common and serious complication of acute illness. We describe delirium occurrence in an unselected, acute stroke population. Methods- We collected data from consecutive stroke admissions. We performed comprehensive cognitive assessment within the first week including Diagnostic Statistical Manual-5-based delirium diagnosis. We reported proportion with delirium and the clinical and demographic associations with delirium using multiple logistic regression. Results- Of 708 patients, median age of 71 years (interquartile range, 59-80), we recorded delirium in 187 of 708 (26.4%; 95% CI, 23.0-30.0). Across 395 patients with complete risk factor data (105 delirium), factors independently associated with delirium were: age (odds ratio, 1.05; 95% CI, 1.03-1.08), drug/alcohol misuse (odds ratio, 2.64; 95% CI, 1.10-6.26), and stroke severity (odds ratio, 1.22; 95% CI, 1.14-1.31). Conclusions- Delirium is common in acute stroke, affecting 1 in 4. It may be possible to predict those at risk using prestroke and stroke-specific factors. Clinical Trial Registration- URL: researchregistry.com. Protocol: 1147.

journal_name

Stroke

journal_title

Stroke

authors

Shaw R,Drozdowska B,Taylor-Rowan M,Elliott E,Cuthbertson G,Stott DJ,Quinn TJ

doi

10.1161/STROKEAHA.119.025993

subject

Has Abstract

pub_date

2019-11-01 00:00:00

pages

3265-3268

issue

11

eissn

0039-2499

issn

1524-4628

journal_volume

50

pub_type

临床试验,杂志文章

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