Effects of aging and hypertension on endothelium-dependent vascular relaxation in rat carotid artery.

abstract：BACKGROUND AND PURPOSE:Increased mean platelet volume (MPV), indicating higher platelet reactivity, is associated with an increased risk of myocardial infarction. Higher levels of MPV have been found in patients with acute ischemic stroke than in control subjects. Data from smaller studies regarding an association betw...

journal_title：Stroke

authors： Greisenegger S,Endler G,Hsieh K,Tentschert S,Mannhalter C,Lalouschek W

更新日期：2004-07-01 00:00:00

abstract：:Ischemia due to middle cerebral artery occlusion was studied in 29 rats from 1 to 24 hours after occlusion using magnetic resonance imaging. Images were made before and after the injection of a superparamagnetic iron oxide compound, AMI-25. Subtraction images demonstrated the region of perfusion deficit as early as 1 ...

journal_title：Stroke

authors： Bradley RH,Kent TA,Eisenberg HM,Quast MJ,Ward GA,Campbell GA,Hillman G

更新日期：1989-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Arterial stiffness is associated with an increased risk of myocardial infarction and stroke, independent of classical vascular risk factors. Vascular factors and stroke are associated with cognitive function and dementia. We examined whether arterial stiffness was independently associated with co...

journal_title：Stroke

authors： Poels MM,van Oijen M,Mattace-Raso FU,Hofman A,Koudstaal PJ,Witteman JC,Breteler MM

更新日期：2007-03-01 00:00:00

abstract：:Background and Purpose- Enhancement of erythrophagocytosis by macrophages in a timely manner can limit the toxic effects of erythrocyte metabolites and promote brain recovery after intracerebral hemorrhage (ICH). In the current study, we investigated the therapeutic effect of retinoid X receptor agonist, bexarotene, i...

journal_title：Stroke

authors： Chang CF,Massey J,Osherov A,Angenendt da Costa LH,Sansing LH

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The composition of carotid atherosclerosis was visualized by using 3D MRI at high resolution with 200-micrometer (3) voxels. Magnetic resonance signal characteristics were correlated with plaque components, including collagenous cap, necrotic core, and calcification, to define resolution and othe...

journal_title：Stroke

authors： Coombs BD,Rapp JH,Ursell PC,Reilly LM,Saloner D

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Subarachnoid hemorrhage (SAH) caused by ruptured intracranial aneurysm affects approximately 16 000 Americans annually, and almost 40% of affected patients die within 30 days despite the best current therapy. Prevention of SAH is therefore of paramount importance. We present a preliminary analysi...

journal_title：Stroke

authors： Kissela BM,Sauerbeck L,Woo D,Khoury J,Carrozzella J,Pancioli A,Jauch E,Moomaw CJ,Shukla R,Gebel J,Fontaine R,Broderick J

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Persons with early stages of chronic kidney disease, defined by a decreased glomerular filtration rate (GFR), have an increased risk of cardiovascular disease. It is unclear whether decreased GFR is a risk factor for stroke. We assessed the association between GFR and stroke in a prospective popu...

journal_title：Stroke

authors： Bos MJ,Koudstaal PJ,Hofman A,Breteler MM

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The pathophysiology of borderzone infarcts is not well understood. We investigated whether combined diffusion-weighted imaging (DWI) and perfusion-weighted imaging (PWI) could identify pathophysiologically meaningful categories of borderzone infarcts. METHODS:Seventeen patients with borderzone i...

journal_title：Stroke

authors： Chaves CJ,Silver B,Schlaug G,Dashe J,Caplan LR,Warach S

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:On the assumption that the majority of lacunes are caused by small-vessel diseases and that pial artery infarcts arise from cardio-embolic or large-vessel diseases, 194 patients from the Berlin Cerebral Ischemia Data Bank with either lacunar or pial artery infarcts were analyzed for the frequency...

journal_title：Stroke

authors： Mast H,Thompson JL,Völler H,Mohr JP,Marx P

更新日期：1994-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Transcatheter closure of patent foramen ovale (PFO) has been reported to improve migraine in patients with cerebrovascular disorders in noncontrolled studies. The aim of the study was to compare the course of migraine assessed prospectively over a 12-month period in symptomatic (for cerebrovascul...

journal_title：Stroke

authors： Anzola GP,Frisoni GB,Morandi E,Casilli F,Onorato E

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The Mechanical Embolus Removal in Cerebral Ischemia (MERCI) and Multi MERCI trials evaluated the safety and efficacy of thrombectomy in the treatment of intracranial arterial occlusions within 8 hours of symptom onset. We sought to determine the predictors of clinical and angiographic outcomes in...

journal_title：Stroke

authors： Nogueira RG,Liebeskind DS,Sung G,Duckwiler G,Smith WS,MERCI.,Multi MERCI Writing Committee.

更新日期：2009-12-01 00:00:00

abstract：:In a randomized pilot study we compared the efficacy of temporary anticoagulation with intravenous heparin sodium to the efficacy of aspirin in preventing cerebral infarction in hospitalized patients with recent (less than 7 days) transient ischemic attacks (TIAs). Fifty-five patients (33 men, 22 women) aged 36-81 (me...

journal_title：Stroke

authors： Biller J,Bruno A,Adams HP Jr,Godersky JC,Loftus CM,Mitchell VL,Banwart KJ,Jones MP

更新日期：1989-04-01 00:00:00

abstract：:During perinatal asphyxia, cerebral blood flow is markedly reduced in the gray and white matter of the telencephalon. Since previous work has implicated prostaglandins in the control of blood flow, we tested the hypothesis that a thromboxane synthesis inhibitor would improve cerebral blood flow and blunt the metabolic...

journal_title：Stroke

authors： Ment LR,Stewart WB,Petroff OA,Duncan CC

更新日期：1989-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Sonic hedgehog (Shh) protein is required for the maintenance of neural progenitor cells (NPCs) in the embryonic and adult hippocampus. Brain ischemia causes increased proliferation of hippocampal NPCs. We therefore examined whether Shh regulates the increase in proliferation of NPCs after ischemi...

journal_title：Stroke

authors： Sims JR,Lee SW,Topalkara K,Qiu J,Xu J,Zhou Z,Moskowitz MA

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There are few studies analyzing stroke in women, taking into account the vascular risk factors, cause of stroke, clinical picture, and outcome. The purpose of this study was to analyze possible sex differences in patients suffering first-ever acute stroke. METHODS:From December 1995 to January 2...

journal_title：Stroke

authors： Roquer J,Campello AR,Gomis M

更新日期：2003-07-01 00:00:00

abstract：:Background and Purpose- Aneurysmal subarachnoid hemorrhage (aSAH) has a high healthcare cost burden. Methods- We performed a cross-sectional analysis of the costs of clipping and coiling of aSAH using the National Inpatient Sample and Vizient databases. We conducted multiple regression analyses to estimate national co...

journal_title：Stroke

authors： Yoon S,Yoon JC,Winkler E,Liu C,Lawton MT

更新日期：2018-12-03 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an inherited systemic microangiopathy with prevalently cerebral manifestations. Among the causes of death, sudden unexpected death seems to occur in a significant number of CADASIL patients. Be...

journal_title：Stroke

authors： Rufa A,Guideri F,Acampa M,Cevenini G,Bianchi S,De Stefano N,Stromillo ML,Federico A,Dotti MT

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Patients with arteriovenous malformations are younger individuals who are at risk of a stroke or have experienced one. Our objective was to determine these patients' perceptions of quality of life with a stroke by eliciting utility values. METHODS:Utility values were obtained with the standard g...

journal_title：Stroke

authors： Shin AY,Porter PJ,Wallace MC,Naglie G

更新日期：1997-12-01 00:00:00

abstract：:Background and Purpose- Prehospital routing algorithms for patients with suspected stroke because of large vessel occlusions should account for likelihood of benefit from endovascular therapy (EVT), risk of alteplase delays, and transport times. We built a mathematical model to give a real-time, location-based optimal...

journal_title：Stroke

authors： Ali A,Zachrison KS,Eschenfeldt PC,Schwamm LH,Hur C

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Elevated cardiac troponin is a marker of cardiac disease and has been recently shown to be associated with embolic stroke risk. We hypothesize that early elevated troponin levels in the acute stroke setting are more prevalent in patients with embolic stroke subtypes (cardioembolic and embolic str...

journal_title：Stroke

authors： Yaghi S,Chang AD,Ricci BA,Jayaraman MV,McTaggart RA,Hemendinger M,Narwal P,Dakay K,Mac Grory B,Cutting SM,Burton TM,Song C,Mehanna E,Siket M,Madsen TE,Reznik M,Merkler AE,Lerario MP,Kamel H,Elkind MSV,Furie KL

更新日期：2018-01-01 00:00:00

abstract：:Background and Purpose- Hyperglycemia is a negative prognostic factor after acute ischemic stroke but is not known whether glucose is associated with the effects of endovascular thrombectomy (EVT) in patients with large-vessel stroke. In a pooled-data meta-analysis, we analyzed whether serum glucose is a treatment mod...

journal_title：Stroke

authors： Chamorro Á,Brown S,Amaro S,Hill MD,Muir KW,Dippel DWJ,van Zwam W,Butcher K,Ford GA,den Hertog HM,Mitchell PJ,Demchuk AM,Majoie CBLM,Bracard S,Sibon I,Jadhav AP,Lara-Rodriguez B,van der Lugt A,Osei E,Renú A,Richard

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Administration of histamine receptor antagonists has been reported to produce contradictory results, either reducing or increasing neural damage induced by ischemia. In this study, we investigated the neuroprotective effects of histamine H2-receptor antagonists in an "in vitro" model of ischemia....

journal_title：Stroke

authors： Malagelada C,Xifró X,Badiola N,Sabrià J,Rodríguez-Alvarez J

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Aneurysmal subarachnoid hemorrhage (SAH) is a cerebrovascular disease with a high mortality rate and severe disability. Longitudinal studies investigating health-economic costs in SAH are scare and only one of them analyzed cost-driving factors. The objective was to evaluate first-year costs in G...

journal_title：Stroke

authors： Dodel R,Winter Y,Ringel F,Spottke A,Gharevi N,Müller I,Klockgether T,Schramm J,Urbach H,Meyer B

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The present study investigated the influence of the antiplatelet agent acetylsalicylic acid (ASA) on cerebral microembolism as detected by transcranial Doppler sonography (TCD). METHODS:Nine patients with recent transient ischemic attack or minor stroke of arterial origin were investigated. Eigh...

journal_title：Stroke

authors： Goertler M,Baeumer M,Kross R,Blaser T,Lutze G,Jost S,Wallesch CW

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Treatment of stroke patients in specialized stroke units has become more frequent, yet the effect of this treatment has not been determined. METHODS:In a community-based, prospective, and consecutive study of 1241 unselected acute stroke patients, we compared outcome of stroke treatment between ...

journal_title：Stroke

authors： Jørgensen HS,Nakayama H,Raaschou HO,Larsen K,Hübbe P,Olsen TS

更新日期：1995-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Attained height, an indicator of genetic potential and childhood growth environment, is inversely associated with stroke, but the mechanisms are poorly understood. We investigated whether childhood height and growth are associated with ischemic stroke (IS) and intracerebral hemorrhage (ICH). MET...

journal_title：Stroke

authors： Gjærde LK,Truelsen TC,Baker JL

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Nimodipine, a calcium antagonist, has been reported to have beneficial effects in acute ischemic infarction. Some calcium channel antagonists have antiplatelet effects. We investigated the effect of oral nimodipine on platelet function in healthy volunteers. METHODS:Twelve healthy volunteers (6 ...

journal_title：Stroke

authors： Feinberg WM,Bruck DC

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Virtual reality (VR) is a new promising computer-assisted technology to promote motor recovery in stroke patients. VR-induced neuroplasticity supporting locomotor recovery is not known. We investigated the effects of VR intervention on cortical reorganization and associated locomotor recovery in ...

journal_title：Stroke

authors： You SH,Jang SH,Kim YH,Hallett M,Ahn SH,Kwon YH,Kim JH,Lee MY

更新日期：2005-06-01 00:00:00

abstract：:Background and Purpose- The impact of a mobile stroke unit (MSU) on access to intraarterial thrombectomy (IAT) is a prespecified BEST-MSU substudy (Benefits of Stroke Treatment Delivered Using a Mobile Stroke Unit Compared to Standard Management by Emergency Medical Services). On the MSU, IAT decision-making steps, su...

journal_title：Stroke

authors： Czap AL,Grotta JC,Parker SA,Yamal JM,Bowry R,Sheth SA,Rajan SS,Hwang H,Singh N,Bratina P,Bryndziar T,Alexandrov AV,Alexandrov AW,Dusenbury W,Swatzell V,Jones W,Ackerson K,Schimpf B,Wright P,Jagolino-Cole AL

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The lipophilic calcium channel antagonist flunarizine has been demonstrated to be neuroprotective in several models of cerebral ischemia. Ischemic spinal cord injury may have a similar pathophysiology and hence may respond in a similar fashion. This study was designed to investigate the effects o...

journal_title：Stroke

authors： Johnson SH,Kraimer JM,Graeber GM

更新日期：1993-10-01 00:00:00