Abstract:
BACKGROUND:This study aimed to evaluate, histomorphometrically, the use of collagen matrix (CM) and/or enamel matrix derivative (EMD) for the treatment of dehiscence-type recession defects in minipigs. METHODS:Eight healthy, male, young BR-1 minipigs, with no periodontal disease were treated. Bilateral dehiscence-type defects were surgically created on the buccal of the mandibular premolars (PI and PII). After 30 days, the defects were randomly assigned to four groups: coronally advanced flap (CAF); CAF + CM; CAF + EMD; and CAF + CM + EMD (split-mouth design). The evaluated parameters (mm): total defect length; new cementum (NC); new bone (NB); gingival margin position; total epithelium length; epithelium on the root; connective tissue adaptation; and soft tissue thickness (STT). RESULTS:The EMD-treated groups showed a superior length of NC [4.13 ± 1.22 (CAF + EMD); 3.95 ± 1.11 (CAF + CM + EMD); 2.94 ± 0.77 (CAF + CM); 2.72 ± 0.81 (CAF), P = 0.02] and NB [3.21 ± 0.68 (CAF + CM + EMD); 3.01 ± 0.56 (CAF + EMD); 2.15 ± 0.47 (CAF + CM); 2.29 ± 0.82 (CAF), P = 0.005]. The CAF and CAF + CM groups showed a superior epithelial length when compared to EMD-treated groups after 3 months. A superior STT was observed for CAF + CM + EMD group (1.5 ± 0.33) when compared with the other groups [1.09 ± 0.26 (CAF + EMD); 1.04 ± 0.34 (CAF + CM); and 1.14 ± 0.29 (CAF), P = 0.03]. CONCLUSION(S):The results of the present study indicate that EMD application, irrespective of the combination with CM, may improve the periodontal regeneration of dehiscence-type defects in this animal model.
journal_name
J Periodontoljournal_title
Journal of periodontologyauthors
França-Grohmann IL,Sangiorgio JPM,Bueno MR,Casarin RCV,Silvério Ruiz KG,Nociti FH Jr,Casati MZ,Sallum EAdoi
10.1002/JPER.19-0107subject
Has Abstractpub_date
2020-07-01 00:00:00pages
967-974issue
7eissn
0022-3492issn
1943-3670journal_volume
91pub_type
杂志文章abstract::A study was done in an attempt to develop a simple test for the severity of periodontal disease. Gingival fluid collected on filter paper was tested for protein content, and the resulting color was compared to standard color filters. Tissue was excised and prepared for histologic examination. The inflammatory cell inf...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1978.49.8.391
更新日期:1978-08-01 00:00:00
abstract:BACKGROUND:Morning breath odor is an often-encountered complaint. This double-blind, crossover, randomized study aimed to examine the bad breath-inhibiting effect of 3 commercially available mouthrinses on morning halitosis during an experimental period of 12 days without mechanical plaque control. METHODS:Twelve medi...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.2000.72.9.1183
更新日期:2001-09-01 00:00:00
abstract::Few scientific investigations have addressed the ability of mouthrinses to reduce oral malodor for periods longer than 3 hours. In the present report, we have employed simple, recently described techniques to assess the day-long reduction in oral malodor of a novel 2-phase oil:water mouthrinse (TPM), as compared to a ...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.1992.63.1.39
更新日期:1992-01-01 00:00:00
abstract::One hundred and two extracted permanent molars were debrided in 3% H2O2, sealed at the apex, and placed in a vacuum chamber. Safranin dye was introduced into the teeth that were placed in a vacuum of 525 mm of Hg. Observations were made of the external root surface to determine any staining due to patent accessory can...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1978.49.1.21
更新日期:1978-01-01 00:00:00
abstract:BACKGROUND:The Nd:YAG laser has recently been used in the treatment of periodontal disease. However, although a clinical reduction of probing depth and gingival inflammation to this new approach has been reported, it has not been fully evaluated. Interleukin-1 beta (IL- 1beta), a potent stimulator of bone resorption, h...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.1999.70.11.1276
更新日期:1999-11-01 00:00:00
abstract:BACKGROUND:A relationship between periodontitis and chronic respiratory disease has been suggested by recent studies. The aim of this study is to explore the association between periodontitis and chronic obstructive pulmonary disease (COPD) in a Chinese population. METHODS:We conducted a case-control study of 581 COPD...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2012.110472
更新日期:2012-10-01 00:00:00
abstract:BACKGROUND:T cell cytokine profiles in the spleens and anti-Porphyromonas gingivalis antibodies in the sera of P. gingivalis-immunized BALB/c (H-2d), CBA/CaH (H-2k), C57BL6 (H-2b), and DBA/2J (H-2d, C5 deficient) mice were examined. METHODS:Mice were immunized either by intraperitoneal injections of P. gingivalis oute...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2000.71.7.1130
更新日期:2000-07-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to evaluate the effect of smoking on the periodontal status and the salivary composition in subjects with established periodontitis before and after periodontal therapy. METHODS:Our study group included 26 healthy subjects, 12 smokers and 14 non-smokers with established periodo...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1999.70.10.1240
更新日期:1999-10-01 00:00:00
abstract::Ten mouse monoclonal antibodies were prepared against cultured bovine periodontal ligament cells to be used as reagents for the study of periodontal disease and wound healing. Using standard immunohistochemical methods, these antibodies were found to recognize cell surface antigens in formalin-fixed bovine periodontiu...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1991.62.3.190
更新日期:1991-03-01 00:00:00
abstract:BACKGROUND:The objective of this study was to systematically review the diagnostic criteria, indications, and need for treatment of ankyloglossia (tongue-tie), as well as the various treatment options for patients in different age groups. METHODS:The MEDLINE databases and the Cochrane Library were searched according t...
journal_title:Journal of periodontology
pub_type: 杂志文章,评审
doi:10.1902/jop.2009.090086
更新日期:2009-08-01 00:00:00
abstract::The secretion of prostaglandin E2 (PGE2), tumor necrosis factor alpha (TNF alpha), interleukin 1 beta (IL-1 beta), and interleukin 6 (IL-6) by adherent mononuclear cells (AMNC) from 28 patients with early-onset periodontitis was studied. The early onset-periodontitis patients consisted of 12 patients with localized ju...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1994.65.2.139
更新日期:1994-02-01 00:00:00
abstract::The purpose of this study was to quantify glycosaminoglycans (GAG) released into the gingival crevicular fluid (GCF) during health, gingivitis, and adult periodontitis. The investigation tested the hypothesis that increased amounts of GAG can be measured in GCF associated with gingivitis and adult periodontitis as com...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1993.64.3.186
更新日期:1993-03-01 00:00:00
abstract::Partial-mouth scores are often used in epidemiologic studies to estimate the prevalence and severity of periodontal disease. Such estimates systematically underestimate the prevalence of disease, but the bias can be in either direction for disease severity. Three large data sets containing full-mouth examinations (mes...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1988.59.11.707
更新日期:1988-11-01 00:00:00
abstract:BACKGROUND:Despite the potential significance of early soft tissue healing to long-term outcomes, this aspect of one-stage dental implants has not been investigated. The purpose of this prospective study was to characterize clinical and microbiologic parameters of early soft tissue healing around dental implants placed...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2007.070122
更新日期:2007-10-01 00:00:00
abstract:BACKGROUND:The purpose of this multicenter randomly controlled clinical trial was to compare two acellular dermal matrix (ADM) materials produced by different processing techniques, freeze-dried (FDADM) and solvent-dehydrated (SDADM) ADM, in their ability to correct Miller Class I and II recession defects. METHODS:Eig...
journal_title:Journal of periodontology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1902/jop.2014.140198
更新日期:2014-12-01 00:00:00
abstract::Periodontitis is an inflammatory disease caused by microbial infection in the subgingival region. Risk factors associated with the development and progression of this disease are numerous, multifactorial, complex, and often not well defined across individuals and population groups. The focus of this paper is to provid...
journal_title:Journal of periodontology
pub_type: 杂志文章,评审
doi:10.1902/jop.1994.65.5s.539
更新日期:1994-05-01 00:00:00
abstract:BACKGROUND:Titanium (Ti) dental implants have been widely used for prosthetic reconstruction of dentition. Unfortunately, peri-implantitis can result in failure of dental implant osseointegration. Lipopolysaccharide (LPS) acts as a chronic inflammatory stimulus and maintains peri-implant inflammation, worsening the pro...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2014.140386
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND:The aim of this study was to evaluate the efficacy of deproteinized bovine bone mineral with 10% collagen (DBBM-C) soaked with hyaluronic acid (HA) for ridge preservation in compromised extraction sockets. METHODS:Bilateral third, fourth premolars and first molar were hemisected, distal roots were extracted...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1002/JPER.20-0832
更新日期:2021-01-23 00:00:00
abstract:BACKGROUND:Prostaglandin E(2) (PGE(2)), which exerts its biologic actions via EP receptors (EP(1), EP(2), EP(3,) and EP(4)), is a bioactive metabolite of arachidonic acid that is produced by cyclooxygenase (COX)-1 and/or COX-2. In the present study, we investigated whether a mouse cementoblast cell line, OCCM-30 cells,...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2007.060257
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:The development of chronic periodontitis (CP) is a multifactorial process and variation in severity cannot be explained by just a few risk factors. The aims of this study were: 1) to explore the lifestyle and psychosocial factors of CP patients and 2) to estimate the proportion of total CP cases attributable...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2003.74.8.1169
更新日期:2003-08-01 00:00:00
abstract:BACKGROUND:Recently, a genetic marker (IL-1 genotype) that identifies individuals at higher risk for developing severe periodontal disease was discovered. A subgroup of the population reported on earlier was evaluated to determine if knowledge of the patient's IL-1 genotype would improve accuracy in assignment of progn...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1999.70.1.49
更新日期:1999-01-01 00:00:00
abstract::Cyclosporine A (CSA) is a widely used immunosuppressant for transplant patients and is also used for the treatment of a wide variety of systemic diseases with immunologic components. A prominent side effect of CSA administration is gingival overgrowth (hyperplasia). It has been postulated that CSA alters fibroblast ac...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1996.67.3.271
更新日期:1996-03-01 00:00:00
abstract:BACKGROUND:Multiple factors that influence the precision of periodontal probing measurements have been identified. These factors can be categorized as being dependent upon host-related, probe-related, or examiner-related variables. However, the potential influence of examiner handedness (right or left) on the measureme...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2006.050185
更新日期:2006-07-01 00:00:00
abstract:BACKGROUND:Many studies have shown that periodontal disease can be successfully treated. However, there is limited documentation as to what happens when periodontal disease is left untreated. This study examined patients in a private practice who were diagnosed with periodontal disease and did not complete any treatmen...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2003.74.5.672
更新日期:2003-05-01 00:00:00
abstract::The purpose of this study was to evaluate the healing potential of deep, primarily 3wall intrabony defects which were treated by flap debridement and expanded polytetrafluoroethylene (ePTFE) membranes and followed for extended time periods. All of the treated defects were in the mandibular arch. Thirty-two patients we...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1993.64.11s.1138
更新日期:1993-11-01 00:00:00
abstract::An increasing body of evidence supports the concept that host-produced PGE2 mediates much of the tissue destruction that occurs in periodontal disease. PGE2 levels within the crevicular fluid can serve as a static assessment of ongoing disease activity; i.e., rate of attachment loss and bone resorption. New insights i...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1993.64.5s.432
更新日期:1993-05-01 00:00:00
abstract:BACKGROUND:Platelet-rich fibrin (PRF) has recently been applied in osseous regeneration. The aim of the present study is to explore the efficacy of PRF in treatment of intrabony defects (IBDs) in aggressive periodontitis. METHODS:Fifty-four IBDs in 17 patients were treated either with autologous PRF with open flap deb...
journal_title:Journal of periodontology
pub_type: 杂志文章,随机对照试验
doi:10.1902/jop.2017.120661
更新日期:2017-11-01 00:00:00
abstract::This study tested the hypothesis that severe periodontitis in persons with non-insulin-dependent diabetes mellitus (NIDDM) increases the risk of poor glycemic control. Data from the longitudinal study of residents of the Gila River Indian Community were analyzed for dentate subjects aged 18 to 67, comprising all those...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1996.67.10s.1085
更新日期:1996-10-01 00:00:00
abstract::An increased incidence of antibiotic-resistant bacteria and yeast overgrowth has been reported following various periodontal treatments. The objective of this study was to detect possible overgrowth of opportunistic bacteria and fungi as well as changes in normal microbiota after application of a biodegradable deliver...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.1995.66.10.870
更新日期:1995-10-01 00:00:00
abstract:BACKGROUND:Our purpose was to compare the risk of tooth loss caused by periodontal disease between diabetic and nondiabetic individuals and to estimate the relative risk of tooth loss according to the severity and control of diabetes. METHODS:We selected 10,215 individuals who were diagnosed as diabetics in the Korean...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1002/JPER.18-0480
更新日期:2019-06-01 00:00:00