Treatment of Mandibular 3-Wall Intrabony Defects by Flap Debridement and Expanded Polytetrafluoroethylene Barrier Membranes. Long-Term Evaluation of 32 Treated Patients.

Abstract:

:The purpose of this study was to evaluate the healing potential of deep, primarily 3wall intrabony defects which were treated by flap debridement and expanded polytetrafluoroethylene (ePTFE) membranes and followed for extended time periods. All of the treated defects were in the mandibular arch. Thirty-two patients were treated and reexamined at an average of 3 years 5 months. Twenty-four of these patients had re-entry procedures at the second examination. Sixteen of these patients were examined a third time at an average of 4 years 3 months. The patients were evaluated for changes in probing depth (PD), clinical attachment level (CAL), recession, changes in crestal resorption, and defect bone fill. The paired t-test for related samples was used to test for differences between examinations. Between Exams 1 and 2 there was a statistically significant reduction of pocket depth (3.8 mm), gain in clinical attachment level (4.2 mm), and an increase in recession (-1.2 mm). For the 24 patients who had re-entry procedures there was an average defect fill of 4.3 mm (P < 0.0001) and 0.33 mm of crestal resorption (P < 0.0001). The 16 patients who were examined 3 times sustained decreases in PD, gains in CAL, and recession recorded at the second examination. These changes were statistically significant at Exam 3. The results of this study demonstrate that deep, 3-wall intrabony defects treated by debridement and ePTFE barrier membranes will have significant decreases in PD, gains in CAL, recession, decreases in crestal resorption, and gains in bone fill. These gains can be maintained over extended time intervals and are considered to be predictable. J Periodontol 1993; 64:1138-1144.

journal_name

J Periodontol

authors

Becker W,Becker BE

doi

10.1902/jop.1993.64.11s.1138

subject

Has Abstract

pub_date

1993-11-01 00:00:00

pages

1138-1144

eissn

0022-3492

issn

1943-3670

journal_volume

64 Suppl 11S

pub_type

杂志文章
  • Diabetes-associated periodontitis molecular features in infrared spectra of gingival crevicular fluid.

    abstract:BACKGROUND:It has been established previously that infrared spectroscopy (IRS) can be used to identify periodontitis-specific molecular signatures in gingival crevicular fluid (GCF) and to confirm clinical diagnoses. This follow-up study is designed to assess whether this novel technique is also able to differentiate d...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2013.120665

    authors: Xiang X,Duarte PM,Lima JA,Santos VR,Gonçalves TD,Miranda TS,Liu KZ

    更新日期:2013-12-01 00:00:00

  • New composite endpoints to assess efficacy in periodontal therapy clinical trials.

    abstract:BACKGROUND:Clinical attachment level (CAL) and bone height (radiographic or clinical) are two well-accepted endpoint measures for periodontal clinical trials; however, neither one has been shown to be more predictive of long-term success than the other. We propose using a composite endpoint analysis combining clinical ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2006.050275

    authors: Lynch SE,Lavin PT,Genco RJ,Beasley WG,Wisner-Lynch LA

    更新日期:2006-08-01 00:00:00

  • Zirconium dioxide implant abutments for posterior single-tooth replacement: first results.

    abstract:BACKGROUND:Prefabricated implant abutments made of zirconium dioxide (yttria-stabilized polycrystalline tetragonal zirconia; Y-TZP) have proved to be useful in the esthetically demanding anterior region and may also be useful for premolar and molar replacement because of their obvious positive impact on the health of p...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2009.090274

    authors: Nothdurft FP,Pospiech PR

    更新日期:2009-12-01 00:00:00

  • A retrospective cohort study on peri-implant complications in implants up to 10 years of functional loading in periodontally compromised patients.

    abstract:BACKGROUND:Prevalence of peri-implantitis is directly proportional to the time of functional loading. The aim of this retrospective study was to assess the survival and success rates as well as the incidence of peri-implantitis among patients with a history of periodontitis and among implants with 1 to 10 years of func...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1002/JPER.18-0715

    authors: Pandolfi A,Rinaldo F,Pasqualotto D,Sorrentino F,La Torre G,Guerra F

    更新日期:2019-12-20 00:00:00

  • Altered cell motility and attachment with titanium surface modifications.

    abstract:BACKGROUND:Titanium implants are widely used in dentistry to replace lost teeth. Various surface modifications have been used to improve implant retention and osseointegration. This study is designed to compare the ability of three titanium surfaces to promote cell attachment and cell motility of cells relevant to peri...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2011.100733

    authors: Palaiologou A,Stoute D,Fan Y,Lallier TE

    更新日期:2012-01-01 00:00:00

  • Utilization of Dental Services as a Risk Factor for Periodontitis.

    abstract::The relation between utilization of dental services from community dentists and the extent and severity of alveolar bone loss is reported for a panel of men followed for over 6 years. Oral health data were collected by the Department of Veterans Affairs, Dental Longitudinal Study, which began in 1969 and still continu...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1994.65.5s.551

    authors: Brown LJ,Garcia R

    更新日期:1994-05-01 00:00:00

  • The effects of a calorie-reduced diet on periodontal inflammation and disease in a non-human primate model.

    abstract:BACKGROUND:Low-calorie diets are commonplace for reducing body weight. However, no information is available on the effects of a reduced-calorie diet on periodontal inflammation and disease. The purpose of this study was to evaluate the clinical effects of a long-term calorie-restriction (CR) diet on periodontitis in an...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2008.070629

    authors: Branch-Mays GL,Dawson DR,Gunsolley JC,Reynolds MA,Ebersole JL,Novak KF,Mattison JA,Ingram DK,Novak MJ

    更新日期:2008-07-01 00:00:00

  • Aspartate aminotransferase (AST) levels in human periodontium-derived cells.

    abstract::The ability to objectively assess periodontal disease activity can significantly affect periodontal therapy. Aspartate aminotransferase (AST) is released extracellularly upon tissue destruction which suggests its potential as a key index in a quantitative assay for evaluating periodontal disease activity. The purpose ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1996.67.8.733

    authors: Mizuho F,Mori H,Deguchi S,Ogawa Y,Hori T

    更新日期:1996-08-01 00:00:00

  • Commentary: A Translational Medicine Approach to Tooth Transplantation.

    abstract::The autogenous tooth transplantation approach to replace missing teeth has been in use for a long time. Different surgical techniques have been developed to improve prognosis and longevity of transplanted teeth with complete root formation. Many factors reportedly affected short- and long-term success of the procedure...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2017.160820

    authors: Prato GP,Zuccati G,Clauser C

    更新日期:2017-06-01 00:00:00

  • Effect of Periodontal Therapy With Amoxicillin-Metronidazole on Pharyngeal Carriage of Penicillin- and Erythromycin-Resistant Viridans Streptococci.

    abstract:BACKGROUND:Previous studies have focused on antibiotic resistance of Gram-negative bacteria before and after periodontal therapy. The purpose of this analysis is to assess changes in resistance patterns of the commensal Gram-positive microbiota. The viridans group streptococci (VGS) have been suggested to serve as rese...

    journal_title:Journal of periodontology

    pub_type: 杂志文章,随机对照试验

    doi:10.1902/jop.2015.150494

    authors: Mombelli A,Cionca N,Almaghlouth A,Cherkaoui A,Schrenzel J,Giannopoulou C

    更新日期:2016-05-01 00:00:00

  • Histopathological morphometric evaluation of 2 different hydroxyapatite-bone derivatives in sinus augmentation procedures: a comparative study in humans.

    abstract:BACKGROUND:Xenografts to augment the maxillary sinus have been used extensively. The aim of the present study was to evaluate, qualitatively and quantitatively, two different HA derivatives of natural and synthetic sources on newly formed bone in the augmented sinus. METHODS:A bilateral sinus augmentation procedure wi...

    journal_title:Journal of periodontology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1902/jop.2001.72.7.911

    authors: Artzi Z,Nemcovsky CE,Tal H,Dayan D

    更新日期:2001-07-01 00:00:00

  • Axonal transport of fluorescent carbocyanine dyes allows mapping of peripheral nerve territories in gingiva.

    abstract::Sensory innervation of gingival tissue can cause neurogenic inflammation that depends on the extent of the branching area of the peripheral nerve fibers. We designed the present study to determine whether single trigeminal axons branch to both the buccal and palatal gingiva of maxillary molars of adult rats. Accumulat...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1995.66.9.817

    authors: Sugaya A,Chudler EH,Byers MR

    更新日期:1995-09-01 00:00:00

  • Biodegradation of three different collagen membranes in the rat calvarium: a comparative study.

    abstract:BACKGROUND:Collagen barrier membranes are commonly applied in periodontal and bone-regenerative procedures. Membranes differ in their resorption pattern following implantation, thus influencing clinical outcome. The purpose of this study was to quantitatively evaluate the biodegradation of three different commercially ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2008.070361

    authors: Moses O,Vitrial D,Aboodi G,Sculean A,Tal H,Kozlovsky A,Artzi Z,Weinreb M,Nemcovsky CE

    更新日期:2008-05-01 00:00:00

  • Acute necrotizing ulcerative gingivitis. A transmission electron microscope study.

    abstract::The purpose of this study was to provide additional evidence that in the lesions of acute necrotizing ulcerative gingivitis (ANUG), spirochetes and other microorganisms are capable of invading the nonnecrotic lamina propria of affected gingivae. Biopsies from eight patients with pathognomonic signs of ANUG were obtain...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1983.54.11.671

    authors: Courtois GJ 3rd,Cobb CM,Killoy WJ

    更新日期:1983-11-01 00:00:00

  • Quantitative assessment of free gingival grafts with and without periosteum and osseous perforation.

    abstract::Forty free gingival grafts were performed on 5 adult Rhesus monkeys as follows: 10 grafts were placed on recipient sites with periosteum; 10 grafts on periosteum and perforated cortical plate; 10 grafts on bared bone; and 10 grafts on perforated bared bone. All free autografts (7 X 5 X 1 mm) were taken from the palata...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1978.49.1.15

    authors: Bissada NF,Sears SB

    更新日期:1978-01-01 00:00:00

  • Redefining the biologic width in severe, generalized, chronic periodontitis: implications for therapy.

    abstract:BACKGROUND:Previous studies demonstrated significant variability in the histologic biologic width in periodontal health and mild periodontitis. The purpose of this study was to determine whether the previously established dimensions of the biologic width applied to subjects with severe, generalized, chronic periodontit...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2008.080066

    authors: Novak MJ,Albather HM,Close JM

    更新日期:2008-10-01 00:00:00

  • Root coverage using the coronally positioned flap with or without a subepithelial connective tissue graft.

    abstract:BACKGROUND:Various surgical techniques have been proposed for treating gingival recession. This randomized clinical trial compared the coronally positioned flap (CPF) alone or in conjunction with a subepithelial connective tissue graft (SCTG) in the treatment of gingival recession. METHODS:Eleven non-smoking subjects ...

    journal_title:Journal of periodontology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1902/jop.2004.75.3.413

    authors: da Silva RC,Joly JC,de Lima AF,Tatakis DN

    更新日期:2004-03-01 00:00:00

  • Local antibody responses in periodontal diseases.

    abstract::The relationship between local and systemic host antibody responses, colonization of subgingival plaque by periodontal disease-associated microorganisms and the progression of periodontal disease was assessed in 61 patients. Serum antibody levels to a battery of oral microorganisms were determined by an enzyme-linked ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1985.56.11s.51

    authors: Ebersole JL,Taubman MA,Smith DJ

    更新日期:1985-11-01 00:00:00

  • Periodontal status and neutrophilic enzyme levels in gingival crevicular fluid during pregnancy and postpartum.

    abstract:BACKGROUND:Pregnancy induces or enhances susceptibility to gingivitis; however, the presence and role of neutrophilic enzymes in pregnancy-related gingivitis are not well known. The present study demonstrates the relationship between neutrophilic enzymes in gingival crevicular fluid (GCF) and periodontal status during ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2010.100147

    authors: Gürsoy M,Könönen E,Gürsoy UK,Tervahartiala T,Pajukanta R,Sorsa T

    更新日期:2010-12-01 00:00:00

  • Effect of selected beta-blockers on supragingival calculus formation.

    abstract::Supragingival plaque and calculus indices, salivary flow rates, pH, ionic and total calcium concentrations, total phosphate concentration, and the number of cervical restorations and caries lesions were measured in 29 subjects using systemic beta-(beta) blockers and in 28 subjects who were not taking any systemic medi...

    journal_title:Journal of periodontology

    pub_type: 临床试验,杂志文章

    doi:10.1902/jop.1996.67.4.428

    authors: Breuer MM,Mboya SA,Moroi H,Turesky SS

    更新日期:1996-04-01 00:00:00

  • Demineralization of the contacting surfaces in autologous onlay bone grafts improves bone formation and bone consolidation.

    abstract:BACKGROUND:Autologous bone grafts are usually well consolidated after 4 to 5 months but can be incompletely interlocked with the native bone. This study investigated the effect of acid demineralization of the graft-bed interface on graft consolidation. METHODS:Onlay bone grafts were performed on the calvaria of 36 gui...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2013.130298

    authors: Rezende ML,Consolaro A,Sant'Ana AC,Damante CA,Greghi SL,Passanezi E

    更新日期:2014-05-01 00:00:00

  • A hyperactive neutrophil phenotype in patients with refractory periodontitis.

    abstract:BACKGROUND:Neutrophils (PMNs) are critical components of the innate immune system and help to maintain oral health in the face of a constant bacterial challenge. However, along with protecting the periodontium from microbial invasion, these cells release potent lysosomal enzymes and oxygen radicals that can be destruct...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2007.070107

    authors: Johnstone AM,Koh A,Goldberg MB,Glogauer M

    更新日期:2007-09-01 00:00:00

  • Exposure to occupational noise and periodontitis in Korean workers.

    abstract:BACKGROUND:Chronic exposure to occupational noise is reported to cause a wide range of health problems. But, there are no reports on studies investigating the association between noise exposure and periodontitis. The purpose of this study was to examine the relationship between occupational noise exposure and periodont...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1002/JPER.17-0484

    authors: Shim SH,Han DH

    更新日期:2018-04-01 00:00:00

  • The healing of gingival wounds in miniature swine.

    abstract::Standard wounds of simple incision and partial excision of the dentogingival junction were made in miniature swine. The healing from the 1st to the 14th day were described clinically and histologically, and the standardization of the wounds permitted quantitative and statistical analysis. In wounds that are closely ad...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1980.51.6.318

    authors: Wirthlin MR,Yeager JE,Hancock EB,Gaugler RW

    更新日期:1980-06-01 00:00:00

  • Monoclonal antibodies to periodontal ligament cells.

    abstract::Ten mouse monoclonal antibodies were prepared against cultured bovine periodontal ligament cells to be used as reagents for the study of periodontal disease and wound healing. Using standard immunohistochemical methods, these antibodies were found to recognize cell surface antigens in formalin-fixed bovine periodontiu...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1991.62.3.190

    authors: DuBois WT,Edmondson J,Milam SB,Winborn WB,Hay R,Carnes DL,Kornman KS,Klebe RJ

    更新日期:1991-03-01 00:00:00

  • Healing responses to grafting of combined collagen-decalcified bone in periodontal defects in dogs.

    abstract::The feasibility of a new combined collagen gel-autolysed antigen-extracted allogeneic bone implant was tested. Its effect on gaining new attachment in surgically created defects in four dogs was evaluated over 24 weeks. As controls, sites receiving implants of the bone implant alone, nonimplanted and untreated defects...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1986.57.2.84

    authors: Blumenthal N,Sabe T,Barrington E

    更新日期:1986-02-01 00:00:00

  • Histological evaluation of effects produced in alveolar bone following gingival incision with an electrosurgical scalpel.

    abstract::Gingival incisions were performed distal to each of the two lower incisors on 25 adult male guinea pigs. For every animal, electrosection with an electrosurgical scalpel was used on one side, and a conventional scalpel was used on the other. The surgical instruments in all cases were brought into direct contact with p...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1975.46.1.40

    authors: Nixon KC,Adkins KF,Keys DW

    更新日期:1975-01-01 00:00:00

  • Application of periodontal tissue engineering using enamel matrix derivative and a human fibroblast-derived dermal substitute to stimulate periodontal wound healing in Class III furcation defects.

    abstract:BACKGROUND:Enamel matrix derivative (EMD) has been shown to promote several aspects of periodontal regeneration in vitro and in vivo. Recently, a bioengineered tissue (DG) was developed to promote wound healing of chronic skin ulcers. This pilot study sought to assess the effects of EMD and DG, alone or in combination,...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2006.030264

    authors: Hovey LR,Jones AA,McGuire M,Mellonig JT,Schoolfield J,Cochran DL

    更新日期:2006-05-01 00:00:00

  • Treatment of localized gingival recessions using gingival unit grafts: a randomized controlled clinical trial.

    abstract:BACKGROUND:One of the success factors in periodontal plastic surgery is the synergistic relationship between involved tissues and vascular supply. Gingiva as a functional unit is unique with a specific vascular configuration and contains the supracrestal portion naturally created to survive over avascular root surfaces...

    journal_title:Journal of periodontology

    pub_type: 杂志文章,随机对照试验

    doi:10.1902/jop.2012.110685

    authors: Kuru B,Yıldırım S

    更新日期:2013-01-01 00:00:00

  • Gingival transcriptome patterns during induction and resolution of experimental gingivitis in humans.

    abstract:BACKGROUND:To our knowledge, changes in the patterns of whole-transcriptome gene expression that occur during the induction and resolution of experimental gingivitis in humans were not previously explored using bioinformatic tools. METHODS:Gingival biopsy samples collected from 14 subjects during a 28-day stent-induce...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2009.080645

    authors: Offenbacher S,Barros SP,Paquette DW,Winston JL,Biesbrock AR,Thomason RG,Gibb RD,Fulmer AW,Tiesman JP,Juhlin KD,Wang SL,Reichling TD,Chen KS,Ho B

    更新日期:2009-12-01 00:00:00