Abstract:
:This study tested the hypothesis that severe periodontitis in persons with non-insulin-dependent diabetes mellitus (NIDDM) increases the risk of poor glycemic control. Data from the longitudinal study of residents of the Gila River Indian Community were analyzed for dentate subjects aged 18 to 67, comprising all those: 1) diagnosed at baseline with NIDDM (at least 200 mg/dL plasma glucose after a 2-hour oral glucose tolerance test); 2) with baseline glycosylated hemoglobin (HbA1 ) less than 9%; and 3) who remained dentate during the 2-year follow-up period. Medical and dental examinations were conducted at 2-year intervals. Severe periodontitis was specified two ways for separate analyses: 1) as baseline periodontal attachment loss of 6 mm or more on at least one index tooth; and 2) baseline radiographic bone loss of 50% or more on at least one tooth. Clinical data for loss of periodontal attachment were available for 80 subjects who had at least one follow-up examination, 9 of whom had two follow-up examinations at 2-year intervals after baseline. Radiographic bone loss data were available for 88 subjects who had at least one follow-up examination, 17 of whom had two follow-up examinations. Poor glycemic control was specified as the presence of HbA1 of 9% or more at follow-up. To increase the sample size, observations from baseline to second examination and from second to third examinations were combined. To control for non-independence of observations, generalized estimating equations (GEE) were used for regression modeling. Severe periodontitis at baseline was associated with increased risk of poor glycemic control at follow-up. Other statistically significant covariates in the GEE models were: 1) baseline age; 2) level of glycemic control at baseline; 3) having more severe NIDDM at baseline; 4) duration of NIDDM; and 5) smoking at baseline. These results support considering severe periodontitis as a risk factor for poor glycemic control and suggest that physicians treating patients with NIDDM should be alert to the signs of severe periodontitis in managing NIDDM. J Periodontol 1996;67:1085-1093.
journal_name
J Periodontoljournal_title
Journal of periodontologyauthors
Taylor GW,Burt BA,Becker MP,Genco RJ,Shlossman M,Knowler WC,Pettitt DJdoi
10.1902/jop.1996.67.10s.1085subject
Has Abstractpub_date
1996-10-01 00:00:00pages
1085-1093eissn
0022-3492issn
1943-3670journal_volume
67 Suppl 10Spub_type
杂志文章abstract::Fresh and frozen allogeneic iliac grafts were used in surgically prepared intraosseous defects. Four adult rhesus monkeys provided 19 specimens from 0 to 56 days postoperative. There were 8 specimens for each type of graft and 3 others used as controls. Histologic sections from each specimen were prepared and a descri...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1976.47.4.187
更新日期:1976-04-01 00:00:00
abstract::An intraindividual double-blind crossover study was designed in order to see if a 1% chlorhexidine gel used twice a day could substitute for ordinary toothpaste in group of maintenance-care patients with poor oral hygiene. Twenty patients from a student clinic participated, each with a long history of maintenance-care...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章
doi:10.1902/jop.1986.57.6.364
更新日期:1986-06-01 00:00:00
abstract:BACKGROUND:Bacterial constituents, such as Gram-negative derived lipopolysaccharide (LPS), can initiate inflammatory bone loss through induction of host-derived inflammatory cytokines. The aim of this study was to establish a model of aggressive inflammatory alveolar bone loss in rats using LPS derived from the periodo...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2007.060321
更新日期:2007-03-01 00:00:00
abstract::Three block sections of treated human intraosseous lesions within one individual are presented. These lesions were debrided, filled with autogenous grafts and at two sites the root was treated with citric acid. The treated sites were lightly root planed once a month and the blocks were removed 6 months after surgery. ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1983.54.2.67
更新日期:1983-02-01 00:00:00
abstract::Ultrasonic scalers may be operated at different power settings which may influence the final therapeutic result. The displacement amplitude of the scaling tip may affect scaling efficiency or the degree of root surface damage. This investigation aimed to determine whether there was any difference in periodontal healin...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.1995.66.9.756
更新日期:1995-09-01 00:00:00
abstract:BACKGROUND:Previous studies suggest that periodontitis is closely related to obesity and metabolic syndrome. Leptin, a pleiotrophic hormone produced by adipose tissue, has been reported to be related to periodontitis. This study investigates the effects of periodontal treatment on the serum levels of leptin and other c...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2010.090741
更新日期:2010-08-01 00:00:00
abstract:BACKGROUND:Alveolar bone regeneration is frequently necessary prior to placement of implants. Efforts to improve wound healing have focused on factors that may enhance bone formation following guided bone regeneration (GBR) techniques alone or in combination with bone replacement graft materials. Recent reports suggest...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2000.71.10.1654
更新日期:2000-10-01 00:00:00
abstract:BACKGROUND:This cross-sectional study was planned to investigate whether patients with chronic periodontitis exhibit different salivary or plasma concentrations of Toll-like receptor (TLR) 2 and TLR4 compared to subjects who are clinically healthy. METHODS:Whole saliva and plasma samples were obtained and full-mouth c...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2010.100467
更新日期:2011-06-01 00:00:00
abstract:BACKGROUND:Little information is available about the effects of the cessation of cigarette smoking on oral health, although cigarette smoking has been shown to be associated with a variety of oral diseases. The aim of this study was to compare periodontal status, salivary proteolytic activity, especially collagenase-2 ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1999.70.11.1361
更新日期:1999-11-01 00:00:00
abstract:BACKGROUND:There is limited information regarding marginal bone-level changes around immediately loaded implants placed with the osteotome technique. The aim of this case series is to prospectively evaluate the clinical and radiographic outcome of immediately loaded implants placed with the osteotome technique over a 1...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章
doi:10.1902/jop.2011.100751
更新日期:2011-11-01 00:00:00
abstract::Enormous advances have been made over the past decade concerning the proper use of statistical techniques in reporting periodontal research. However, numerous articles still appear which use inappropriate or less than optimal statistical methods. This paper describes the most common problems encountered in a recent re...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1990.61.4.206
更新日期:1990-04-01 00:00:00
abstract::Twelve gingival samples removed from 6 human volunteers were sectioned in small pieces, parts of which served as uncultured pieces. The remaining pieces were organ cultured for 5 hours in control, compound 48/80, and antihuman IgE media. Uncultured tissues, cultured tissues, and cultured spent media were analyzed spec...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1975.46.3.171
更新日期:1975-03-01 00:00:00
abstract:BACKGROUND:This study aims to identify predictors of performed oral hygiene behaviors (OHBs) based on the Theory of Planned Behavior (TPB), oral health knowledge, and demographic factors. METHODS:Using a questionnaire, 381 participants in three general dental offices and one hospital dental department in York, Pennsyl...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2015.150239
更新日期:2016-03-01 00:00:00
abstract:BACKGROUND:Recent research suggests that osteopenia may be a predisposing factor for periodontal tissue destruction. If so, then a relationship should exist between measures of systemic bone mineral density and periodontal tissue destruction. The purpose of the present cross-sectional study was to evaluate the associat...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.1999.70.9.982
更新日期:1999-09-01 00:00:00
abstract:BACKGROUND:Platelet-rich plasma (PRP) has been promoted as a surgical adjunct to enhance hard and soft tissue wound healing. Although anecdotally reported to be of value, the results of controlled studies examining the added effects of PRP on surgical procedures have been mixed. The purpose of this study was to test th...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2009.080626
更新日期:2009-06-01 00:00:00
abstract:BACKGROUND:Previous studies have demonstrated that bone demineralization can improve consolidation in bone grafts. The biologic mechanisms underlying this phenomenon remain unclear. METHODS:Twelve adult male guinea pigs were used in this experiment. Forty-five bone samples removed from the calvaria of nine animals wer...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2014.130657
更新日期:2015-01-01 00:00:00
abstract::THIS INVESTIGATION was undertaken to determine the distribution pattern and readability level of 20 widely distributed printed items containing periodontal health education literature. Average annual distribution was obtained from distributors of the material. The Minnesota Interactive Readability Approximation Progra...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1983.54.9.538
更新日期:1983-09-01 00:00:00
abstract:BACKGROUND:Regenerative periodontal treatment aims to restore the attachment of the periodontal ligament and gingival collagen fibers to both the cementum of the root surface and alveolar bone. Fibroblasts are the predominant cells of the periodontal ligament and gingiva and have important roles in the function and reg...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2003.74.4.458
更新日期:2003-04-01 00:00:00
abstract:BACKGROUND:This meta-analysis was conducted to examine the relationship between periodontal diseases and coronary heart diseases (CHD) and cerebrovascular diseases (CVD) in observational studies. METHODS:This study was based on seven cohort studies and four studies of other designs that met prestated inclusion criteri...
journal_title:Journal of periodontology
pub_type: 杂志文章,meta分析,评审
doi:10.1902/jop.2004.75.8.1046
更新日期:2004-08-01 00:00:00
abstract::Several different types of interactions are possible between a chemical, a mixture of chemicals, and associated extrinsic factors (i.e., mechanical irritation) in the oral mucosa. These interactions can be broadly classified as irritative or allergenic in nature. In each case, the pathology usually includes mucosal in...
journal_title:Journal of periodontology
pub_type: 杂志文章,评审
doi:10.1902/jop.1998.69.6.620
更新日期:1998-06-01 00:00:00
abstract:BACKGROUND:Several studies have indicated a relationship between rheumatoid arthritis and periodontal disease. The aim of this study was to investigate the association between the circulating proinflammatory mediators tumor necrosis factor-alpha (TNF-alpha), interleukin-1beta, prostaglandin E(2), serotonin, rheumatoid ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2008.070599
更新日期:2008-09-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to evaluate inter-implant bone crest height changes between immediate and non-immediate dental implants placed in the anterior maxillary region. METHODS:A retrospective study was conducted on consecutively treated patients requiring at least two adjacent implants in the anterio...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2007.060443
更新日期:2007-06-01 00:00:00
abstract::Bacterial invasion of the pocket epithelium and underlying connective tissue was found in seven cases of advanced human periodontitis. Four cases showed invasion of the epithelium as well as the connective tissue while in the other three cases bacterial invasion was limited to the pocket epithelium. The microorganisms...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1984.55.10.567
更新日期:1984-10-01 00:00:00
abstract:BACKGROUND:This commentary compares the abilities of full-mouth disinfection (FDIS), full-mouth root planing (FRP), and partial-mouth disinfection (PDIS) to improve periodontal health. FDIS consists of 4 quadrants of root planing completed within 24 hours with adjunctive chlorhexidine therapies (e.g., rinsing, subgingi...
journal_title:Journal of periodontology
pub_type: 杂志文章,评审
doi:10.1902/jop.2002.73.7.797
更新日期:2002-07-01 00:00:00
abstract::This paper briefly reviews the historical relationship between oral medicine and periodontics. The reasons for including structured clinical oral medicine in a postdoctoral program in periodontics are discussed. Problems and solutions to such an integrated program are outlined. Guidelines for broadening the base of th...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1986.57.7.426
更新日期:1986-07-01 00:00:00
abstract:BACKGROUND:Previous studies have focused on antibiotic resistance of Gram-negative bacteria before and after periodontal therapy. The purpose of this analysis is to assess changes in resistance patterns of the commensal Gram-positive microbiota. The viridans group streptococci (VGS) have been suggested to serve as rese...
journal_title:Journal of periodontology
pub_type: 杂志文章,随机对照试验
doi:10.1902/jop.2015.150494
更新日期:2016-05-01 00:00:00
abstract::The objective of this study was to evaluate if the biologic membrane utilized for GTR can be impregnated by tetracycline hydrochloride and if the chemotherapeutic agent, once impregnated, can be released in minimal inhibitory concentrations for a period compatible with clinical application. Initially, an in vitro stud...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1995.66.11.978
更新日期:1995-11-01 00:00:00
abstract::Smoker's melanosis is a benign pigmentation of the oral mucosa, predominantly observed on the attached anterior mandibular gingiva and interdental papillae. These macular lesions are independent of genetic factors, therapeutic medication usage, and various systemic disorders. As a group they are often seen after the t...
journal_title:Journal of periodontology
pub_type: 杂志文章,评审
doi:10.1902/jop.1991.62.8.524
更新日期:1991-08-01 00:00:00
abstract::The placement of hydroxyapatite-coated dental implants in fresh extraction sockets was compared to placement in adjacent healed sites in 14 patients. Systematic sequential documentation was obtained regarding periodontal health, radiographic bone levels, and implant stability at the time of implant placement, at uncov...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1991.62.7.468
更新日期:1991-07-01 00:00:00
abstract:BACKGROUND:Peri-implantitis is a complex polymicrobial biofilm-induced inflammatory osteolytic gingival infection that results in orofacial implant failures. To the best knowledge of the authors, there are no preclinical in vivo studies in implant dentistry that have investigated the inflammatory response to known micr...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2016.160273
更新日期:2017-02-01 00:00:00