Abstract:
:Twelve gingival samples removed from 6 human volunteers were sectioned in small pieces, parts of which served as uncultured pieces. The remaining pieces were organ cultured for 5 hours in control, compound 48/80, and antihuman IgE media. Uncultured tissues, cultured tissues, and cultured spent media were analyzed spectrofluorometrically for histamine content. The uncultured tissues contained a mean (plus or minus SE) of 5.41 plus or minus 0.60 mug/g of histamine and were considered to contain 100 percent total histamine. The percentage of the total histamine released into the medium was 8.24 percent for cultured control, 56.7 percent for antihuman IgE, and 66.7 percent for compound 48/80. Significant histamine release into medium was noted for antihuman IgE (P less than 0.0005) and for compound 48/80 (P equals 0.005), but these two were not significantly different from each other (P greater than 0.25). Significant tissue histamine reduction was recorded for tissues cultured in compound 48/80 (P less than 0.025), whereas a significant tissue histamine synthesis was demonstrated for tissues cultured in antihuman IgE (P less than 0.05). The control tissues revealed neither significant histamine release into the medium nor significant tissue histamine reduction or synthesis. The results demonstrate IgE in clinically healthy human gingiva, show its association with gingival mast cell histamine release, and establish an in vitro model system for further human mast cell study. Thus, the concept of an association between IgE antibodies and human gingival mast cells is supported.
journal_name
J Periodontoljournal_title
Journal of periodontologyauthors
Schwartz J,Dibblee Mdoi
10.1902/jop.1975.46.3.171subject
Has Abstractpub_date
1975-03-01 00:00:00pages
171-7issue
3eissn
0022-3492issn
1943-3670journal_volume
46pub_type
杂志文章abstract:BACKGROUND:The efficacy of various partial-mouth recording (PMR) systems is analyzed in the evaluation of periodontal status, using index teeth and different combinations of quadrants. METHODS:The study group was formed of 108 adults aged 25 to 65 years old. A full-mouth examination (FME) was performed in all particip...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2013.130389
更新日期:2014-06-01 00:00:00
abstract:BACKGROUND:A disintegrin and metalloproteinase 28 (ADAM28) is considered to be the possible virulence gene for congenital hypoplasia of tooth root. Periodontal ligament stem cells (PDLSCs) are regarded as playing crucial roles in the developing process of the periodontium and are generally used in dental regenerative m...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2010.090703
更新日期:2010-06-01 00:00:00
abstract::The ability to objectively assess periodontal disease activity can significantly affect periodontal therapy. Aspartate aminotransferase (AST) is released extracellularly upon tissue destruction which suggests its potential as a key index in a quantitative assay for evaluating periodontal disease activity. The purpose ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1996.67.8.733
更新日期:1996-08-01 00:00:00
abstract:BACKGROUND:Periopathogens and cariogenic species survive more than 48 hours on toothbrushes even under dry storage. This study examined a decontamination of toothbrushes by means of the bactericidal effect of different toothpastes or a special coating of the tufts. METHODS:Eight untreated periodontitis patients were p...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2003.74.3.312
更新日期:2003-03-01 00:00:00
abstract::The purpose of this study was to evaluate the effects of the Nd:YAG laser on in vitro fibroblast attachment to endotoxin-treated root surfaces and to describe any laser-induced cementum surface alterations. Thirty 4 mm x 4 mm cementum segments were obtained from unerupted third molars. The treatment groups were as fol...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1992.63.7.626
更新日期:1992-07-01 00:00:00
abstract:BACKGROUND:The possible association between oral infection and chronic inflammation and cardiovascular disease risk has been studied intensively. The present study is designed to determine the strength of association between edentulism and angina pectoris in Mexican adults aged 35 years and older. METHODS:Using the to...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2013.130186
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:Periodontitis has been associated with lacunar infarct (LI), a type of cerebral small vessel disease. The objective of this study was to ascertain whether periodontitis is associated with increased circulating levels of systemic inflammation and endothelial dysfunction biomarkers in patients with LI. METHOD...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1002/JPER.18-0560
更新日期:2019-05-01 00:00:00
abstract::The American Academy of Periodontology has developed the following parameter on the treatment of chronic periodontitis with slight to moderate loss of periodontal supporting tissues. Patients should be informed of the disease process, therapeutic alternatives, potential complications, expected results, and their respo...
journal_title:Journal of periodontology
pub_type: 指南,杂志文章,实务指引
doi:10.1902/jop.2000.71.5-S.853
更新日期:2000-05-01 00:00:00
abstract::Some confusion exists in the literature whether correlations exist between gingivitis severity and plaque levels as measured by the corresponding indices. The results of a clinical trial and a re-analysis of literature data indicate that a strong statistical correlation exists between the Löe-Silness Gingival Index va...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1989.60.4.172
更新日期:1989-04-01 00:00:00
abstract:BACKGROUND:Patients with Kostmann syndrome (severe congenital neutropenia [SCN]) typically normalize their absolute neutrophil count (ANC) upon granulocyte colony-stimulating factor (G-CSF) therapy. However, although they no longer experience life-threatening bacterial infections, they frequently still have recurrent g...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2006.050191
更新日期:2006-04-01 00:00:00
abstract::The report is a review of the literature related to hepatitis B and its implications for dental practitioners. Hepatitis B represents a serious health risk among dentists and simple preventive measures can greatly reduce the risk of transmission or contraction of the disease. Certain positive findings in a healthy his...
journal_title:Journal of periodontology
pub_type: 杂志文章,评审
doi:10.1902/jop.1980.51.3.162
更新日期:1980-03-01 00:00:00
abstract::Proposing to place endosseous implants is an integral facet of dental treatment plans. Their insertion is usually associated with a low incidence of untoward events. However, despite careful planning, surgical complications can arise: infection, intraoral hemorrhage, wound dehiscence, postoperative pain, lack of prima...
journal_title:Journal of periodontology
pub_type: 杂志文章,评审
doi:10.1902/jop.2008.070067
更新日期:2008-08-01 00:00:00
abstract::Localized juvenile periodontitis (LJP) is an aggressive periodontal disease of familial nature. Neutrophils from a majority of patients with this disease exhibit decreased Chemotaxis with increased adherence, oxidative burst, and degranulation in response to opsonized bacteria. It is proposed that the biological basis...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1996.67.3s.337
更新日期:1996-03-01 00:00:00
abstract::The levels of serum antibody reactive to selected periodontopathogens were determined in 182 clinically characterized patients: 35 healthy control, 50 juvenile periodontitis, 42 adult periodontitis and 55 rapidly progressive periodontitis. Reactive antibody levels were determined using an enzyme-linked immunosorbent a...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1985.56.8.464
更新日期:1985-08-01 00:00:00
abstract::This study describes the histologic characteristics of root surfaces of primary teeth from children with prepubertal periodontitis (PP). Fifteen primary teeth from 4 children with PP, and 2 control primary teeth from 2 healthy children were examined. Light microscopy revealed normal root surfaces in the control teeth....
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1998.69.3.337
更新日期:1998-03-01 00:00:00
abstract:BACKGROUND:This study examines whether preceding assessment of periodontal status in patients with established coronary artery disease (CAD) can predict future CAD endpoints (myocardial infarction, new revascularization procedure, or CAD-related death) during 8-year follow-up and whether the changes in periodontal stat...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2013.120730
更新日期:2014-03-01 00:00:00
abstract::The aim of this controlled clinical trial was to assess the effect on healing following tetracycline (TTC) conditioning and fibrin-fibronectin sealing system (FFSS) application in association with flap debridement surgery (FDS) in 11 patients under treatment for moderate to severe periodontitis. Selection criteria inc...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.1996.67.7.688
更新日期:1996-07-01 00:00:00
abstract:BACKGROUND:Little is known about systemic, environmental, and periodontal risk factors of gingival recessions. This study identifies variables related to buccal gingival recessions in an adult French population; this study uses data collected in the First National Periodontal and Systemic Examination Survey. METHODS:T...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2010.100102
更新日期:2010-10-01 00:00:00
abstract:BACKGROUND:Epidermolysis bullosa acquisita (EBA) is an uncommon, acquired, chronic subepidermal bullous disease. This report describes a case of EBA with gingival involvement. A 43-year-old woman with EBA was referred to our clinic for periodontal therapy because of gingival tenderness and bleeding. She has been on cyc...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2001.72.4.550
更新日期:2001-04-01 00:00:00
abstract:BACKGROUND:Epidemiological studies have suggested that there is a genetic component to susceptibility to chronic periodontitis. Studies in humans and in animal models have suggested that some of the important components may be polymorphisms in key immunological genes. METHODS:This paper summarizes previously published...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2005.76.11-S.2042
更新日期:2005-11-01 00:00:00
abstract:BACKGROUND:Considering the role of growth factors in periodontal regeneration, the aim of this study was to evaluate the influence of platelet-derived growth factor (PDGF)-BB, insulin-like growth factor (IGF)-1, and transforming growth factor-beta 1(TGF-β1), alone or in combination, on the rate of proliferation and adh...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2007.070119
更新日期:2007-10-01 00:00:00
abstract:BACKGROUND:To improve regenerative therapies, it is important to understand the cells and factors modulating periodontal tissues. Our group has focused on bone sialoprotein (BSP), a mineralized tissue-selective protein considered to be involved in the initiation of cementogenesis and osteogenesis. In this study, we exa...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2006.050057
更新日期:2006-02-01 00:00:00
abstract:BACKGROUND:The purpose of this case series study was to evaluate posterior single-tooth implant survival and the long-term conditions of the adjacent teeth. METHODS:A retrospective evaluation of 1,162 consecutive patients with a single missing posterior tooth treated with 1,377 external hex implants supporting 1,365 r...
journal_title:Journal of periodontology
pub_type: 杂志文章,多中心研究
doi:10.1902/jop.2008.080188
更新日期:2008-12-01 00:00:00
abstract:BACKGROUND:Evaluation of clinical long-term results 20 years after connective tissue grafting (CTG) or guided tissue regeneration (GTR) using bioabsorbable barriers for root coverage therapy. METHODS:Initially, 15 patients with 38 Miller Class I and II recession defects underwent CTG or GTR according to random assignm...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1002/JPER.19-0203
更新日期:2020-03-01 00:00:00
abstract::Subtraction radiography requires radiographs made with identical projection geometry. Recently a new radiographic aiming device and an x-ray beam manipulator made it possible to repeat radiographic exposures in vivo with small angular errors and to measure the angular errors occurring. The purpose of the present inves...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1993.64.4.278
更新日期:1993-04-01 00:00:00
abstract::Periodontal data typically have a hierarchical structure, with sites grouped within individuals, and individuals grouped within communities. Also, the occasion may be regarded as another level since the acquired knowledge indicates that periodontal disease activity may vary over time. Conventional statistical tests ar...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1992.63.8.690
更新日期:1992-08-01 00:00:00
abstract:BACKGROUND:Peri-implantitis is a complex polymicrobial biofilm-induced inflammatory osteolytic gingival infection that results in orofacial implant failures. To the best knowledge of the authors, there are no preclinical in vivo studies in implant dentistry that have investigated the inflammatory response to known micr...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2016.160273
更新日期:2017-02-01 00:00:00
abstract::THE MAXILLARY anterior region presents a difficult and unique therapeutic challenge to both the periodontist and restorative dentist. Although access for surgical and prosthetic procedures is certainly easiest in this part of the mouth, the problem of esthetics, in terms of increased tooth length and loss of interdent...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1981.52.4.208
更新日期:1981-04-01 00:00:00
abstract::The capacity of epithelial cells to migrate and grow from gingival explants cultured on mineralized and partially demineralized root surfaces in an in vitro system was assessed. Explants of attached gingiva were obtained from mongrel dogs, cut into rectangular pieces (1 x 2 mm) and cultured either on mineralized or pa...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1988.59.8.531
更新日期:1988-08-01 00:00:00
abstract::The prevalence and features of 3 types of exostoses commonly encountered during periodontal surgery were studied in a sample of 328 modern American skulls drawn from the collection at the American Museum of Natural History. Measurements were made of the height, width, and breadth of exostoses. The relationship to teet...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1999.70.3.329
更新日期:1999-03-01 00:00:00