Abstract:
:The capacity of epithelial cells to migrate and grow from gingival explants cultured on mineralized and partially demineralized root surfaces in an in vitro system was assessed. Explants of attached gingiva were obtained from mongrel dogs, cut into rectangular pieces (1 x 2 mm) and cultured either on mineralized or partially demineralized cementum in a defined culture medium containing transferrin, insulin, epidermal growth factor, cortisone, high density lipoprotein and selenium. After seven days of culture, the specimens were prepared for scanning electron microscopic examination. The amount of epithelial outgrowth from each explant was assessed by measuring the distances between the four aspects of the rectangular explant and the furthest epithelial cell located opposite to each of these aspects. The mean value obtained for epithelial outgrowth of explants grown on mineralized cementum was six times higher than that for explants cultured on partially demineralized cementum. These results indicate that partially demineralized cementum does not support epithelial growth and migration in vitro.
journal_name
J Periodontoljournal_title
Journal of periodontologyauthors
Pitaru S,Hekmati M,Soldinger M,Savion Ndoi
10.1902/jop.1988.59.8.531subject
Has Abstractpub_date
1988-08-01 00:00:00pages
531-4issue
8eissn
0022-3492issn
1943-3670journal_volume
59pub_type
杂志文章abstract:BACKGROUND:Surface modifications to dental implants have been used in an attempt to accelerate the osseointegration process. The objective of this study was to biomechanically/histomorphometrically evaluate a bioceramic grit-blasted and acid-etched surface (BGB/AA; test) versus a dual acid-etched implant surface (contr...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2008.080106
更新日期:2008-10-01 00:00:00
abstract:BACKGROUND:It has been shown that lowering the concentration of chlorhexidine (CHX) in mouthrinses from 0.2% to 0.12% does not adversely affect inhibition of plaque accumulation. The aim of this study was to evaluate the inhibition of plaque growth by 2 commercially available mouthrinses used according to the manufactu...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.2003.74.2.214
更新日期:2003-02-01 00:00:00
abstract::This report describes a case of rapidly progressive periodontal tissue breakdown and bone loss in an HIV-infected markedly immunosuppressed homosexual male. Within 6 months of initial presentation with a necrotizing ulcerative gingivitis, the lesion extended to a necrotizing ulcerative stomatitis involving the surroun...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1998.69.6.710
更新日期:1998-06-01 00:00:00
abstract:BACKGROUND:Lingual plate perforation at the time of implant placement in posterior mandible is a potential surgical complication, and presence of a lingual concavity is considered a risk factor. Little is known about the spatial relationship between implant and lingual plate. The role of lingual concavity in the risk o...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2010.100313
更新日期:2011-01-01 00:00:00
abstract::Interleukin-1 beta (IL-1 beta) is the predominant form of IL-1 produced by macrophages. IL-1 beta possesses numerous and diverse biological activities. Several of these activities, including fibroblast proliferation, potentiation of the immune response, and stimulation of bone resorption may be of relevance to the pat...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1991.62.1.36
更新日期:1991-01-01 00:00:00
abstract::A great deal of controversy has existed in the periodontal literature as to whether the site or the subject should be the unit of analysis. Using the site as the unit of analysis assumes that observations of sites within the same subject are independent and ignores between subject variation. The purpose of this report...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1992.63.6.507
更新日期:1992-06-01 00:00:00
abstract:BACKGROUND:Application of cone-beam computed tomography (CBCT) has grown exponentially across dentistry with a clear impact in implant dentistry. This review aims at providing the scientific context to understand if CBCT imaging should become the standard of care for patients requiring dental implants. METHODS:A liter...
journal_title:Journal of periodontology
pub_type: 杂志文章,评审
doi:10.1902/jop.2017.160548
更新日期:2017-10-01 00:00:00
abstract::The Orbison ultrasonic instrument and the Cavitron ultrasonic dental unit were compared for the smoothness of the root surfaces they produced. Twenty teeth were analyzed with the scanning electron microscope and classified as to rough or smooth. Both instruments produced similar degrees of smoothness on the root surfa...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1975.46.2.119
更新日期:1975-02-01 00:00:00
abstract::This study investigated a possible association between bruxism and severity of periodontal disease. Subjects consisted of 51 patients (mean age 47.3 years) referred to the Department of Periodontology for treatment of moderate to severe periodontal disease (Perio-group) and 40 patients (mean age 48.9 years) referred t...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1987.58.3.173
更新日期:1987-03-01 00:00:00
abstract:BACKGROUND:This study compares the levels of cytokines and bone-related factors in the gingival crevicular fluid (GCF) of systemically healthy patients with chronic periodontitis (CP); and better-controlled, and poorly controlled patients with type 2 diabetes and CP. METHODS:Thirty-seven patients with type 2 diabetes ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2011.100643
更新日期:2011-08-01 00:00:00
abstract:BACKGROUND:Enamel matrix derivative (EMD) has been shown to promote several aspects of periodontal regeneration in vitro and in vivo. Recently, a bioengineered tissue (DG) was developed to promote wound healing of chronic skin ulcers. This pilot study sought to assess the effects of EMD and DG, alone or in combination,...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2006.030264
更新日期:2006-05-01 00:00:00
abstract:BACKGROUND:Langerhans-cell histiocytosis (LCH) is a group of rare disorders histologically characterized by the proliferation of Langerhans cells. Multiple organs and systems may be involved by the disease. Typically, there is bone involvement and, less frequently, lesions may be found in the lungs, liver, lymph nodes,...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2005.76.1.143
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND:It has been shown that toll-like receptor (TLR) 2- and TLR4-stimulating abilities of supragingival plaque (SPP) are associated with periodontal conditions. It is hypothesized that SPP might affect the periodontium through its influence on subgingival plaque (SBP). This study investigates relationships betwee...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2016.150573
更新日期:2016-09-01 00:00:00
abstract::Interdental gingival tissues are designated inflamed on the basis of their color and bleeding after stimulation. Gingival bleeding was previously shown in histological studies to indicate the presence of inflammatory lesions. The present study was undertaken to determine associations between bleeding and visual signs ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1988.59.11.722
更新日期:1988-11-01 00:00:00
abstract:BACKGROUND:Transforming growth factor-beta (TGF-beta) interference with interleukin 6 (IL-6) activity and the role of the latter in early human embryonic development prompted us to examine the effects IL-6 on matrix synthesis and the effects of TGF-beta3 on IL-6 expression human cleft lip and palate (CLP) fibroblasts. ...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2003.74.10.1447
更新日期:2003-10-01 00:00:00
abstract:BACKGROUND:Generalized aggressive periodontitis is described as a clinical entity affecting both deciduous and permanent dentition with extensive alveolar bone loss, mobility, and exfoliation of all or many teeth. Controversy exists on dental implant use to restore missing dentition in younger patients. METHODS:This c...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2001.72.3.411
更新日期:2001-03-01 00:00:00
abstract::Throughout the 20th century, an understanding of the role of causative bacteria and the susceptible host in the initiation and progression of periodontal disease(s) has emerged from the research efforts of scientists and clinicians worldwide. Over time, specific bacterial types, such as Porphyromonas gingivalis, were ...
journal_title:Journal of periodontology
pub_type: 历史文章,杂志文章
doi:10.1902/jop.2008.080182
更新日期:2008-08-01 00:00:00
abstract::Tooth gliding occurs frequently both in the opening (55.9%) and closing (60.5%) chewing strokes. The average glide length was 1 mm. Good occlusions could not be distinguished from poor occlusion on the basis of frequency and length of gliding contacts. The greater the component of lateral movement during the closing s...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1976.47.6.331
更新日期:1976-06-01 00:00:00
abstract::Mycoplasma have been identified in one case of juvenile periodontitis by size, morphology, hemadsorption and cultural techniques. These microorganisms were found on the surface of the tooth, on the surface of pocket epithelium and invading the gingival epithelium and adjacent connective tissue. These observations sugg...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1984.55.10.574
更新日期:1984-10-01 00:00:00
abstract:BACKGROUND:The clinical success of root coverage with autogenous connective tissue (CT) or acellular dermal matrix (ADM) has been well documented. However, limited histological results of CT grafts have been reported, and a case report of a human block section has been published documenting an ADM graft. The purpose of...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1902/jop.2005.76.2.178
更新日期:2005-02-01 00:00:00
abstract:BACKGROUND:In patients with severe peridontitis, lower incisors are prone to terminal breakdown. This study assessed the longevity of composite-bonded resin/natural teeth (reinforced only with a stainless steel mesh) as replacements for periodontally lost lower incisors. METHODS:Besides the longevity of the restoratio...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1999.70.2.205
更新日期:1999-02-01 00:00:00
abstract::A double-blind study was undertaken to determine the effects of megadose ascorbic acid supplementation on plasma ascorbate levels, polymorphonuclear neutrophil (PMN) chemotaxis and clinical and biochemical determinations of inflammatory progression in individuals with a mean daily ascorbate intake level of approximate...
journal_title:Journal of periodontology
pub_type: 临床试验,杂志文章
doi:10.1902/jop.1986.57.8.472
更新日期:1986-08-01 00:00:00
abstract::Cyclosporine A (CsA) and verapamil are two agents used in renal transplantation, both of which are suspected of inducing gingival overgrowth. This study was conducted to investigate the effect of verapamil on the severity and prevalence of CsA-induced gingival overgrowth. Fifty-one (51) renal transplant recipients (to...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1996.67.11.1201
更新日期:1996-11-01 00:00:00
abstract::Studies of the inductive properties of human dentin and cementum have yielded differing results. Comparisons are difficult to draw because of variations in time, donor tissue, host immunologic status, implant site, decalcifying agents and degree of decalcification. Analysis of the many experiments intimates that the a...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1985.56.11.699
更新日期:1985-11-01 00:00:00
abstract:BACKGROUND:Low-calorie diets are commonplace for reducing body weight. However, no information is available on the effects of a reduced-calorie diet on periodontal inflammation and disease. The purpose of this study was to evaluate the clinical effects of a long-term calorie-restriction (CR) diet on periodontitis in an...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2008.070629
更新日期:2008-07-01 00:00:00
abstract::In this investigation periodontal destruction was produced by a combination of inflammatory and traumatic factors. After the inflammation was resolved and the trama stopped, a significant amount of alveolar bone regeneration took place. The implications of these findings for the management of advanced periodontal dise...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1976.47.12.687
更新日期:1976-12-01 00:00:00
abstract::The purpose of this study was to evaluate the healing potential of deep, primarily 3wall intrabony defects which were treated by flap debridement and expanded polytetrafluoroethylene (ePTFE) membranes and followed for extended time periods. All of the treated defects were in the mandibular arch. Thirty-two patients we...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1993.64.11s.1138
更新日期:1993-11-01 00:00:00
abstract:BACKGROUND:Prostaglandin E2 (PGE2) plays important roles in the pathogenesis of periodontal disease. Recent studies have revealed the existence of 2 isozymes of cyclooxygenase (COX), called COX-1 and COX-2. The purpose of the present study was to investigate the contribution of COX-1 and COX-2 to PGE2 production by hum...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2000.71.10.1575
更新日期:2000-10-01 00:00:00
abstract::Localized juvenile periodontitis (LJP) is an aggressive periodontal disease of familial nature. Neutrophils from a majority of patients with this disease exhibit decreased Chemotaxis with increased adherence, oxidative burst, and degranulation in response to opsonized bacteria. It is proposed that the biological basis...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.1996.67.3s.337
更新日期:1996-03-01 00:00:00
abstract:BACKGROUND:Cementum formation is considered to be a critical event for successful regeneration of periodontal tissues. Cementoblasts share many characteristics with osteoblasts. Prostaglandin E(2) (PGE(2)) is an important local factor in bone metabolism. Although the effects of PGE(2) on osteoblasts are well known, its...
journal_title:Journal of periodontology
pub_type: 杂志文章
doi:10.1902/jop.2006.060148
更新日期:2006-12-01 00:00:00