Autologous Platelet-Rich Fibrin in the Treatment of 3-Wall Intrabony Defects in Aggressive Periodontitis: A Randomized Controlled Clinical Trial.

Abstract:

BACKGROUND:Platelet-rich fibrin (PRF) has recently been applied in osseous regeneration. The aim of the present study is to explore the efficacy of PRF in treatment of intrabony defects (IBDs) in aggressive periodontitis. METHODS:Fifty-four IBDs in 17 patients were treated either with autologous PRF with open flap debridement (OFD) or OFD alone. Clinical and radiologic parameters such as probing depth (PD), clinical attachment level (CAL), IBD depth, and percentage defect change were recorded at baseline and 9 months postoperatively. RESULTS:Mean PD reduction and mean CAL gain were significantly greater in PRF compared with the control group. Furthermore, a significantly greater percentage of mean bone defect change was found in the PRF group. CONCLUSION:Within the limits of the present study, there is greater bone fill at sites treated with PRF with conventional OFD than conventional OFD alone.

journal_name

J Periodontol

authors

Bajaj P,Agarwal E,Rao NS,Naik SB,Pradeep AR,Kalra N,Priyanka N,Kumari M

doi

10.1902/jop.2017.120661

subject

Has Abstract

pub_date

2017-11-01 00:00:00

pages

1186-1191

issue

11

eissn

0022-3492

issn

1943-3670

journal_volume

88

pub_type

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