High Hydrostatic Pressure Therapy Annihilates Squamous Cell Carcinoma in a Murine Model.

abstract：:To identify novel susceptibility genes and gene sets for obesity, we conducted a genomewide expression association analysis of obesity via integrating genomewide association study (GWAS) and expression quantitative trait loci (eQTLs) data. GWAS summary data of body mass index (BMI) and waist-to-hip ratio (WHR) was dri...

journal_title：BioMed research international

authors： Liu L,Fan Q,Zhang F,Guo X,Liang X,Du Y,Li P,Wen Y,Hao J,Wang W,He A

更新日期：2018-05-08 00:00:00

abstract：:We study the interaction of 3T3 Swiss albino mouse fibroblasts with polymeric nanoparticles (NPs) and investigate cellular behaviour in terms of viability/cytotoxicity, cell cycle, NPs uptake, MAP kinase (ERK1/2), and focal adhesion kinase (FAK) activation. After incubation of NPs with cell culture media, western blot...

journal_title：BioMed research international

authors： Rosso F,Marino G,Grimaldi A,Cafiero G,Chiellini E,Chiellini F,Barbarisi M,Barbarisi A

更新日期：2013-01-01 00:00:00

abstract：Background:The predictive values of monocytes in the prognosis of patients with acute paraquat (PQ) poisoning are unclear. This retrospective study investigated the predictive values of monocytes in the prognosis of patients with acute PQ poisoning. Methods:Adult patients who suffered from acute PQ poisoning in the em...

journal_title：BioMed research international

authors： Zhao Y,Song YQ,Gao J,Feng SY,Li Y

更新日期：2019-07-15 00:00:00

abstract：:Puffer fishes were collected from the central sea in Vietnam from spring to summer season. The eggs were incubated in MRS broth that was used to test the toxicity in mice and isolate the lactic acid bacteria community that could produce tetrodotoxin (TTX). Thin layer chromatography (TLC) and high performance lipid chr...

journal_title：BioMed research international

authors： Nguyen TH,Nguyen HN,Nghe DV,Nguyen KH

更新日期：2015-01-01 00:00:00

abstract：:Introduction. Pelvic organ prolapse (POP) and urinary incontinence (UI) have increasing prevalence in the elderly population. The aim of this study was to compare the comorbidities of these procedures between <70 y/o and ≥70 y/o patients. Materials and Methods. In our retrospective study over a period of 2.5 years, 40...

journal_title：BioMed research international

authors： Joukhadar R,Wöckel A,Herr D,Paulus V,Radosa J,Hamza A,Solomayer E,Baum S

更新日期：2016-01-01 00:00:00

abstract：:Human diseases are abnormal medical conditions in which multiple biological components are complicatedly involved. Nevertheless, most contributions of research have been made with a single type of genetic data such as Single Nucleotide Polymorphism (SNP) or Copy Number Variation (CNV). Furthermore, epigenetic modifica...

journal_title：BioMed research international

authors： Kang M,Kim DC,Liu C,Gao J

更新日期：2015-01-01 00:00:00

abstract：:Reactive oxygen species (ROS) damage macromolecules and cellular components in nearly all kinds of cells and often generate toxic intracellular byproducts. In this work, aldehyde generation derived from the Escherichia coli membrane oxidation as well as membrane fatty acid profiles, protein oxidation, and bacterial re...

journal_title：BioMed research international

authors： Pradenas GA,Díaz-Vásquez WA,Pérez-Donoso JM,Vásquez CC

更新日期：2013-01-01 00:00:00

abstract：:Objectives. To construct a frailty index from next-of-kin information of the last year of life of community-dwelling 50 years old or older adults and test its association with health services utilization. Methods. Cross-sectional analysis from next-of-kin data available from the last wave of the Mexican Health and Agi...

journal_title：BioMed research international

authors： Pérez-Zepeda MU,Cesari M,Carrillo-Vega MF,Salinas-Escudero G,Tella-Vega P,García-Peña C

更新日期：2017-01-01 00:00:00

abstract：Background:Reduced baroreflex sensitivity (BRS) has been reported in patients with acute cardiovascular events. We tested the hypothesis that BRS varies in different subtypes of acute ischemic stroke (AIS) and that BRS is a predictor of clinical outcomes. Methods:We examined autonomic parameters in 34 patients with AI...

journal_title：BioMed research international

authors： Tsai WC,Lin HC,Lai YR,Hsu CW,Huang CC,Wang HC,Su CM,Su YJ,Lin WC,Cheng BC,Chang WN,Lu CH,Tsai NW

更新日期：2019-04-18 00:00:00

abstract：:Coconut palm (Cocos nucifera) is an important commercial crop in many tropical countries, but its industry generates large amounts of residue. One way to address this problem is to use this residue, coconut husk, to produce second-generation (2G) ethanol. The aim of this review is to describe the methods that have bee...

journal_title：BioMed research international

authors： Bolivar-Telleria M,Turbay C,Favarato L,Carneiro T,de Biasi RS,Fernandes AAR,Santos AMC,Fernandes PMB

更新日期：2018-09-27 00:00:00

abstract：Purpose:To study the effect of duodenal-jejunal omega switch (DJOS) in combination with different dietary patterns on the retinol-binding protein (RBP4), fetuin-A, and fibroblast growth factor 21 (FGF21) plasma levels and their hepatic gene expressions in rats. Methods:A high-fat diet (HF) was given to 28 rats and 28 ...

journal_title：BioMed research international

authors： Stygar D,Pigłowski W,Chełmecka E,Skrzep-Poloczek B,Sawczyn T,Garłowski W,Jochem J,Karcz KW

更新日期：2018-08-16 00:00:00

abstract：:Background. It has been suggested that, during pregnancy, endometriosis can cause a variety of disease-related complications. Objectives. The purpose of the study was to find out if women with histologically confirmed endometriosis do have a higher risk of adverse pregnancy outcome and if they suffer from a higher rat...

journal_title：BioMed research international

authors： Allerstorfer C,Oppelt P,Enzelsberger SH,Shamiyeh A,Schimetta W,Shebl OJ,Mayer RB

更新日期：2016-01-01 00:00:00

abstract：:Preterm birth remains the most prevalent cause of neonatal morbidity. This study aimed to evaluate the diagnostic value of SDF-1α, resistin, secretory RAGE (sRAGE), and endogenous secretory RAGE (esRAGE) in preterm labor. A total of 211 pregnant women participated in the study. Group A contained 72 women between 22 an...

journal_title：BioMed research international

authors： Rzepka R,Dołęgowska B,Rajewska A,Sałata D,Budkowska M,Kwiatkowski S,Torbé A

更新日期：2016-01-01 00:00:00

abstract：:The three-dimensional (3D) structures of the right atrial appendage (RAA) and left atrial appendage (LAA) were compared to clarify why thrombus formation less frequently occurs in RAA than in LAA. Morphological differences between RAA and LAA of 34 formalin-preserved cadaver hearts were investigated. Molds of RAA and ...

journal_title：BioMed research international

authors： Shinoda K,Hayashi S,Fukuoka D,Torii R,Watanabe T,Nakano T

更新日期：2016-01-01 00:00:00

abstract：:Hyperhomocysteinemia is an independent risk factor for cardiovascular diseases. The enhanced nitrative stress plays an important role in homocysteine-induced endothelial dysfunction. Previous studies have showed that phytoestrogen α -zearalanol alleviated endothelial injury in ovariectomized hyperhomocysteinemic rats;...

journal_title：BioMed research international

authors： Liu T,Hou DD,Zhao Q,Liu W,Zhen PP,Xu JP,Wang K,Huang HX,Li X,Zhang H,Xu HB,Wang W

更新日期：2013-01-01 00:00:00

abstract：:Recent work in preservation of female fertility as well as new information on the nature of spermatogonial stem cells has prompted an investigation into the possibility of an effective clinical-grade procedure for the cryopreservation of testicular cells and/or tissue. Clinical-grade reagents, validated equipment, and...

journal_title：BioMed research international

authors： Pacchiarotti J,Ramos T,Howerton K,Greilach S,Zaragoza K,Olmstead M,Izadyar F

更新日期：2013-01-01 00:00:00

abstract：:Mutations in the kinase domain of epidermal growth factor receptor (EGFR) have high levels of basal receptor phosphorylation and are associated with clinical responsiveness to Iressa in patients with nonsmall cell lung cancer (NSCLC). This study aimed to assess the feasibility of morpholino-[(124)I]IPQA derivative as ...

journal_title：BioMed research international

authors： Yeh SH,Lin CF,Kong FL,Wang HE,Hsieh YJ,Gelovani JG,Liu RS

更新日期：2013-01-01 00:00:00

abstract：:This paper represents data of long-term open prospective study. 312 male clean-up workers, who participated in elimination of the Chernobyl disaster consequences in 1986-87, were observed and examined in Moscow Research Institute of Psychiatry. The average age of patients was 57,0 ± 6,8 years. All patients were diagno...

journal_title：BioMed research international

authors： Krasnov V,Kryukov V,Samedova E,Emelianova I,Ryzhova I

更新日期：2015-01-01 00:00:00

abstract：:Large amounts of various biological networks exist for representing different types of interaction data, such as genetic, metabolic, gene regulatory, and protein-protein relationships. Recent approaches on biological network study are based on different mathematical concepts. It is necessary to construct a uniform fra...

journal_title：BioMed research international

authors： Cao Y,Xu W,Niu C,Bo X,Li F

更新日期：2017-01-01 00:00:00

abstract：:Psoriasis is one of the most prevalent immune mediated skin diseases worldwide. Despite the large prevalence in both men and women, the pathogenesis of this disease has not yet been fully clarified. Nowadays, it is believed that psoriasis is most likely a T helper Th1/Th17 induced inflammatory disease. Stressful life ...

journal_title：BioMed research international

authors： Ceovic R,Mance M,Bukvic Mokos Z,Svetec M,Kostovic K,Stulhofer Buzina D

更新日期：2013-01-01 00:00:00

abstract：:Local delivery of neurotrophic factors is a pillar of neural repair strategies in the peripheral nervous system. The main disadvantage of the free growth factors is their short half-life of few minutes. In order to prolong their activity, we have conjugated to iron oxide nanoparticles three neurotrophic factors: nerve...

journal_title：BioMed research international

authors： Ziv-Polat O,Shahar A,Levy I,Skaat H,Neuman S,Fregnan F,Geuna S,Grothe C,Haastert-Talini K,Margel S

更新日期：2014-01-01 00:00:00

abstract：:Background. The survival rates of in-hospital cardiac arrests (IHCAs) are reportedly low at night, but the difference between the survival rates of cardiac origin and noncardiac origin IHCAs occurring at night remains unclear. Methods. Outcomes of IHCAs during different shifts (night, day, and evening) were compared a...

journal_title：BioMed research international

authors： Syue YJ,Huang JB,Cheng FJ,Kung CT,Li CJ

更新日期：2016-01-01 00:00:00

abstract：:Angiopoietin-like protein 4 (ANGPTL4) is widely known as a key regulator of lipid metabolism. We investigated the relationship between ANGPTL4 expression in serum or urine and blood lipid or urine protein levels of patients with hyperlipidemia- (HL-) related proteinuria. Sixty-eight patients with HL-related proteinuri...

journal_title：BioMed research international

authors： Gao X,Zhang M,Feng W,Xu Z,Wang Y,Shi L,Zhang J

更新日期：2020-03-23 00:00:00

abstract：:Models using large animals that are suitable for studying artificial liver support system (ALSS) are urgently needed. Presently available acute liver failure (ALF) models mainly involve pigs or dogs. Establishment of current surgical ALF models (hepatectomy/devascularization) requires either very good surgical skills ...

journal_title：BioMed research international

authors： Cai L,Weng J,Feng L,He G,Qin J,Zhang Z,Li Y,Peng Q,Jiang Z,Pan M,Gao Y

更新日期：2016-01-01 00:00:00

abstract：Background:With the continuous improvement of the modernization of the Chinese military and the major adjustments made by the state to the recruitment policy, the newly recruited military undergone multiple pressures such as targeted high-intensity military training and environmental changes. The mental health of milit...

journal_title：BioMed research international

authors： Tao N,An H,Zhang J,Zhang Y,Jin L,Xu L,Liu J,Xu X

更新日期：2020-04-02 00:00:00

abstract：:Although a history of first-trimester recurrent spontaneous abortion (FRSA) is regarded as a risk factor in antenatal care, the characteristic of subsequent pregnancy outcome is not clearly elucidated. Here, a retrospective analysis was performed on the clinical data of 492 singleton pregnant women. 164 of them with t...

journal_title：BioMed research international

authors： Yang J,Wang Y,Wang XY,Zhao YY,Wang J,Zhao YY

更新日期：2017-01-01 00:00:00

abstract：:The 13 million nurses worldwide constitute most of the global healthcare workforce and are uniquely positioned to engage with others to address disparities in healthcare to achieve the goal of better health for all. A new vision for nurses involves active participation and collaboration with international colleagues a...

journal_title：BioMed research international

authors： Premji SS,Hatfield J

更新日期：2016-01-01 00:00:00

abstract：:Increased sugar consumption, especially fructose, is strongly related to the development of type 2 diabetes (T2D) and metabolic syndrome. The aim of this study was to evaluate long term effects of fructose supplementation on Wistar rats. Three-week-old male rats were randomly divided into 2 groups: control (C; n = 14)...

journal_title：BioMed research international

authors： Dupas J,Feray A,Goanvec C,Guernec A,Samson N,Bougaran P,Guerrero F,Mansourati J

更新日期：2017-01-01 00:00:00

abstract：:Mitochondrial uncoupling protein 2 (UCP2) is suggested to have a role in the development of nonalcoholic steatohepatitis (NASH). However, the mechanism remains unclear. Autophagy is an important mediator of many pathological responses. This study aims to investigate the relationship between UCP2 and hepatoma cells aut...

journal_title：BioMed research international

authors： Lou J,Wang Y,Wang X,Jiang Y

更新日期：2014-01-01 00:00:00

abstract：:Little is known about how small variations in ionic currents and Ca²⁺ and Na⁺ diffusion coefficients impact action potential and Ca²⁺ dynamics in rabbit ventricular myocytes. We applied sensitivity analysis to quantify the sensitivity of Shannon et al. model (Biophys. J., 2004) to 5%-10% changes in currents conductanc...

journal_title：BioMed research international

authors： Lo YH,Peachey T,Abramson D,McCulloch A,Michailova A

更新日期：2013-01-01 00:00:00