Uncoupling protein 2 regulates palmitic acid-induced hepatoma cell autophagy.

abstract：:Amylase is an industrially important enzyme and applied in many industrial processes such as saccharification of starchy materials, food, pharmaceutical, detergent, and textile industries. This research work deals with the optimization of fermentation conditions for α-amylase production from thermophilic bacterial str...

journal_title：BioMed research international

authors： Simair AA,Qureshi AS,Khushk I,Ali CH,Lashari S,Bhutto MA,Mangrio GS,Lu C

更新日期：2017-01-01 00:00:00

abstract：:In this paper, a novel small-molecular apoptotic PET imaging probe, (18)F-ML-8 with a malonate motif structure, is presented and discussed. After study, the small tracer that belongs to a member of ApoSense family is proved to be capable of imaging merely apoptotic regions in the CTX treated tumor-bearing mice. The ex...

journal_title：BioMed research international

authors： Yao S,Hu K,Tang G,Gao S,Tang C,Yao B,Nie D,Sun T,Jiang S

更新日期：2015-01-01 00:00:00

abstract：:WNT proteins are involved in embryonic development, sex determination, stem cell recruitment, angiogenesis, and cancer. They take part in morphological changes in the endometrium during development, regulate processes of endometrial proliferation and differentiation. This review presents current knowledge about implic...

journal_title：BioMed research international

authors： Kiewisz J,Wasniewski T,Kmiec Z

更新日期：2015-01-01 00:00:00

abstract：:Liver transplantation is the best treatment option for early-stage hepatocellular carcinoma, liver cirrhosis, fulminant liver failure, and end-stage liver diseases. Even though advances in surgical techniques and perioperative care have improved postoperative outcomes, perioperative cardiovascular complications are a ...

journal_title：BioMed research international

authors： Choi JM,Kong YG,Kang JW,Kim YK

更新日期：2017-01-01 00:00:00

abstract：:This study investigated the effect of cilostazol on proangiogenesis functions in human early endothelial progenitor cells (EPCs) in vitro and the therapeutic implication of hybrid therapy with cilostazol and human early EPCs in vivo. Cilostazol significantly increased colony-forming units and enhanced differentiation ...

journal_title：BioMed research international

authors： Tseng SY,Chao TH,Li YH,Cho CL

更新日期：2016-01-01 00:00:00

abstract：:As emerging tick born rickettsial diseases caused by A. phagocytophilum and E. chaffeensis, anaplasmosis and ehrlichiosis have become a serious threat to human and animal health throughout the world. In particular, in China, an unusual transmission of nosocomial cases of human granulocytic anaplasmosis occurred in Anh...

journal_title：BioMed research international

authors： Zhang L,Liu H,Xu B,Zhang Z,Jin Y,Li W,Lu Q,Li L,Chang L,Zhang X,Fan D,Cao M,Bao M,Zhang Y,Guan Z,Cheng X,Tian L,Wang S,Yu H,Yu Q,Wang Y,Zhang Y,Tang X,Yin J,Lao S,Wu B,Li J,Li W,Xu Q,Shi Y,Huan

更新日期：2014-01-01 00:00:00

abstract：:The different techniques and methods employed as well as the different quantitative and qualitative variables measured in order to objectify postural control are often chosen without taking into account the population studied, the objective of the postural test, and the environmental conditions. For these reasons, the...

journal_title：BioMed research international

authors： Paillard T,Noé F

更新日期：2015-01-01 00:00:00

abstract：:The aim of this study was to determine the capacity of biofilm formation of atypical enteropathogenic Escherichia coli (aEPEC) strains on abiotic and biotic surfaces. Ninety-one aEPEC strains, isolated from feces of children with diarrhea, were analyzed by the crystal violet (CV) assay on an abiotic surface after 24 h...

journal_title：BioMed research international

authors： Culler HF,Mota CM,Abe CM,Elias WP,Sircili MP,Franzolin MR

更新日期：2014-01-01 00:00:00

abstract：:CA-125 has been a valuable marker for the follow-up of ovarian cancer patients but it is not sensitive enough to be used as diagnostic marker. We had already used secretomic methods to identify proteins differentially secreted by serous ovarian cancer cells compared to healthy ovarian cells. Here, we evaluated the sec...

journal_title：BioMed research international

authors： Kramer M,Pierredon S,Ribaux P,Tille JC,Petignat P,Cohen M

更新日期：2015-01-01 00:00:00

abstract：Objective:To explore multiscale integrated analysis methods in identifying key regulators of esophageal cancer (ESCA). Methods:We downloaded the ESCA dataset from The Cancer Genome Atlas (TCGA) database, which contained RNA-seq data, miRNA-seq data, methylation data, and clinical phenotype information. Then, we combin...

journal_title：BioMed research international

authors： Xu Z,Wu Z,Zhang J,Zhou R,Wu J,Yu B

更新日期：2020-08-12 00:00:00

abstract：:One of the female causes of infertility is anovulation which is treatable with gonadotropin hormones. These hormones affect the molecular organization of the uterus such as glycoconjugates that are the first site of contact between the blastocyst and the uterus. The objective of this project was to study the alteratio...

journal_title：BioMed research international

authors： Aliabadi E,Makoolati Z,Talaei-Khozani T,Ardekani FM,Aliabadi A

更新日期：2020-12-04 00:00:00

abstract：Background:As the important components in polycomb repressive complexes 1 (PRC1) and heterochromatin protein 1 (HP1), Chromobox (CBX) family members are involved in epigenetic regulatory function, transcriptional repression, and other cellular metabolisms. Increasing studies have indicated significant associations betw...

journal_title：BioMed research international

authors： Chen ZY,Sun SX,Zhu SX,Bu J

更新日期：2020-11-05 00:00:00

abstract：:Two field isolates of Rhizoctonia solani were isolated from infected paddy plants in Malaysia. These isolates were verified via ITS-rDNA analysis that yielded ~720 bp products of the ITS1-5.8S-ITS4 region, respectively. The sequenced products showed insertion and substitution incidences which may result in strain dive...

journal_title：BioMed research international

authors： Nadarajah K,Omar NS,Rosli MM,Shin Tze O

更新日期：2014-01-01 00:00:00

abstract：Background:The reliability of blood pressure (BP) measurement in hospitalized patients is a topic of debate and the therapeutic implication of the routinely collected BP profiles is probably overestimated. When measurements are performed in elderly patients, further potential sources of misinterpretation occur. Method...

journal_title：BioMed research international

authors： Del Giorno R,Heiniger PS,Balestra L,Gabutti L

更新日期：2019-04-01 00:00:00

abstract：:The aim was to evaluate three different biodegradable polylactic acid- (PLA-) based osteosynthesis materials (OM). These OM (BioSorb, LactoSorb, and Delta) were used in 64 patients of whom 55 (85.9%) had fractures of the zygoma, five (7.8%) in the LeFort II level, two of the frontal bone (3.1%), and two of the maxilla...

journal_title：BioMed research international

authors： Kolk A,Köhnke R,Saely CH,Ploder O

更新日期：2015-01-01 00:00:00

abstract：:The aim of this study was to investigate whether osteopontin (OPN) variants are associated with susceptibility to ankylosing spondylitis (AS) in a Chinese population. Polymorphisms at the 9175th position in exon 7 of OPN and rs17524488 were genotyped using direct sequencing in 186 unrelated AS patients and 188 ethnica...

journal_title：BioMed research international

authors： Li J,Cai Y,Wang Z,Deng A,Yang G

更新日期：2018-01-18 00:00:00

abstract：Background:In resource limited settings, HIV/AIDS patients lack access to sufficient nutritious foods, which poses challenges to the success of antiretroviral therapy. HIV/AIDS and malnutrition are still major public health problems in Ethiopia. Though measuring nutritional status is an essential part of ART program, l...

journal_title：BioMed research international

authors： Gebremichael DY,Hadush KT,Kebede EM,Zegeye RT

更新日期：2018-05-06 00:00:00

abstract：:Technological processes in the dairy industry and the further passage through the gastrointestinal tract could impair viability and functionality of probiotic bifidobacteria. In the present work, the growth in milk of nine bifidobacterial strains shared by mother and child, their survival to freeze-drying and cold sto...

journal_title：BioMed research international

authors： Peirotén A,Gaya P,Arqués JL,Medina M,Rodríguez E

更新日期：2019-01-17 00:00:00

abstract：PURPOSE:Recovery of walking outdoors after hip fracture is important for equal participation in the community. The causes of poor recovery are not fully understood. This study investigates recovery of walking outdoors and associated determinants after hip fracture. METHODS:A prospective follow-up study, among clinical...

journal_title：BioMed research international

authors： Salpakoski A,Törmäkangas T,Edgren J,Sihvonen S,Pekkonen M,Heinonen A,Pesola M,Kallinen M,Rantanen T,Sipilä S

更新日期：2014-01-01 00:00:00

abstract：:Coronary computed tomography angiography (CCTA) has been recently evaluated for its ability to assess coronary plaque characteristics, including plaque composition. Identification of the relationship between plaque composition by CCTA and patient clinical presentations may provide insight into the pathophysiology of c...

journal_title：BioMed research international

authors： Sun Z,Xu L

更新日期：2014-01-01 00:00:00

abstract：INTRODUCTION:The aim of this report is to study the graft and patient survival in a large cohort of recipients with an analysis of factors that may affect the final outcomes. METHODS:Between March 1976 and March 2008, 1967 consecutive live-donor renal transplants were carried out. Various variables that may have an im...

journal_title：BioMed research international

authors： Ghoneim MA,Bakr MA,Refaie AF,Akl AI,Shokeir AA,Shehab El-Dein AB,Ammar HM,Ismail AM,Sheashaa HA,El-Baz MA

更新日期：2013-01-01 00:00:00

abstract：:Study of the probiotic potential of microorganisms isolated from fermented foods has been increasing, especially studies related to lactobacilli. In intestinal models, lactobacilli have demonstrated beneficial properties, such as anti-inflammatory activity and increased antibody production, but the molecular mechanism...

journal_title：BioMed research international

authors： Pessoa WFB,Melgaço ACC,de Almeida ME,Ramos LP,Rezende RP,Romano CC

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:This retrospective study was designed to investigate the efficacy and safety of intermittent portal triad clamping (PTC) with low central venous pressure (CVP) in liver resections. METHODS:Between January 2007 and August 2013, 115 patients underwent liver resection with intermittent PTC. The patients' data ...

journal_title：BioMed research international

authors： Topaloglu S,Yesilcicek Calik K,Calik A,Aydın C,Kocyigit S,Yaman H,Kutanis D,Karabulut E,Dohman D,Orem A,Arslan MK

更新日期：2013-01-01 00:00:00

abstract：:Recent studies have shown that sumoylation is a posttranslational modification involved in regulation of the transforming growth factor-β (TGF-β) signaling pathway, which plays a critical role in renal fibrosis in diabetic nephropathy (DN). However, the role of sumoylation in the regulation of TGF-β signaling in DN is...

journal_title：BioMed research international

authors： Zhou X,Gao C,Huang W,Yang M,Chen G,Jiang L,Gou F,Feng H,Ai N,Xu Y

更新日期：2014-01-01 00:00:00

abstract：:Caudal epidural block is a commonly used technique for surgical anesthesia in children and chronic pain management in adults. It is performed by inserting a needle through the sacral hiatus to gain entrance into the sacral epidural space. Using conventional blind technique, the failure rate of caudal epidural block in...

journal_title：BioMed research international

authors： Kao SC,Lin CS

更新日期：2017-01-01 00:00:00

abstract：Background:In vitro fertilization and embryo transfer (IVF-ET) technology has been widely used in the therapy of refractory infertility. Previous studies showed that acupuncture can effectively increase the clinical pregnancy rate of IVF-ET. However, the molecular mechanism is unknown. Materials and Methods:In this st...

journal_title：BioMed research international

authors： Cheng J,Jin X,Shen J,Mu Y,Li Q,Xia L,Gao Y,Xia Y

更新日期：2019-05-28 00:00:00

abstract：Background:Diabetes mellitus (DM) is a common disease that has an adverse impact on most orthopedic surgeries, and its prevalence has gradually increased in recent years. We aim to investigate the influence of DM on comorbidities and complications of patients undergoing primary total lower extremity arthroplasty. Meth...

journal_title：BioMed research international

authors： Qin W,Huang X,Yang H,Shen M

更新日期：2020-12-15 00:00:00

abstract：:Perinatal infections have a negative impact on brain development. However, the underlying mechanisms leading to neurological impairment are not completely understood and reliable models of inflammation are urgently needed. Using phorbol-myristate-acetate as an activator of inflammation, we investigated the effect on t...

journal_title：BioMed research international

authors： Dzietko M,Hahnemann M,Polley O,Sifringer M,Felderhoff-Mueser U,Bührer C

更新日期：2015-01-01 00:00:00

abstract：:Exosomal miRNAs are currently being explored as a novel class of biomarkers in cardiovascular diseases. However, few reports have focused on the value of circulating exosomal miRNAs as biomarkers for stable coronary artery disease (SCAD). Here, we aimed to investigate whether miRNAs involved in cardiovascular diseases...

journal_title：BioMed research international

authors： Zhang P,Liang T,Chen Y,Wang X,Wu T,Xie Z,Luo J,Yu Y,Yu H

更新日期：2020-12-11 00:00:00

abstract：:Human dental pulp stem cells (DPSCs) hold great promise in bone regeneration. However, the exact mechanism of osteogenic differentiation of DPSCs remains unknown, especially the role of exosomes played in. The DPSCs were cultured and received osteogenic induction; then, exosomes from osteogenic-induced DPSCs (OI-DPSC-...

journal_title：BioMed research international

authors： Xie L,Guan Z,Zhang M,Lyu S,Thuaksuban N,Kamolmattayakul S,Nuntanaranont T

更新日期：2020-09-28 00:00:00