Cellular Response of Sinorhizobium sp. Strain A2 during Arsenite Oxidation.

Abstract:

:Arsenic (As) is a widely distributed toxic element in the environment and microorganisms have developed resistance mechanisms in order to tolerate it. The cellular response of the chemoorganotrophic arsenite (As[III])-oxidizing α-Proteobacteria, Sinorhizobium sp. strain A2, to arsenic was examined in the present study. Several proteins associated with arsenite oxidase and As resistance were shown to be accumulated in the presence of As(III). A shift in central carbon metabolism from the tricarboxylic acid pathway to glyoxylate pathway was also observed in response to oxidative stress. Our results revealed the strategy of the As(III)-oxidizing Sinorhizobium strain to mitigate arsenic toxicity and oxidative damage by multiple metabolic adaptations.

journal_name

Microbes Environ

authors

Fukushima K,Huang H,Hamamura N

doi

10.1264/jsme2.ME15096

subject

Has Abstract

pub_date

2015-01-01 00:00:00

pages

330-4

issue

4

eissn

1342-6311

issn

1347-4405

journal_volume

30

pub_type

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