Abstract:
:Smart materials that are capable of memorizing a temporary shape, and morph in response to a stimulus, have the potential to revolutionize medicine and robotics. Here, we introduce an innovative method to program protein hydrogels and to induce shape changes in aqueous solutions at room temperature. We demonstrate our approach using hydrogels made from serum albumin, the most abundant protein in the blood plasma, which are synthesized in a cylindrical or flower shape. These gels are then programmed into a spring or a ring shape, respectively. The programming is performed through a marked change in stiffness (of up to 17-fold), induced by adsorption of Zn2+ or Cu2+ cations. We show that these programmed biomaterials can then morph back into their original shape, as the cations diffuse outside the hydrogel material. The approach demonstrated here represents an innovative strategy to program protein-based hydrogels to behave as actuators.
journal_name
Sci Advjournal_title
Science advancesauthors
Khoury LR,Slawinski M,Collison DR,Popa Idoi
10.1126/sciadv.aba6112subject
Has Abstractpub_date
2020-04-29 00:00:00pages
eaba6112issue
18issn
2375-2548pii
aba6112journal_volume
6pub_type
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