Pre-treatment graph measures of a functional semantic network are associated with naming therapy outcomes in chronic aphasia.

Abstract:

:Naming treatment outcomes in post-stroke aphasia are variable and the factors underlying this variability are incompletely understood. In this study, 26 patients with chronic aphasia completed a semantic judgment fMRI task before receiving up to 12 weeks of naming treatment. Global (i.e., network-wide) and local (i.e., regional) graph theoretic measures of pre-treatment functional connectivity were analyzed to identify differences between patients who responded most and least favorably to treatment (i.e., responders and nonresponders) and determine if network measures predicted naming improvements. Responders had higher levels of global integration (i.e., average network strength and global efficiency) than nonresponders, and these measures predicted treatment effects after controlling for lesion volume and age. Group differences in local measures were identified in several regions associated with a variety of cognitive functions. These results suggest there is a meaningful and possibly prognostically-informative relationship between patients' functional network properties and their response to naming therapy.

journal_name

Brain Lang

journal_title

Brain and language

authors

Johnson JP,Meier EL,Pan Y,Kiran S

doi

10.1016/j.bandl.2020.104809

subject

Has Abstract

pub_date

2020-08-01 00:00:00

pages

104809

eissn

0093-934X

issn

1090-2155

pii

S0093-934X(20)30068-7

journal_volume

207

pub_type

杂志文章
  • Three kinds of rhymes: An ERP study.

    abstract::In a simple prime-target visual rhyming paradigm, pairs of words, nonwords, and single letters elicited similar event-related potential (ERP) rhyming effects in young adults. Within each condition, primes elicited contingent negative variation (CNV) while nonrhyming targets elicited more negative waveforms than rhymin...

    journal_title:Brain and language

    pub_type: 杂志文章

    doi:10.1016/j.bandl.2007.06.003

    authors: Coch D,Hart T,Mitra P

    更新日期:2008-03-01 00:00:00

  • Lexicality and modality effects on evoked potentials in a memory-scanning task.

    abstract::Event-related potentials, as well as reaction times and performance accuracies, were recorded from normal young adults during the performance of a memory-scanning task, in response to the first and second items of the memorized set and to the probe. Stimuli included computer-generated digits, presented by earphones as...

    journal_title:Brain and language

    pub_type: 杂志文章

    doi:10.1006/brln.1994.1019

    authors: Pratt H,Erez A,Geva AB

    更新日期:1994-04-01 00:00:00

  • Event-related brain potentials elicited during phonological processing differentiate subgroups of reading disabled adolescents.

    abstract::Visual and auditory rhyme judgment tasks were administered to adolescent dyslexics and normal readers while event-related brain potentials were recorded. Reading disabled subjects were split into two groups based on a median split of scores on a visual non-word decoding test. The better decoders were called Phonetics ...

    journal_title:Brain and language

    pub_type: 杂志文章

    doi:10.1006/brln.1997.1893

    authors: McPherson WB,Ackerman PT,Holcomb PJ,Dykman RA

    更新日期:1998-04-01 00:00:00

  • The production of semantic paralexias in a Spanish-speaking aphasic.

    abstract::A case of a Spanish-speaking aphasic patient who produced a great number of semantic paralexias in reading aloud and who showed other symptoms consistent with the diagnosis of deep dyslexia is presented. In this study, (a) the production of semantic paralexias and the features of the deep dyslexia syndrome which have ...

    journal_title:Brain and language

    pub_type: 杂志文章

    doi:10.1006/brln.1995.1026

    authors: Ferreres AR,Miravalles G

    更新日期:1995-05-01 00:00:00

  • Exploring the cognitive basis of right-hemisphere pragmatic language disorders.

    abstract::Despite considerable interest in the linguistic dimensions of right-hemisphere (RH) pragmatic language disorders, the cognitive bases for these are rarely examined. This study investigated two alternative explanations. First, RH pragmatic language disorders may reflect failure of the RH to synthesise incoming and pree...

    journal_title:Brain and language

    pub_type: 杂志文章

    doi:10.1006/brln.2000.2342

    authors: McDonald S

    更新日期:2000-10-15 00:00:00

  • Developmental dyslexia and discrimination in speech perception: a dynamic model study.

    abstract::At the behavioral level one of the primary disturbances involved in congenital dyslexia concerns phonological processing. At the neuroarchitectural level autopsies have revealed ectopies, e.g., a reduced number of neurons in the upper layers of the cortex and an increased number in the lower ones. In dynamic models of...

    journal_title:Brain and language

    pub_type: 杂志文章

    doi:10.1016/s0093-934x(02)00592-8

    authors: Been PH,Zwarts F

    更新日期:2003-09-01 00:00:00

  • Duration of auditory sensory memory in parents of children with SLI: a mismatch negativity study.

    abstract::In a previous behavioral study, we showed that parents of children with SLI had a subclinical deficit in phonological short-term memory. Here, we tested the hypothesis that they also have a deficit in nonverbal auditory sensory memory. We measured auditory sensory memory using a paradigm involving an electrophysiologi...

    journal_title:Brain and language

    pub_type: 杂志文章

    doi:10.1016/j.bandl.2007.02.006

    authors: Barry JG,Hardiman MJ,Line E,White KB,Yasin I,Bishop DV

    更新日期:2008-01-01 00:00:00

  • Neurofunctional (re)organization underlying narrative discourse processing in aging: evidence from fNIRS.

    abstract::Relatively few studies have analyzed the mechanisms underlying the cognitive changes that affect language in the elderly, and fewer have done so for narrative discourse. The goal of this study was to explore the neurofunctional changes associated with aging for different components of narrative discourse. Functional n...

    journal_title:Brain and language

    pub_type: 杂志文章

    doi:10.1016/j.bandl.2011.09.008

    authors: Scherer LC,Fonseca RP,Giroux F,Senhadji N,Marcotte K,Tomitch LM,Benali H,Lesage F,Ska B,Joanette Y

    更新日期:2012-05-01 00:00:00

  • Event-related potentials and the phonological matching of picture names.

    abstract::Event-related potentials (ERPs) were recorded from one midline and three pairs of lateral electrodes while subjects determined whether a pair of sequentially presented pictures had rhyming or nonrhyming names. During the 1.56-sec interval between the two pictures, the slow ERP wave recorded over the left hemisphere wa...

    journal_title:Brain and language

    pub_type: 杂志文章

    doi:10.1016/0093-934x(90)90125-z

    authors: Barrett SE,Rugg MD

    更新日期:1990-04-01 00:00:00

  • Spatiotemporal dynamics of speech sound perception in chronic developmental stuttering.

    abstract::High-density ERPs were recorded in eight adults with persistent developmental stuttering (PERS) and eight matched normally fluent (CONT) control volunteers while participants either repeatedly uttered the vowel 'ah' or listened to their own previously recorded vocalizations. The fronto-central N1 auditory wave was red...

    journal_title:Brain and language

    pub_type: 杂志文章

    doi:10.1016/j.bandl.2010.07.007

    authors: Liotti M,Ingham JC,Takai O,Paskos DK,Perez R,Ingham RJ

    更新日期:2010-11-01 00:00:00

  • Verb retrieval and sentence production in aphasia.

    abstract::This paper presents a subject with a selective verb retrieval deficit. Nouns were produced more successfully than verbs in spontaneous speech, picture naming and when naming to definition. The word class effect was not observed in comprehension tasks, reading aloud or writing. This indicated that it was due to a speci...

    journal_title:Brain and language

    pub_type: 杂志文章

    doi:10.1006/brln.1998.1949

    authors: Marshall J,Pring T,Chiat S

    更新日期:1998-06-15 00:00:00

  • Aphasia for Morse code.

    abstract::The ability to communicate by Morse code at high speed has, to our knowledge, not been localized within the cerebral cortex, but might be suspected as residing within the left (dominant) hemisphere. We report a case of a 54-year-old male who suffered a left temporal tip intracerebral hematoma and who temporarily lost ...

    journal_title:Brain and language

    pub_type: 杂志文章

    doi:10.1016/0093-934x(86)90014-3

    authors: Wyler AR,Ray MW

    更新日期:1986-03-01 00:00:00

  • Visual field asymmetries for rhyme and syntactic category judgments in monolinguals and fluent early and late bilinguals.

    abstract::A tachistoscopic study investigated hemispheric specialization among monolingual and fluent French-English bilingual adults for speeded rhyme and syntactic category matching. A right visual field superiority was obtained for both types of verbal judgments. This effect was more pronounced in late bilinguals than in ear...

    journal_title:Brain and language

    pub_type: 杂志文章

    doi:10.1016/0093-934x(87)90102-7

    authors: Vaid J

    更新日期:1987-03-01 00:00:00

  • Early effects of neighborhood density and phonotactic probability of spoken words on event-related potentials.

    abstract::All current models of spoken word recognition propose that sound-based representations of spoken words compete with, or inhibit, one another during recognition. In addition, certain models propose that higher probability sublexical units facilitate recognition under certain circumstances. Two experiments were conducte...

    journal_title:Brain and language

    pub_type: 杂志文章

    doi:10.1016/j.bandl.2013.09.006

    authors: Hunter CR

    更新日期:2013-12-01 00:00:00

  • Language development in children with simple-partial left-hemisphere epilepsy.

    abstract::The nature of cerebral involvement in the acquisition of language was addressed in this longitudinal study of children with an early diagnosis of epilepsy with simple-partial seizures (SPE) and with epileptogenic foci localized in the left frontal (LF) lobe. Yearly evaluations of six SPE-LF children on tests of lingui...

    journal_title:Brain and language

    pub_type: 杂志文章

    doi:10.1006/brln.1998.1981

    authors: Cohen H,Le Normand MT

    更新日期:1998-10-01 00:00:00

  • Decreased white-matter density in a left-sided fronto-temporal network in children with developmental language disorder: evidence for anatomical anomalies in a motor-language network.

    abstract::The neurophysiological and neuroanatomical foundations of developmental language disorder (DLD) are still a matter of dispute. A main argument is that children with DLD show atypical anatomical asymmetries of speech-relevant brain areas, which possibly affect efficient language processing. In contrast to previous anat...

    journal_title:Brain and language

    pub_type: 杂志文章

    doi:10.1016/j.bandl.2006.08.003

    authors: Jäncke L,Siegenthaler T,Preis S,Steinmetz H

    更新日期:2007-07-01 00:00:00

  • Verbal fluency output in children aged 7-16 as a function of the production criterion: qualitative analysis of clustering, switching processes, and semantic network exploitation.

    abstract::Developmental changes in children's verbal fluency were explored in this study. One hundred and forty children aged from 7 to 16 completed four verbal fluency tasks, each with a different the production criterion (letter, sound, semantic, and free). The age differences were analyzed both in terms of number of words pr...

    journal_title:Brain and language

    pub_type: 杂志文章

    doi:10.1016/S0093-934X(03)00367-5

    authors: Sauzéon H,Lestage P,Raboutet C,N'Kaoua B,Claverie B

    更新日期:2004-04-01 00:00:00

  • The neural correlates of statistical learning in a word segmentation task: An fMRI study.

    abstract::Functional magnetic resonance imaging (fMRI) was used to assess neural activation as participants learned to segment continuous streams of speech containing syllable sequences varying in their transitional probabilities. Speech streams were presented in four runs, each followed by a behavioral test to measure the exte...

    journal_title:Brain and language

    pub_type: 杂志文章

    doi:10.1016/j.bandl.2012.11.007

    authors: Karuza EA,Newport EL,Aslin RN,Starling SJ,Tivarus ME,Bavelier D

    更新日期:2013-10-01 00:00:00

  • The mirror neuron system and action recognition.

    abstract::Mirror neurons, first described in the rostral part of monkey ventral premotor cortex (area F5), discharge both when the animal performs a goal-directed hand action and when it observes another individual performing the same or a similar action. More recently, in the same area mirror neurons responding to the observat...

    journal_title:Brain and language

    pub_type: 杂志文章,评审

    doi:10.1016/S0093-934X(03)00356-0

    authors: Buccino G,Binkofski F,Riggio L

    更新日期:2004-05-01 00:00:00

  • ERP correlates of language-specific processing of auditory pitch feedback during self-vocalization.

    abstract::The present study investigated whether the neural correlates for auditory feedback control of vocal pitch can be shaped by tone language experience. Event-related potentials (P2/N1) were recorded from adult native speakers of Mandarin and Cantonese who heard their voice auditory feedback shifted in pitch by -50, -100,...

    journal_title:Brain and language

    pub_type: 杂志文章

    doi:10.1016/j.bandl.2012.02.004

    authors: Chen Z,Liu P,Wang EQ,Larson CR,Huang D,Liu H

    更新日期:2012-04-01 00:00:00

  • The content of narrative discourse in children and adolescents after early-onset hydrocephalus and in normally developing age peers.

    abstract::The development of narrative content was studied in 100 children aged 6-15 years (49 with early-onset hydrocephalus and 51 age-matched controls) by analyzing transcripts of oral texts produced from their narrations of two fairy tales. In relation to those of their age-matched peers, the narratives of the children with...

    journal_title:Brain and language

    pub_type: 杂志文章,评审

    doi:10.1006/brln.1994.1008

    authors: Dennis M,Jacennik B,Barnes MA

    更新日期:1994-01-01 00:00:00

  • The mass/count distinction: evidence from on-line psycholinguistic performance.

    abstract::Under the hypothesis that the mass/count distinction in English is marked by a monovalent lexical feature, this article investigates whether features, lexical or morphosyntactic, play a role in simple lexical decision. Research findings have yet to settle how many features are accessed during lexical decision and to w...

    journal_title:Brain and language

    pub_type: 杂志文章

    doi:10.1006/brln.1999.2081

    authors: Gillon B,Kehayia E,Taler V

    更新日期:1999-06-01 00:00:00

  • An examination of impaired acoustic-phonetic processing in aphasia.

    abstract::This research examines the nature of acoustic-phonetic impairments found in aphasia, and the reliability of patient performance on phoneme discrimination and identification tasks. Aphasic patients were tested on three phoneme discrimination tasks examining their ability to discriminate items on the basis of contrasts ...

    journal_title:Brain and language

    pub_type: 杂志文章

    doi:10.1006/brln.1996.0019

    authors: Gow DW Jr,Caplan D

    更新日期:1996-02-01 00:00:00

  • Referential cohesion and logical coherence of narration after right hemisphere stroke.

    abstract::A group with right hemisphere dysfunction was compared to neurologically intact controls regarding the referential cohesion and logical coherence of narrative production. A somewhat varied sample of six stories was obtained with tasks of cartoon-elicited story-telling and auditory-oral retelling. We found deficits in ...

    journal_title:Brain and language

    pub_type: 杂志文章

    doi:10.1006/brln.1997.1741

    authors: Davis GA,O'Neil-Pirozzi TM,Coon M

    更新日期:1997-02-01 00:00:00

  • Language localization in cases of left temporal lobe arachnoid cyst: evidence against interhemispheric reorganization.

    abstract::We investigated whether left-hemisphere arachnoid cysts lead to reorganization of the language function using PET. A group analysis demonstrated that patients showed no more right-hemisphere activation than a matched control group. Several patients had clear language localizations in the left hemisphere during languag...

    journal_title:Brain and language

    pub_type: 杂志文章

    doi:10.1006/brln.2000.2358

    authors: Stowe LA,Go KG,Pruim J,den Dunnen W,Meiners LC,Paans AM

    更新日期:2000-12-01 00:00:00

  • Seeing Chinese characters in action: an fMRI study of the perception of writing sequences.

    abstract::The Chinese character is composed of a finite set of strokes whose order in writing follows consensual principles and is learnt through school education. Using functional magnetic resonance imaging (fMRI), this study investigates the neural activity associated with the perception of writing sequences by asking partici...

    journal_title:Brain and language

    pub_type: 杂志文章

    doi:10.1016/j.bandl.2010.11.007

    authors: Yu H,Gong L,Qiu Y,Zhou X

    更新日期:2011-11-01 00:00:00

  • The treatment of anomia resulting from output lexical damage: analysis of two cases.

    abstract::This study describes a treatment project, carried out with two anomic subjects, RBO and GMA failed to name pictures correctly as a consequence of damage to phonological lexical forms; their ability to process word meaning was unimpaired. Words that were consistently comprehended correctly, but produced incorrectly by ...

    journal_title:Brain and language

    pub_type: 杂志文章

    doi:10.1006/brln.1996.0008

    authors: Miceli G,Amitrano A,Capasso R,Caramazza A

    更新日期:1996-01-01 00:00:00

  • Agrammatism as evidence about grammar.

    abstract::A variety of experimental paradigms has yielded surprisingly fine-grained evidence about the kinds of syntactic information to which agrammatic aphasics are sensitive. This paper contrasts three accounts of agrammatism which draw quite different conclusions about the implications of this disorder for normal function: ...

    journal_title:Brain and language

    pub_type: 杂志文章,评审

    doi:10.1006/brln.1995.1040

    authors: Linebarger MC

    更新日期:1995-07-01 00:00:00

  • Social cognition after head injury: sarcasm and theory of mind.

    abstract::Closed head injury (CHI) is associated with communication difficulties in everyday social interactions. Previous work has reported impaired comprehension of sarcasm, using sarcastic remarks where the intended meaning is the opposite of the sincere or literal meaning. Participants with CHI in the present study were ass...

    journal_title:Brain and language

    pub_type: 杂志文章

    doi:10.1016/j.bandl.2004.09.002

    authors: Channon S,Pellijeff A,Rule A

    更新日期:2005-05-01 00:00:00

  • Effects of imposed delay of response and item complexity on auditory comprehension by aphasics.

    abstract::Ten aphasic and five control subjects were administered an auditory comprehension task similar to Levels I-IV of the Revised Token Test under conditions of 0, 5, 10, and 20 sec of imposed response delay. Responses were evaluated in terms of performance accuracy and response time. Aphasic subjects' response accuracy wa...

    journal_title:Brain and language

    pub_type: 杂志文章

    doi:10.1016/0093-934x(86)90054-4

    authors: Schulte E

    更新日期:1986-11-01 00:00:00