Abstract：
:The neurophysiological and neuroanatomical foundations of developmental language disorder (DLD) are still a matter of dispute. A main argument is that children with DLD show atypical anatomical asymmetries of speech-relevant brain areas, which possibly affect efficient language processing. In contrast to previous anatomical studies in DLD children, this study employed voxel based morphometry (VBM) in order to search for brain anomalies outside the classical language areas. Children with DLD (n=21) and healthy children (n=21) matched for age, sex, hand preference, and education were studied using high-resolution MRI scans. Using a new variant of the voxel-based morphometry technique (augmented VBM), the brains of children with DLD and control children were compared with respect to white matter (WM) and grey matter (GM) differences. In addition, simple hand motor tests were used to uncover possible motor impairments in DLD children. We found decreased WM volumes in a left-hemispheric network comprising the motor cortex, the dorsal premotor cortex, the ventral premotor cortex, and the planum polare on the superior temporal gyrus. In addition, DLD children exhibited motor impairments in most of the applied motor tests. These results provide strong evidence that children with DLD have anomalous anatomy in a left-sided network comprising motor and language areas. Thus, this study supports the suggestion that motor and language functions are equally impaired because the underlying anatomical underpinnings are regionally identical.
journal_name
Brain Langjournal_title
Brain and languageauthors
Jäncke L,Siegenthaler T,Preis S,Steinmetz Hdoi
10.1016/j.bandl.2006.08.003subject
Has Abstractpub_date
2007-07-01 00:00:00pages
91-8issue
1eissn
0093-934Xissn
1090-2155pii
S0093-934X(06)00386-5journal_volume
102pub_type
杂志文章abstract：:Prior research on the neural bases of syntactic comprehension suggests that activation in the left inferior frontal gyrus (lIFG) correlates with the processing of word order variations. However, there are inconsistencies with respect to the specific subregion within the IFG that is implicated by these findings: the pa...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/j.bandl.2010.06.004
更新日期：2012-02-01 00:00:00
abstract：:Despite anecdotal data on lexical interference among the languages of multilingual speakers, little research evidence about the lexical connections among multilinguals' languages exists to date. In the present paper, two experiments with a multilingual speaker who had suffered aphasia are reported. The first experimen...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/j.bandl.2006.05.004
更新日期：2006-08-01 00:00:00
abstract：:Published 100 years ago, Freud's monograph on aphasia, Zur Auffassung der Aphasien, is an incisive analysis of the so-called diagram-makers, those aphasiologists who would reduce brain and language to simple schemes of circumscribed cortical centers linked by unidirectional subcortical pathways. Chief architects of th...
journal_title：Brain and language
pub_type： 传,历史文章,杂志文章
doi：10.1016/0093-934x(92)90019-b
更新日期：1992-07-01 00:00:00
abstract：:Recent research suggests that there is a processing distinction between consonants and vowels in visual-word recognition. Here we conjointly examine the time course of consonants and vowels in processes of letter identity and letter position assignment. Event related potentials (ERPs) were recorded while participants ...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/j.bandl.2010.09.006
更新日期：2011-09-01 00:00:00
abstract：:Voicing is an important phonetic dimension that distinguishes voiced (i.e., /b/) from voiceless-aspirated stop consonants (i.e.,/ph/) in English. Perception of discrete voicing categories is affected by a number of acoustic cues. The present paper reviews evidence from brain-damaged populations indicating that the per...
journal_title：Brain and language
pub_type： 杂志文章,评审
doi：10.1006/brln.1997.1836
更新日期：1997-03-01 00:00:00
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journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/j.bandl.2010.11.007
更新日期：2011-11-01 00:00:00
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journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/0093-934x(90)90144-6
更新日期：1990-10-01 00:00:00
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journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/j.bandl.2018.10.002
更新日期：2019-01-01 00:00:00
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journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/j.bandl.2012.04.012
更新日期：2012-08-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/s0093-934x(02)00501-1
更新日期：2003-03-01 00:00:00
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journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/j.bandl.2012.06.008
更新日期：2012-10-01 00:00:00
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journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/0093-934x(91)90122-h
更新日期：1991-02-01 00:00:00
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journal_title：Brain and language
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.bandl.2018.11.002
更新日期：2019-01-01 00:00:00
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journal_title：Brain and language
pub_type： 杂志文章
doi：10.1006/brln.1999.2162
更新日期：1999-11-01 00:00:00
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journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/j.bandl.2015.12.003
更新日期：2016-02-01 00:00:00
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journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/j.bandl.2013.11.004
更新日期：2014-02-01 00:00:00
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journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/0093-934x(92)90109-r
更新日期：1992-10-01 00:00:00
abstract：:This study investigates the role of the temporal lobes in levels-of-processing tasks (phonetic and semantic encoding) according to the nature of recall tasks (free and cued recall). These tasks were administered to 48 patients with unilateral temporal epilepsy (right "RTLE"=24; left "LTLE"=24) and a normal group (n=24...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/S0093-934X(03)00303-1
更新日期：2004-04-01 00:00:00
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journal_title：Brain and language
pub_type： 杂志文章
doi：10.1006/brln.1996.0008
更新日期：1996-01-01 00:00:00
abstract：:The present case continues the series of anomia treatment studies with contextual priming (CP), being the second in-depth treatment study conducted for an individual suffering from semantically based anomia. Our aim was to acquire further evidence of the facilitation and interference effects of the CP treatment on sem...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/j.bandl.2005.02.003
更新日期：2005-11-01 00:00:00
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journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/j.bandl.2020.104905
更新日期：2021-01-19 00:00:00
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journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/j.bandl.2018.12.006
更新日期：2019-02-01 00:00:00
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journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/0093-934x(83)90052-4
更新日期：1983-05-01 00:00:00
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journal_title：Brain and language
pub_type： 杂志文章,评审
doi：10.1016/j.bandl.2015.01.003
更新日期：2015-09-01 00:00:00
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journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/0093-934x(83)90045-7
更新日期：1983-11-01 00:00:00
abstract：:Gestural communication is a modality considered in the literature as a candidate for determining the ancestral prerequisites of the emergence of human language. As reported in captive chimpanzees and human children, a study in captive baboons revealed that a communicative gesture elicits stronger degree of right-hand ...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/j.bandl.2008.10.004
更新日期：2009-03-01 00:00:00
abstract：:The role of fronto-striatal regions in processing different language rules such as semantic and (grapho) phonological ones is still under debate. We have recently developed a lexical analog of the Wisconsin card sorting task which measures set-shifting abilities where the visual rules color, number, shape were replace...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/j.bandl.2011.08.002
更新日期：2013-06-01 00:00:00
abstract：:It has often been suggested that the role of Broca's region in sentence comprehension can be explained with reference to general cognitive mechanisms (e.g. working memory, cognitive control). However, the (language-related) basis for such proposals is often restricted to findings on English. Here, we argue that an ext...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/j.bandl.2009.09.004
更新日期：2009-12-01 00:00:00
abstract：:The understanding of stories requires sensitivity to structural aspects of narrative, the emotional content conveyed by the narrative, and the interaction between structural and emotional facets of the story. Right-hemisphere-damaged (RHD) and normal control subjects performed a number of different analytic tasks whic...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/0093-934x(92)90104-m
更新日期：1992-04-01 00:00:00
abstract：:During speech perception, listeners compensate for phonological rules of their language. For instance, English place assimilation causes green boat to be typically pronounced as greem boat; English listeners, however, perceptually compensate for this rule and retrieve the intended sound (n). Previous research using EE...
journal_title：Brain and language
pub_type： 杂志文章
doi：10.1016/j.bandl.2015.06.009
更新日期：2015-10-01 00:00:00
