Dissociation of mechanisms of reading in Alzheimer's disease.

Abstract:

:The role of spelling-to-sound correspondence rules in oral word reading was investigated by asking patients with Alzheimer's Disease (AD) and normal controls to read aloud pronounceable letter strings that do not happen to be real words. These pseudowords were of two types: those that have orthographically similar "neighbors," and those that have no neighbors. The patients with AD were mildly impaired relative to the normal controls in reading pseudowords with neighbors, but were markedly impaired in reading pseudowords with no neighbors. The results are interpreted as favoring a model of reading in which words and pseudowords are normally read via the same lexical mechanism. An ancillary route involving the conscious application of spelling-to-sound rules is available only to cognitively intact readers.

journal_name

Brain Lang

journal_title

Brain and language

authors

Friedman RB,Ferguson S,Robinson S,Sunderland T

doi

10.1016/0093-934x(92)90109-r

subject

Has Abstract

pub_date

1992-10-01 00:00:00

pages

400-13

issue

3

eissn

0093-934X

issn

1090-2155

pii

0093-934X(92)90109-R

journal_volume

43

pub_type

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