Abstract:
:Polyunsaturated fatty acids (PUFAs) have been considered of great interest for human health due to their potential anti-inflammatory action that may protect from a number of chronic-degenerative diseases with an inflammatory pathogenesis. This review aimed to report the most updated evidence of both n-3 and n-6 PUFAs effect on cardiovascular disease, cancer, and depression in humans. Attention has been also paid to those studies exploring the effects of the ratio intake. Results from pooled analyses of human studies reported a general positive effect of n-3 PUFAs intake on all outcomes considered. In contrast, the role of n-6 PUFAs on human health needs to be better assessed in order to clearly identify which compound exerts beneficial/harmful effects. Only a limited number of clinical studies considered the n-3:n-6 PUFAs ratio, rather reporting contrasting results. A number of limitations when considering the ratio between these two families of PUFAs have risen.
journal_name
Int J Food Sci Nutrjournal_title
International journal of food sciences and nutritionauthors
Marventano S,Kolacz P,Castellano S,Galvano F,Buscemi S,Mistretta A,Grosso Gdoi
10.3109/09637486.2015.1077790subject
Has Abstractpub_date
2015-01-01 00:00:00pages
611-22issue
6eissn
0963-7486issn
1465-3478journal_volume
66pub_type
杂志文章,评审abstract::Evidence from animal and observational studies has supported the beneficial effects of beta-glucan intake on glycemic control, but intervention studies in hypercholesterolemic crowd have generated mixed results and have not been systematically examined. In the present study, we aimed to quantitatively evaluate the rel...
journal_title:International journal of food sciences and nutrition
pub_type: 杂志文章,meta分析,评审
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更新日期:2015-01-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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pub_type: 杂志文章,随机对照试验
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