Evaluation of antioxidant and anti-atherogenic properties of Glycyrrhiza glabra root using in vitro models.

Abstract:

:The aim of present study was to evaluate antioxidant property of Glycyrrhiza glabra root extracts using in vitro models. The dose-dependent aqueous and ethanolic extracts demonstrated the scavenging activity against nitric oxide (concentration that caused 50% inhibition of nitric oxide radicals [IC(50)]=72 and 62.1 microg/ml, respectively), superoxide (IC(50)=64.2 and 38.4 microg/ml, respectively), hydroxyl (IC(50)=81.9 and 63 microg/ml, respectively), DPPH (IC(50)=43.6 and 28.3 microg/ml, respectively) and ABTS(*+) (IC(50)=77.3 and 57.2 microg/ml, respectively) radicals. Further, both extracts showed strong reducing power and iron-chelating capacities. In the Fe(2+)/ascorbate system, both extracts were found to inhibit mitochondrial fraction lipid peroxidation. In copper-catalyzed human serum and low-density lipoprotein oxidation models, both extracts significantly (P<0.05) lengthened the lag phase along with a decline in the oxidation rate, conjugated dienes, lipid hydroperoxides and thiobarbituric acid reactive substance formation. In conclusion, ethanolic extract of G. glabra possess considerable antioxidant activity and protective effect against the human lipoprotein oxidative system.

journal_name

Int J Food Sci Nutr

authors

Visavadiya NP,Soni B,Dalwadi N

doi

10.1080/09637480902877998

subject

Has Abstract

pub_date

2009-01-01 00:00:00

pages

135-49

eissn

0963-7486

issn

1465-3478

pii

910630589

journal_volume

60 Suppl 2

pub_type

杂志文章
  • Quercetin is bioavailable from a single ingestion of grape juice.

    abstract::The in vivo bioactivity of polyphenols will depend on their bioavailability. Grape juice is an important source of dietary phenolics. This paper reports results that prove that quercetin (3,3',4',5,7-pentahydroxyflavone) is bioavailable after a single ingestion of red grape juice by healthy volunteers. Blood plasma sa...

    journal_title:International journal of food sciences and nutrition

    pub_type: 杂志文章

    doi:10.1080/09637480600858662

    authors: Dávalos A,Castilla P,Gómez-Cordovés C,Bartolomé B

    更新日期:2006-08-01 00:00:00

  • Effect of Amla fruit (Emblica officinalis Gaertn.) on blood glucose and lipid profile of normal subjects and type 2 diabetic patients.

    abstract::The present study evaluated the anti-hyperglycemic and lipid-lowering properties of Emblica officinalis Gaertn. fruit in normal and diabetic human volunteers. The results indicated a significant decrease (P <  0.05) in fasting and 2-h post-prandial blood glucose levels on the 21st day in both normal and diabetic subje...

    journal_title:International journal of food sciences and nutrition

    pub_type: 杂志文章

    doi:10.3109/09637486.2011.560565

    authors: Akhtar MS,Ramzan A,Ali A,Ahmad M

    更新日期:2011-09-01 00:00:00

  • Characterization and stability studies of bioactive compounds and food matrices as evidence in support of health claims.

    abstract::The characterization and stability evaluation of food and food constituents (chemical active ingredient/microorganism) for which nutrition or health claims want to be requested are essential for the success of an application to EFSA. This work reviews the requirements that must be fulfilled for a full characterization...

    journal_title:International journal of food sciences and nutrition

    pub_type: 杂志文章,评审

    doi:10.3109/09637486.2015.1042843

    authors: González-Ferrero C,Sáiz-Abajo MJ

    更新日期:2015-07-01 00:00:00

  • High insoluble fibre content increases in vitro starch digestibility in partially baked breads.

    abstract::Wheat breads prepared from frozen partially baked breads were characterized by their content of rapidly digestible starch (RDS) and slowly digestible starch (SDS) by the in vitro starch digestibility method developed by Englyst. Breads with different contents and types of fibre and breads prepared with different ferme...

    journal_title:International journal of food sciences and nutrition

    pub_type: 杂志文章

    doi:10.3109/09637486.2012.690025

    authors: Ronda F,Rivero P,Caballero PA,Quilez J

    更新日期:2012-12-01 00:00:00

  • Effect of polyoxyethylene sorbitan esters and sodium caseinate on physicochemical properties of palm-based functional lipid nanodispersions.

    abstract::The main objective of the present study was to investigate the effect of polyoxyethylene sorbitan esters and sodium caseinate on physicochemical properties of palm-based functional lipid nanodispersions prepared by the emulsification-evaporation technique. The results indicated that the average droplet size increased ...

    journal_title:International journal of food sciences and nutrition

    pub_type: 杂志文章

    doi:10.3109/09637481003591574

    authors: Cheong JN,Mirhosseini H,Tan CP

    更新日期:2010-06-01 00:00:00

  • Dietetic effects of oral intervention with mare's milk on the Severity Scoring of Atopic Dermatitis, on faecal microbiota and on immunological parameters in patients with atopic dermatitis.

    abstract::In a double-blind, placebo-controlled crossover trial, 23 patients consumed 250 ml mare's milk or placebo for 16 weeks. The aim was to examine the effects of mare's milk on the characteristics of atopic dermatitis (AD), on faecal microbiota and on clinical and immunological parameters. The intensity of AD was examined...

    journal_title:International journal of food sciences and nutrition

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1080/09637480802249082

    authors: Foekel C,Schubert R,Kaatz M,Schmidt I,Bauer A,Hipler UC,Vogelsang H,Rabe K,Jahreis G

    更新日期:2009-01-01 00:00:00

  • Effects of a plant-based fatty acid supplement and a powdered fruit, vegetable and berry juice concentrate on omega-3-indices and serum micronutrient concentrations in healthy subjects.

    abstract::The major aim of this controlled, randomised, open-labelled, parallel-grouped, clinical trial was to investigate whether supplementation with different dosages of omega-3 fatty acids (0.5 g/d and 1 g/d) from a plant-based fatty acid supplement affected omega-3-indices (O3I) in well-nourished, healthy people. In additi...

    journal_title:International journal of food sciences and nutrition

    pub_type: 杂志文章

    doi:10.1080/09637486.2020.1725960

    authors: Dams S,Holasek S,Tsiountsioura M,Edelsbrunner M,Dietz P,Koefeler H,Malliga DE,Gürbüz A,Meier-Allard N,Poncza B,Lackner S,Schwarzenberger E,Jansenberger Y,Lamprecht M

    更新日期:2020-09-01 00:00:00

  • Characteristic hydrolyzing of megalosaccharide by human salivary α-amylase and small intestinal enzymes, and its bioavailability in healthy subjects.

    abstract::The digestibility of Megalosaccharide® (newly developed carbohydrate comprising α-1,4-glucosaccharide) was investigated in vitro and in vivo. Isomaltosyl-megalosaccharide® (IMS) and nigerosyl-megalosaccharide® (NMS) contain 20% and 50% of the megalosaccharide fraction (degree of polymerization (DP) 10-35), respectivel...

    journal_title:International journal of food sciences and nutrition

    pub_type: 临床试验,杂志文章

    doi:10.3109/09637486.2014.908168

    authors: Nakamura S,Takami M,Tanabe K,Oku T

    更新日期:2014-09-01 00:00:00

  • Anaemia in relation to low bioavailability of dietary iron among school-aged children in the Aral Sea region, Kazakhstan.

    abstract::This study investigates anaemia related to the sufficiency of dietary iron intake of school-aged children in the Kzyl-Orda region of Kazakhstan. We conducted a cross-sectional study of 97 school-aged children living in Kzyl-Orda. Blood samples were collected for measuring haemoglobin. Dietary intake data were obtained...

    journal_title:International journal of food sciences and nutrition

    pub_type: 杂志文章

    doi:10.1080/09637480310001642466

    authors: Hashizume M,Shimoda T,Sasaki S,Kunii O,Caypil W,Dauletbaev D,Chiba M

    更新日期:2004-02-01 00:00:00

  • Comparison of mineral contents of mulberry (Morus spp.) fruits and their pekmez (boiled mulberry juice) samples.

    abstract::Mineral contents of four mulberry fruits and their pekmez samples growing particularly in the Malatya province in Turkey were determined by inductively coupled plasma atomic emission spectrometry. All samples contained high amounts of calcium, potassium, magnesium, sodium, phosphorus and sulphur. The highest mineral c...

    journal_title:International journal of food sciences and nutrition

    pub_type: 杂志文章

    doi:10.1080/09637480701695609

    authors: Akbulut M,Ozcan MM

    更新日期:2009-05-01 00:00:00

  • Partial substitution of sodium with potassium in white bread: feasibility and bioavailability.

    abstract::A high sodium intake, to which bread makes a major contribution, and a low potassium intake are believed to be important factors in the promotion of cardiovascular disease. Our aims was to determine to what extent salts of potassium could substitute sodium chloride and potassium-rich soya flour could replace wheat flo...

    journal_title:International journal of food sciences and nutrition

    pub_type: 杂志文章,随机对照试验

    doi:10.1080/09637480701782118

    authors: Braschi A,Gill L,Naismith DJ

    更新日期:2009-09-01 00:00:00

  • Regular consumption of Fiit-ns, a polyphenol extract from fruit and vegetables frequently consumed within the Mediterranean diet, improves metabolic ageing of obese volunteers: a randomized, double-blind, parallel trial.

    abstract::Epidemiological studies suggest that metabolic ageing process of overweight and obese populations is associated with an increased risk of developing non-communicable diseases (NCDs). Inflammation, hyper-glycaemia, dyslipidemia and oxidative stress have been associated with early stages of NCDs development whereas coho...

    journal_title:International journal of food sciences and nutrition

    pub_type: 杂志文章,随机对照试验

    doi:10.3109/09637486.2014.971229

    authors: Cases J,Romain C,Dallas C,Gerbi A,Cloarec M

    更新日期:2015-02-01 00:00:00

  • Probiotics and Covid-19.

    abstract::Coronavirus disease 2019 (COVID-19) has become pandemic very rapidly at the beginning of 2020. In the rush to possible therapeutic options, probiotics administration has been proposed mainly based on indirect observation. Some evidence of COVID-19 effects on intestinal microbiota dysbiosis has been shown and probiotic...

    journal_title:International journal of food sciences and nutrition

    pub_type: 杂志文章

    doi:10.1080/09637486.2020.1807475

    authors: Bottari B,Castellone V,Neviani E

    更新日期:2020-08-12 00:00:00

  • Transfer of (15)N from oral lactose-ureide to lysine in normal adults.

    abstract::The metabolic fate of salvaged urea-nitrogen was explored in normal adults who had consumed a diet that provided 36 g protein/day for 7 days. We hypothesised that the colonic microflora utilise nitrogen derived from urea salvage to synthesise lysine in functionally significant amounts for the host. Oral lactose-[(15)N...

    journal_title:International journal of food sciences and nutrition

    pub_type: 杂志文章

    doi:10.1080/09637480400015885

    authors: Jackson AA,Gibson NR,Bundy R,Hounslow A,Millward DJ,Wootton SA

    更新日期:2004-09-01 00:00:00

  • Critical differences between two low protein diet protocols in the programming of hypertension in the rat.

    abstract::Maternal nutrition has been identified as a factor determining fetal growth and risk of adult disease. In rats, the feeding of a low protein diet during pregnancy retards fetal growth and induces hypertension in the resulting offspring. Rat models of low protein feeding have been extensively used to study the mechanis...

    journal_title:International journal of food sciences and nutrition

    pub_type: 杂志文章

    doi:10.1080/096374800100859

    authors: Langley-Evans SC

    更新日期:2000-01-01 00:00:00

  • Vitamin E (α-tocopherol) consumption influences gut microbiota composition.

    abstract::This study evaluated if vitamin E consumption affects gut microbiota. Mice were grouped into control, low vitamin E (LV), and high vitamin E (HV). LV and HV were fed DL-α-tocopherol at 0.06 mg/20 g and 0.18 mg/20 g of body weight per day, respectively, for 34 days. Body weight of mice was measured before and after vit...

    journal_title:International journal of food sciences and nutrition

    pub_type: 杂志文章

    doi:10.1080/09637486.2019.1639637

    authors: Choi Y,Lee S,Kim S,Lee J,Ha J,Oh H,Lee Y,Kim Y,Yoon Y

    更新日期:2020-03-01 00:00:00

  • The relationship between dietary advanced glycation end products and indicators of diabetes severity in Mexicans and non-Hispanic whites: a pilot study.

    abstract::Diet is an important source of exogenous advanced glycation end products (AGEs). Dietary AGEs content depends on nutrient composition and on the way food is processed/cooked. The objective of our study was to compare AGEs intake of two different ethnic groups (Mexicans and non-Hispanic whites) with type 2 diabetes mel...

    journal_title:International journal of food sciences and nutrition

    pub_type: 杂志文章

    doi:10.3109/09637486.2012.704905

    authors: Luevano-Contreras C,Garay-Sevilla ME,Preciado-Puga M,Chapman-Novakofski KM

    更新日期:2013-02-01 00:00:00

  • Breakfast and mental health.

    abstract::The objective of the present investigation was to study the relationship between breakfast consumption and subjective reports of mental health and health-related behaviours in a general population sample (126 subjects aged between 20 and 79 years). Individuals who consumed a cereal breakfast each day were less depress...

    journal_title:International journal of food sciences and nutrition

    pub_type: 杂志文章

    doi:10.3109/09637489809089415

    authors: Smith AP

    更新日期:1998-09-01 00:00:00

  • Two meals with different carbohydrate, fat and protein contents render equivalent postprandial plasma levels of calprotectin, cortisol, triglycerides and zonulin.

    abstract::The aim was to compare postprandial plasma levels of calprotectin, cortisol, triglycerides and zonulin between a control breakfast and a moderately low-carbohydrate test breakfast, given randomly after 10-h fast. Blood samples were collected before and repeatedly after the meal. Plasma calprotectin, cortisol, triglyce...

    journal_title:International journal of food sciences and nutrition

    pub_type: 杂志文章

    doi:10.1080/09637486.2016.1202214

    authors: Ohlsson B,Darwiche G,Roth B,Höglund P

    更新日期:2016-11-01 00:00:00

  • In vitro catabolism of 3',4'-dihydroxycinnamic acid by human colonic microbiota.

    abstract::3',4'-Dihydroxycinnamic acid (aka caffeic acid) is a common dietary component found in a variety of plant-derived food products either in a free form or esterified as in chlorogenic acids such as 5-O-caffeoylquinic acid. The dihydroxycinnamate is produced principally by hydrolysis in the colon of 5-O-caffeoylquinic ac...

    journal_title:International journal of food sciences and nutrition

    pub_type: 杂志文章

    doi:10.1080/09637486.2020.1850650

    authors: Hasyima Omar M,González Barrio R,Pereira-Caro G,Almutairi TM,Crozier A

    更新日期:2020-11-25 00:00:00

  • Gluten-free diet or alternative therapy: a survey on what parents of celiac children want.

    abstract:OBJECTIVES:Celiac disease (CD) is treated by life-long gluten-free diet (GFD). Novel therapies are under development. Willingness of CD children's parents to alternative therapies and GFD impact were evaluated. METHODS:Parents of celiac children on GFD were investigated on need and preference for novel CD therapies, c...

    journal_title:International journal of food sciences and nutrition

    pub_type: 杂志文章

    doi:10.3109/09637486.2015.1064872

    authors: Norsa L,Tomba C,Agostoni C,Branchi F,Bardella MT,Roncoroni L,Conte D,Elli L

    更新日期:2015-01-01 00:00:00

  • The edible mushroom Laetiporus sulphureus as potential source of natural antioxidants.

    abstract::Hot water extract (LN), partially purified polysaccharides (LP) and hot alkali extracted polysaccharides (LNa) obtained from fruiting bodies of the wild basidiomycete Laetiporus sulphureus were examined for their antioxidant activities. LNa was the most active antioxidant, as shown by the median effective concentratio...

    journal_title:International journal of food sciences and nutrition

    pub_type: 杂志文章

    doi:10.3109/09637486.2012.759190

    authors: Klaus A,Kozarski M,Niksic M,Jakovljevic D,Todorovic N,Stefanoska I,Van Griensven LJ

    更新日期:2013-08-01 00:00:00

  • Dietary total antioxidant capacity and obesity in children and adolescents.

    abstract:BACKGROUND:Dietary antioxidant intake has been suggested to protect against oxidative damage and related clinical complications. The aim of the present study was to assess the potential relationships between the dietary total antioxidant capacity (TAC) and obesity-related features in children and adolescents. MATERIAL...

    journal_title:International journal of food sciences and nutrition

    pub_type: 杂志文章

    doi:10.3109/09637481003757860

    authors: Puchau B,Ochoa MC,Zulet MA,Marti A,Martínez JA,Members G

    更新日期:2010-11-01 00:00:00

  • Nutritive value and chemical composition of prickly pear seeds (Opuntia ficus indica L.) growing in Turkey.

    abstract::The proximate composition and physico-chemical properties (moisture, crude lipid, crude protein, ash, and crude fiber, peroxide value, saponification value, acidity, relative density and refractive index) of prickly pear seed and corresponding oil were determined. The mineral contents (Ca, Cu, Fe, K, Mg, Na, P, Mn and...

    journal_title:International journal of food sciences and nutrition

    pub_type: 杂志文章

    doi:10.3109/09637486.2011.552569

    authors: Özcan MM,Al Juhaimi FY

    更新日期:2011-08-01 00:00:00

  • Influence of debittered, defatted fenugreek seed powder and flaxseed powder on the rheological characteristics of dough and quality of cookies.

    abstract::A functional ingredient mix (FIM) comprising debittered and defatted fenugreek seed powder (70%) and flaxseed powder (30%) was used in cookies. Ash, fat and protein, dough development time, resistance to extension and peak viscosity values increased as the level of FIM increased from 10 to 30% in the blend. Beyond 20%...

    journal_title:International journal of food sciences and nutrition

    pub_type: 杂志文章

    doi:10.3109/09637486.2010.536145

    authors: Metwal N,Jyotsna R,Jeyarani T,Venkateswara Rao G

    更新日期:2011-06-01 00:00:00

  • Influence of low versus moderate glycemic index of diet on substrate oxidation and energy expenditure during incremental exercise in endurance athletes: a randomized counterbalanced cross-over trial.

    abstract::The study was aimed at assessing the influence of 3-week low glycemic index (LGI) versus moderate glycemic index (MGI) diet on substrate oxidation during incremental exercise. 17 runners completed two 3-week trials of either LGI or MGI diet in a randomised counterbalanced manner. Before and after each trial the increm...

    journal_title:International journal of food sciences and nutrition

    pub_type: 杂志文章,随机对照试验

    doi:10.1080/09637486.2017.1411891

    authors: Durkalec-Michalski K,Zawieja EE,Zawieja BE,Podgórski T,Jurkowska D,Jeszka J

    更新日期:2018-09-01 00:00:00

  • Effects of preparation procedures on ascorbic acid retention in pickled hot peppers.

    abstract::The effect of preparation procedures (with and without sugar and chickpea) on ascorbic acid in pickled (acidification with vinegar) green hot peppers during pickling and the storage period (8 weeks) was studied. Ascorbic acid values in fresh pepper rapidly decreased after pickled processing (first 3 weeks) and then di...

    journal_title:International journal of food sciences and nutrition

    pub_type: 杂志文章

    doi:10.1080/09637480120092116

    authors: Yalim S,Ozdemir Y

    更新日期:2003-07-01 00:00:00

  • Comparison between single-cell cultures and tissue cultures as model systems for evaluating the modulation of gene expression by food bioactives.

    abstract::In this study, we sought the use of cultured human abdominal aortic aneurysm (AAA) tissue to investigate the transcriptional effects of some bioactives, whose role in the prevention of atherosclerotic plaque development through the regulation of gene expression has been hypothesized. After supplementation with n - 3 p...

    journal_title:International journal of food sciences and nutrition

    pub_type: 杂志文章

    doi:10.3109/09637486.2012.728200

    authors: Boschetti E,Bacon JR,Meyer F,Tugnoli V,Bordoni A,Kroon PA

    更新日期:2013-03-01 00:00:00

  • Snack bars with high soy protein and isoflavone content for use in diets to control dyslipidaemia.

    abstract::The objective was to develop a cereal bar product rich in isoflavones and soy protein to be used in diets for controlling dyslipidaemia. A soy snack bar with 39.88 g/100 g dietary fibre, 34.25 g/100 g protein, 100.39 mg/100 g isoflavones and 245.47 kcal/100 g was produced. The shelf life of the product was tested over...

    journal_title:International journal of food sciences and nutrition

    pub_type: 临床试验,杂志文章

    doi:10.3109/09637486.2011.596148

    authors: Lobato LP,Iakmiu Camargo Pereira AE,Lazaretti MM,Barbosa DS,Carreira CM,Mandarino JM,Grossmann MV

    更新日期:2012-02-01 00:00:00

  • Physical and chemical analysis of Passiflora seeds and seed oil from China.

    abstract::The physical and chemical properties of seeds and seed oil from 'Tainung No. 1' passion fruit in China have been analyzed in order to evaluate their nutritional value. Proximate analysis shows that the seeds have a high amount of protein (10.8 +/- 0.60%) and are rich in oil (23.40 +/- 2.50%). The seeds are found to be...

    journal_title:International journal of food sciences and nutrition

    pub_type: 杂志文章

    doi:10.1080/09637480801931128

    authors: Liu S,Yang F,Li J,Zhang C,Ji H,Hong P

    更新日期:2008-11-01 00:00:00