Characterization and stability studies of bioactive compounds and food matrices as evidence in support of health claims.

Abstract:

:The characterization and stability evaluation of food and food constituents (chemical active ingredient/microorganism) for which nutrition or health claims want to be requested are essential for the success of an application to EFSA. This work reviews the requirements that must be fulfilled for a full characterization of the active substance, comprising origin, elaboration, or extraction method, and chemical/microbiological composition, using validated analytical methods. The review focuses not only on establishing the specifications of the final active ingredient or food but also on ensuring homogeneity between batches. In addition, the article discusses the methodologies and conditions of the stability studies that need to be performed on food and food constituents to verify that the relevant compounds--chemical and microbiological active ingredients--will get to the consumer in the intended state and concentration to accomplish the claimed health effect over shelf life.

journal_name

Int J Food Sci Nutr

authors

González-Ferrero C,Sáiz-Abajo MJ

doi

10.3109/09637486.2015.1042843

subject

Has Abstract

pub_date

2015-07-01 00:00:00

pages

S4-S12

eissn

0963-7486

issn

1465-3478

pii

10.3109/09637486.2015.1042843

journal_volume

66 Suppl 1

pub_type

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