Dietetic effects of oral intervention with mare's milk on the Severity Scoring of Atopic Dermatitis, on faecal microbiota and on immunological parameters in patients with atopic dermatitis.

Abstract:

:In a double-blind, placebo-controlled crossover trial, 23 patients consumed 250 ml mare's milk or placebo for 16 weeks. The aim was to examine the effects of mare's milk on the characteristics of atopic dermatitis (AD), on faecal microbiota and on clinical and immunological parameters. The intensity of AD was examined using the Severity Scoring of Atopic Dermatitis (SCORAD) index. During the mare's milk period, the mean SCORAD value of patients (n=23; 17 females, 6 males) decreased from 30.1 to 25.3 after 12 weeks (P<0.05) and to 26.7 after 16 weeks (P<0.1). In a subgroup (n=7) the SCORAD index and especially the pruritus decreased by 30% through the mare's milk period (P<0.01). In this subgroup, the faecal bifidobacteria increased during the mare's milk period from 4.6% to 11.9% of eubacteria (P<0.05). The immunological parameters, except C-reactive protein, were unchanged.

journal_name

Int J Food Sci Nutr

authors

Foekel C,Schubert R,Kaatz M,Schmidt I,Bauer A,Hipler UC,Vogelsang H,Rabe K,Jahreis G

doi

10.1080/09637480802249082

subject

Has Abstract

pub_date

2009-01-01 00:00:00

pages

41-52

eissn

0963-7486

issn

1465-3478

pii

911592396

journal_volume

60 Suppl 7

pub_type

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