Abstract:
:In a double-blind, placebo-controlled crossover trial, 23 patients consumed 250 ml mare's milk or placebo for 16 weeks. The aim was to examine the effects of mare's milk on the characteristics of atopic dermatitis (AD), on faecal microbiota and on clinical and immunological parameters. The intensity of AD was examined using the Severity Scoring of Atopic Dermatitis (SCORAD) index. During the mare's milk period, the mean SCORAD value of patients (n=23; 17 females, 6 males) decreased from 30.1 to 25.3 after 12 weeks (P<0.05) and to 26.7 after 16 weeks (P<0.1). In a subgroup (n=7) the SCORAD index and especially the pruritus decreased by 30% through the mare's milk period (P<0.01). In this subgroup, the faecal bifidobacteria increased during the mare's milk period from 4.6% to 11.9% of eubacteria (P<0.05). The immunological parameters, except C-reactive protein, were unchanged.
journal_name
Int J Food Sci Nutrjournal_title
International journal of food sciences and nutritionauthors
Foekel C,Schubert R,Kaatz M,Schmidt I,Bauer A,Hipler UC,Vogelsang H,Rabe K,Jahreis Gdoi
10.1080/09637480802249082subject
Has Abstractpub_date
2009-01-01 00:00:00pages
41-52eissn
0963-7486issn
1465-3478pii
911592396journal_volume
60 Suppl 7pub_type
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