Abstract:
OBJECTIVES:Celiac disease (CD) is treated by life-long gluten-free diet (GFD). Novel therapies are under development. Willingness of CD children's parents to alternative therapies and GFD impact were evaluated. METHODS:Parents of celiac children on GFD were investigated on need and preference for novel CD therapies, children's enrolment in trials, compliance to and personal judgment on GFD, health status (HS) and quality of life (QoL). RESULTS:About 59.5% surveyed parents expressed the need for alternative therapies with a preference for vaccine-based strategy (39.9%). About 37.7% would accept enrollment in an ad hoc trial, 20.3% would agree to endoscopy during the trial. GFD compliance was 97.4% and well accepted by 93.8%. HS and QoL significantly improved during GFD (p < 0.001). CONCLUSIONS:The introduction of novel therapies for CD is desirable for over half of parents, with preference for vaccines. Parents frown upon enrolment in new clinical trials and the subsequent need for additional endoscopy.
journal_name
Int J Food Sci Nutrjournal_title
International journal of food sciences and nutritionauthors
Norsa L,Tomba C,Agostoni C,Branchi F,Bardella MT,Roncoroni L,Conte D,Elli Ldoi
10.3109/09637486.2015.1064872subject
Has Abstractpub_date
2015-01-01 00:00:00pages
590-4issue
5eissn
0963-7486issn
1465-3478journal_volume
66pub_type
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