Vitamin E (α-tocopherol) consumption influences gut microbiota composition.

Abstract:

:This study evaluated if vitamin E consumption affects gut microbiota. Mice were grouped into control, low vitamin E (LV), and high vitamin E (HV). LV and HV were fed DL-α-tocopherol at 0.06 mg/20 g and 0.18 mg/20 g of body weight per day, respectively, for 34 days. Body weight of mice was measured before and after vitamin E treatment. Animals were sacrificed, liver, spleen, small intestine and large intestine collected, and weight and length were measured. Composition of gut microbiota was determined by microbiome analysis. Spleen weight index of LV was the highest. However, liver weight indices and intestinal lengths were not different. Body weights of LV group were higher than those of control. Ratio of Firmicutes to Bacteroidetes was different in LV compared to control and HV. These results indicate that low-level consumption of vitamin E increases spleen and body weight, and changes gut microbiota.

journal_name

Int J Food Sci Nutr

authors

Choi Y,Lee S,Kim S,Lee J,Ha J,Oh H,Lee Y,Kim Y,Yoon Y

doi

10.1080/09637486.2019.1639637

subject

Has Abstract

pub_date

2020-03-01 00:00:00

pages

221-225

issue

2

eissn

0963-7486

issn

1465-3478

journal_volume

71

pub_type

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