Abstract:
:This study evaluated if vitamin E consumption affects gut microbiota. Mice were grouped into control, low vitamin E (LV), and high vitamin E (HV). LV and HV were fed DL-α-tocopherol at 0.06 mg/20 g and 0.18 mg/20 g of body weight per day, respectively, for 34 days. Body weight of mice was measured before and after vitamin E treatment. Animals were sacrificed, liver, spleen, small intestine and large intestine collected, and weight and length were measured. Composition of gut microbiota was determined by microbiome analysis. Spleen weight index of LV was the highest. However, liver weight indices and intestinal lengths were not different. Body weights of LV group were higher than those of control. Ratio of Firmicutes to Bacteroidetes was different in LV compared to control and HV. These results indicate that low-level consumption of vitamin E increases spleen and body weight, and changes gut microbiota.
journal_name
Int J Food Sci Nutrjournal_title
International journal of food sciences and nutritionauthors
Choi Y,Lee S,Kim S,Lee J,Ha J,Oh H,Lee Y,Kim Y,Yoon Ydoi
10.1080/09637486.2019.1639637subject
Has Abstractpub_date
2020-03-01 00:00:00pages
221-225issue
2eissn
0963-7486issn
1465-3478journal_volume
71pub_type
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