Abstract：
BACKGROUND:Surgical site infection (SSI) after neurosurgery has potentially devastating consequences. METHODS:A prospective cohort study was conducted over a period of 24 months in a university center. All adult patients undergoing neurosurgical procedures, with exception of open skull fractures, were included. Multivariate logistic regression analysis was used to identify independent risk factors. RESULTS:We included 949 patients. Among them, 43 were diagnosed with SSI (4.5%). A significant reduction in postneurosurgical SSI from 5.8% in 2009 to 3.0% in 2010 (P = .04) was observed. During that period, an active surveillance with regular feedback was established. The most common microorganisms isolated from SSI were Staphylococcus aureus (23%), Enterobacteriaceae (21%), and Propionibacterium acnes (12%). We identified the following independent risk factors for SSI postcranial surgery: intensive care unit (ICU) length of stay ≥7 days (odds ratio [OR] = 6.1; 95% confidence interval [CI], 1.7-21.7), duration of drainage ≥3 days (OR = 3.3; 95% CI, 1.1-11), and cerebrospinal fluid leakage (OR = 5.6; 95% CI, 1.1-30). For SSIs postspinal surgery, we identified the following: ICU length of stay ≥7 days (OR = 7.2; 95% CI, 1.6-32.1), coinfection (OR = 9.9; 95% CI, 2.2-43.4), and duration of drainage ≥3 days (OR = 5.7; 95% CI, 1.5-22). CONCLUSION:Active surveillance with regular feedback proved effective in reducing SSI rates. The postoperative period is associated with overlooked risk factors for neurosurgical SSI. Infection control measures targeting this period are therefore promising.
journal_name
Am J Infect Controljournal_title
American journal of infection controlauthors
Cassir N,De La Rosa S,Melot A,Touta A,Troude L,Loundou A,Richet H,Roche PHdoi
10.1016/j.ajic.2015.07.005subject
Has Abstractpub_date
2015-12-01 00:00:00pages
1288-91issue
12eissn
0196-6553issn
1527-3296pii
S0196-6553(15)00756-7journal_volume
43pub_type
杂志文章abstract：BACKGROUND:Animals could be reservoirs of extended-spectrum β-lactamases (ESBL) strains, but epidemiologic data on ESBL-producing bacteria in healthy pets are missing. We determined the prevalence of ESBL-producing Enterobacteriaceae in pets living in nursing homes and in households to investigate the potential role of...
journal_title：American journal of infection control
pub_type： 杂志文章
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更新日期：2018-07-01 00:00:00
abstract：BACKGROUND:Little is known about the direct economic burden associated with health care-associated infection (HAI) in patients undergoing colorectal cancer surgery in China. This study aims to fill this knowledge gap. METHODS:This study was a prospective monitoring case-control study. The direct economic burden was pr...
journal_title：American journal of infection control
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更新日期：2018-01-01 00:00:00
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journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2018.04.232
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abstract：:Human factors design interventions have been suggested to mitigate infection risk in health care. Among such solutions, many are easily identified and theoretically simple and quick to realize. These are called low-hanging fruit. We present a case of infection risk associated with syringe manipulation that could easil...
journal_title：American journal of infection control
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abstract：:Manual counting is considered the gold standard for device day recording by the National Health Safety Network. We describe the development of a process for an electronic count of central line days across our ten-hospital health care system. Our validation process identified discordance between the electronic count an...
journal_title：American journal of infection control
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journal_title：American journal of infection control
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doi：10.1016/j.ajic.2008.05.011
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pub_type： 杂志文章,随机对照试验
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更新日期：2014-02-01 00:00:00
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journal_title：American journal of infection control
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abstract：:The failure of the 1982-1983 influenza vaccine to protect elderly NHCU residents from clinical infection with influenza A/Philippines/2/82 resulted primarily from antigenic drift of the epidemic strain, inasmuch as the attack rates in the vaccinated and nonvaccinated patients were not significantly different. This exp...
journal_title：American journal of infection control
pub_type： 杂志文章
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更新日期：1984-12-01 00:00:00
abstract：BACKGROUND:The incidence of postoperative surgical site infections (SSIs) is difficult to estimate because of the current trend of early discharge after surgery. Both operation-related and host factors should be taken into consideration in the prevention of SSIs. We wanted to determine the actual incidence of SSIs and ...
journal_title：American journal of infection control
pub_type： 临床试验,杂志文章
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更新日期：1997-10-01 00:00:00
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journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2008.01.013
更新日期：2009-03-01 00:00:00
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journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2011.07.001
更新日期：2012-06-01 00:00:00
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journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/s0196-6553(98)80035-7
更新日期：1998-04-01 00:00:00
abstract：:Health care workers (HCWs) are susceptible to hospital acquired varicella zoster virus (VZV). We evaluated seroprevalence and predictive value of a history of varicella disease (VD) with VZV serology in HCWs in northern Israel. A total of 200 HCWs were enrolled. A high rate of seropositivity for VZV-IgG was found: 98....
journal_title：American journal of infection control
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doi：10.1016/j.ajic.2007.06.004
更新日期：2008-08-01 00:00:00
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journal_title：American journal of infection control
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journal_title：American journal of infection control
pub_type： 杂志文章
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更新日期：2007-02-01 00:00:00
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journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2010.09.008
更新日期：2011-06-01 00:00:00
abstract：:Central line-associated bloodstream infection (CLABSI) event data reported to the National Healthcare Safety Network from 2014, the first year of required use of the mucosal barrier injury laboratory-confirmed bloodstream infection (MBI-LCBI) definition, were analyzed to assess the impact of removing MBI-LCBI events f...
journal_title：American journal of infection control
pub_type： 杂志文章
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更新日期：2017-03-01 00:00:00
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journal_title：American journal of infection control
pub_type： 杂志文章
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更新日期：2021-02-01 00:00:00
abstract：:We monitored hand surface coverage technique in health care workers in a tertiary care hospital using a 5-item hand hygiene assessment tool based on World Health Organization guidelines. Overall hand hygiene compliance was 86.7% (4,300/4,960). Appropriate hand surface coverage was observed in only 7.9% (182/2,297) of ...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2013.12.014
更新日期：2014-05-01 00:00:00
abstract：BACKGROUND:Limited information is available on the financial impact of central venous catheter-associated bloodstream infection (BSI) in Argentina. To calculate the cost of BSIs in the intensive care department (ICU), a 5-year prospective nested case-control study was undertaken at 3 hospitals in Argentina. METHODS:We...
journal_title：American journal of infection control
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ajic.2003.03.002
更新日期：2003-12-01 00:00:00
