Abstract：
BACKGROUND:This study evaluated whether a multi-ingredient surfactant colloidal silver technology was noninferior to a 4% chlorhexidine gluconate (CHG) antiseptic on immediate and persistent antimicrobial activity. METHODS:The inguinal regions of 81 healthy adults were demarcated into 4 quadrants, and 3 were used for testing each product at baseline, 10 minutes, and 6 hours postapplication. The log of the number of colony forming units was obtained using a cylinder sampling technique. The 95% confidence interval of the test product to the control product with a margin of 0.65 was established as the upper limit of noninferiority. RESULTS:A total of 81 individuals were enrolled. The colloidal silver product was found to be noninferior to 4% CHG at both 10 minutes and 6 hours postapplication. CONCLUSIONS:The colloidal silver-based product was noninferior to the 4% CHG product at 10 minutes and 6 hours postapplication.
journal_name
Am J Infect Controljournal_title
American journal of infection controlauthors
Paulson DS,Topp R,Boykin RE,Schultz G,Yang Qdoi
10.1016/j.ajic.2018.04.232subject
Has Abstractpub_date
2018-11-01 00:00:00pages
1262-1265issue
11eissn
0196-6553issn
1527-3296pii
S0196-6553(18)30572-8journal_volume
46pub_type
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journal_title：American journal of infection control
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journal_title：American journal of infection control
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