当前位置： SCI文献检索 > AMERICAN JOURNAL OF INFECTION CONTROL期刊下所有文献 > Mycobacterium tuberculosis transmission rates in a sanatorium: implications for new preventive guidelines.

Mycobacterium tuberculosis transmission rates in a sanatorium: implications for new preventive guidelines.

Abstract：

BACKGROUND:In 1990, the Centers for Disease Control and Prevention recommended substituting dust-mist particulate respirators for simple isolation masks in acid-fast bacillus isolation rooms, reasoning that air leaks around the simple masks could result in a higher rate of purified protein derivative skin-test conversion. In 1993, a Centers for Disease Control and Prevention draft guideline proposed that high-efficiency particulate air filter respirators be used instead of dust-mist particulate respirators. Epidemiologic data were not available to assess the importance of these changes or their cost-effectiveness. METHODS:The University of Virginia was affiliated with a tuberculosis hospital from 1979 until 1987. We surveyed physicians who had served as residents in internal medicine during this period regarding purified protein derivative skin-test history. duration of work at the tuberculosis sanatorium, and any history of unprotected exposures to patients with active pulmonary or laryngeal tuberculosis. Patients with active tuberculosis at the sanatorium were isolated in negative-pressure rooms with UV lights. Physicians wore simple isolation masks in these rooms. RESULTS:Responses were received from 83 former resident physicians. Fifty-two physicians had worked on the tuberculosis wards for a total of 420 weeks, with no subsequent skin-test conversions (95% CI 0 to 1 conversion/8 physician-years). CONCLUSIONS:These data document a low risk of occupational transmission of Mycobacterium tuberculosis to physicians who wear simple isolation masks in negative-pressure ventilation rooms with UV lights. This low rate predicts that the additional protective efficacy and cost-effectiveness of the more expensive high-efficiency particulate air filter respirators and the respiratory protection program will be low.

journal_name

Am J Infect Control

journal_title

American journal of infection control

authors

Jernigan JA,Adal KA,Anglim AM,Byers KE,Farr BM

doi

10.1016/0196-6553(94)90030-2

subject

Has Abstract

pub_date

1994-12-01 00:00:00

pages

329-33

issue

eissn

0196-6553

issn

1527-3296

pii

0196-6553(94)90030-2

journal_volume

pub_type

杂志文章

在线工具

Mycobacterium tuberculosis transmission rates in a sanatorium: implications for new preventive guidelines.