当前位置： SCI文献检索 > AMERICAN JOURNAL OF INFECTION CONTROL期刊下所有文献 > The effectiveness of sodium dichloroisocyanurate treatments against Clostridium difficile spores contaminating stainless steel.

The effectiveness of sodium dichloroisocyanurate treatments against Clostridium difficile spores contaminating stainless steel.

Abstract：

BACKGROUND:Clostridium difficile is a major cause of hospital-associated infective diarrhea, and its spore form can persist for months in the hospital environment. Chlorine-based cleaning agents are recommended for eliminating this reservoir of potential infection. OBJECTIVES:To investigate the individual contributions of active chlorine, detergent and mechanical action on decontamination of a C difficile contaminated surface. METHODS:C difficile spores in test soil were dried onto stainless steel strips and exposed to sodium dichloroisocyanurate (NaDCC) or NaDCC combined with detergent (NaDCC+) or exposed to these cleaning formulations combined with wiping and/or detergent precleaning. After set contact times, remaining viable spores from the strips were recovered and enumerated by vortexing with glass beads, followed by membrane filtration. RESULTS:Compared with NaDCC, the inclusion of detergent in the NaDCC+ formulation did not improve the effectiveness of decontamination in any exposure-only treatment at concentrations tested (P > .05). Combining wiping with exposure to the cleaning formulations improved decontamination effectiveness with further reductions in spore counts of 1.66- and 2.19-log(10) colony-forming units at 2 and 20 minutes, respectively, using NaDCC, and of 2.46 and 2.56 log(10) colony-forming units at 2 and 20 minutes, respectively, using NaDCC+. Precleaning the strips by wiping with detergent before exposure to NaDCC was more effective than wiping with NaDCC or NaDCC+ at 10 and 20 minutes contact times. Wiping with NaDCC+ was more effective than NaDCC only at a 2-minute contact time. Wiping with detergent followed by subsequent wiping with NaDCC (1,000 ppm) was the most effective treatment tested with a 4.00-log(10) reduction observed. CONCLUSION:Rigorous precleaning with detergent and the associated physical removal of spores through the mechanical action associated with wiping are important factors in achieving effective decontamination of surfaces when using chlorine-based agents.

journal_name

Am J Infect Control

journal_title

American journal of infection control

authors

Ungurs M,Wand M,Vassey M,O'Brien S,Dixon D,Walker J,Sutton JM

doi

10.1016/j.ajic.2010.07.015

subject

Has Abstract

pub_date

2011-04-01 00:00:00

pages

199-205

issue

eissn

0196-6553

issn

1527-3296

pii

S0196-6553(10)00902-8

journal_volume

pub_type

杂志文章

在线工具

The effectiveness of sodium dichloroisocyanurate treatments against Clostridium difficile spores contaminating stainless steel.