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The changing landscape of respiratory syncytial virus.

Abstract：

:Recognition of the acute and chronic burden of respiratory syncytial virus (RSV) lower respiratory tract infections (LRTI) sparked a wave of initiatives to develop preventive and therapeutic products against the pathogen in recent years. RSV is a leading cause of hospitalization in infants in industrialized and developing countries, has been causally linked to recurrent wheezing during childhood, associated with pediatric asthma, and is an important cause of mortality in the first months of life in the developing world. Significant changes in the epidemiology, clinical manifestations, and severe consequences of LRTI may emerge in the next decade with the advent of novel preventive strategies against RSV. This manuscript outlines some of these changes and discusses potential scenarios based on the current literature and experiences with other pathogens.

journal_name

Vaccine

journal_title

Vaccine

authors

Polack FP

doi

10.1016/j.vaccine.2015.06.119

subject

Has Abstract

pub_date

2015-11-25 00:00:00

pages

6473-8

issue

47

eissn

0264-410X

issn

1873-2518

pii

S0264-410X(15)01072-5

journal_volume

33

pub_type

杂志文章,评审

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