Abstract：
:Addressing inequities in immunisation must be the main priority for the Decade of Vaccines. Children who remain unreached are those who need vaccination - and other health services - most. Reaching these children and other underserved target groups will require a reorientation of current approaches and resource allocation. At the country level, evidence-based and context-specific strategies must be developed to promote equity in ways that strengthen the system that facilitates vaccination, are sustainable and extend benefits across the life cycle. At the global level, more attention must go on ensuring sustainable and affordable supply for low- and middle-income countries to vaccine products that are appropriate for the contexts where needs are greatest. Finally, data must be disaggregated and used at all levels to monitor and guide progress to reach the unreached.
journal_name
Vaccinejournal_title
Vaccineauthors
Brearley L,Eggers R,Steinglass R,Vandelaer Jdoi
10.1016/j.vaccine.2012.11.088subject
Has Abstractpub_date
2013-04-18 00:00:00pages
B103-7eissn
0264-410Xissn
1873-2518pii
S0264-410X(12)01739-2journal_volume
31 Suppl 2pub_type
杂志文章,评审相关文献
VACCINE文献大全abstract：:In the present study, cross-protection to bovine herpesvirus type 5 (BHV-5) induced by bovine herpesvirus type 1 (BHV-1) vaccination was examined following inoculation of rabbits and calves with a glycoprotein E (gE)-negative BHV-1 vaccine and subsequent challenge with BHV-5. Rabbits (n=5) and calves (n=8) were vaccin...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2006.01.024
更新日期：2006-04-12 00:00:00
abstract：:An attenuated chikungunya (CHIK) virus clone was developed for production of a live vaccine for human use. CHIK strain 15561 was subjected to 18 plaque-to-plaque passages in MRC-5 cultures before CHIK 181/clone 25 was selected as vaccine seed based on homogeneous small plaque size, suckling mouse avirulence, reduced m...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/0264-410x(86)90003-4
更新日期：1986-09-01 00:00:00
abstract：:We investigated the influence of the site of administration of DNA vaccine on the induced immune response. DNA vaccines were administered by electroporation at three different sites: tibial cranial muscle, abdominal skin and ear pinna. Aiming to draw general conclusions about DNA vaccine delivery, we successively used...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2015.05.005
更新日期：2015-06-22 00:00:00
abstract：:We have demonstrated that the fibrinogen-albumin-IgG receptor of group C streptococci (FAI) targets B-cells in vivo. We exploited the targeting properties of FAI to improve the immune responses stimulated by soluble antigens administered by the mucosal route. Enhanced systemic and mucosal immune responses were observe...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2004.08.045
更新日期：2005-02-03 00:00:00
abstract：:Systemic infection by Salmonella typhimurium requires coordinated expression of virulence genes found primarily in Salmonella Pathogenecity Islands (SPIs). We have previously reported that the intracellular signal that induces these virulence genes is a stringent signal molecule, ppGpp [Song et al. J Biol Chem 2003;27...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2005.11.031
更新日期：2006-03-15 00:00:00
abstract：:In Japan, trivalent inactivated influenza vaccine is the only approved influenza vaccine. It is typically administrated by hypodermic injection, and children under 13 years of age are recommended to be vaccinated two times during each winter season. Live-attenuated influenza vaccine (LAIV) is administered by a thimero...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2014.07.002
更新日期：2014-09-03 00:00:00
abstract：:Cysteine peptidases (CPs) have been implicated in various processes central to the pathogenicity of Leishmania parasites, and are thought to be key factors in the host-parasite interaction. In order to fully evaluate the potential of the CPs as vaccine candidates, studies in natural host species are required. In the s...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2005.12.039
更新日期：2006-03-24 00:00:00
abstract：BACKGROUND:Worldwide coverage of hepatitis B (HB) vaccination is increasing. This should be considered when determining the best strategy for catch-up HB vaccination in migrant children, who rarely have written proof of past immunizations. This study aimed to estimate HB vaccine protection, chronic HB prevalence and to...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2018.06.010
更新日期：2018-07-16 00:00:00
abstract：:The distribution of alpha-casein, bovine serum albumin (BSA), myoglobin and recombinant protective antigen (rPA) in mono-valent and combination vaccines containing aluminum hydroxide adjuvant was studied by fluorescence microscopy and flow cytometry. Green and red fluorescent probes were conjugated to the antigens. Ad...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2003.10.040
更新日期：2004-05-07 00:00:00
abstract：BACKGROUND:Zika virus vaccine development is underway. We examined interest in receiving a Zika virus vaccine (after one becomes commercially available) among students at a large public university in Northern Virginia. METHODS:An online survey of Zika virus-related knowledge, attitudes, and interest in receiving a Zik...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2016.12.050
更新日期：2017-02-07 00:00:00
abstract：:In the face of an almost unprecedented threat of a global pandemic of influenza it is imperative that stockpiling of appropriate drugs and devices begin now. One vital device is an appropriate syringe for delivering vaccine. With the potential for millions to be infected and the vaccine supply severely stretched it is...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2006.02.056
更新日期：2006-05-29 00:00:00
abstract：:After a single injection of Typhim Vi (typhoid Vi polysaccharide vaccine), serum antibody concentrations were monitored for 3 years in 37 adults who resided where typhoid fever was not endemic. Anti-Vi antibody concentrations declined progressively during the study, to levels that support the current US recommendation...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2009.11.051
更新日期：2010-02-10 00:00:00
abstract：:Purified Vero cell culture rabies vaccine "Abhayrab" manufactured by Human Biologicals Institute, Ooty, India was subjected for immunogenicity studies. Pre-exposure study was undertaken on 60 healthy volunteers (Group I) with vaccination on days 0, 7 and 21. A group of 75 patients of category II (Group II), 67 of cate...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2004.08.001
更新日期：2005-01-04 00:00:00
abstract：:An effective virus-like particle (VLP) based prophylactic vaccine designed to protect against persistent infection with human papillomavirus (HPV) types 16 and 18 and subsequent lesion development will need to induce a strong humoral and cellular immune response capable of providing long-term protection. Our objective...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2006.06.005
更新日期：2006-08-14 00:00:00
abstract：:The most common preventative measure against mumps is vaccination with mumps vaccine. In most parts of the world, mumps vaccine is routinely delivered through live attenuated Measles-Mumps-Rubella (MMR) vaccine. In Japan, receiving mumps vaccine is voluntary and vaccine uptake rate is less than 30%. The introduction o...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2014.05.020
更新日期：2014-07-16 00:00:00
abstract：:The 9-valent Human Papillomavirus (HPV) vaccine, 9vHPV, was licensed in the U.S. in December, 2014. We assessed healthcare provider (HCP) awareness of the newly approved vaccine and identified questions HCPs have about the vaccine. As part of a larger study, we used semi-structured interviews to ask 22 pediatric HCPs ...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2016.01.050
更新日期：2016-03-08 00:00:00
abstract：:Cytology-based screening has reduced cervical cancer mortality in countries able to implement, sustain and financially support organized programs that achieve broad coverage. These ongoing secondary prevention efforts considerably complicate the question of whether vaccination against human papillomavirus (HPV) types ...
journal_title：Vaccine
pub_type： 杂志文章,评审
doi：10.1016/j.vaccine.2008.06.009
更新日期：2008-08-19 00:00:00
abstract：:Few suspension cells can be used for vaccine manufacturing today as they either do not meet requirements from health regulatory authorities or do not produce high virus titres. Two new avian designer cell lines (AGE1.CR and AGE1.CR.pIX) that have been adapted to grow in suspension in serum-free medium were evaluated f...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2009.05.083
更新日期：2009-08-06 00:00:00
abstract：:This paper presents the results of a global survey that aimed to collect information on country's immunization policy development processes, particularly on the presence and function of national Immunization Technical Advisory Groups (ITAGs). Characteristics of national ITAGs are described as well as attributes of the...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2009.07.089
更新日期：2010-04-19 00:00:00
abstract：BACKGROUND:Typhoid fever remains a major public health problem in low- and middle-income countries where children aged 2-14 years bear the greatest burden. Vi polysaccharide is poorly immunogenic in children <2 years of age, and protection in adults is modest. The limitations of Vi polysaccharide vaccines can be overco...
journal_title：Vaccine
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.vaccine.2018.05.038
更新日期：2018-06-18 00:00:00
abstract：:The effect of sublethal gamma-ray irradiation on the protection conferred by a nasal influenza vaccine was investigated in BALB/c mice. A radiation dose of 7 Gy was selected as the sublethal dose as this caused exacerbation of the influenza but was not lethal in the mouse model. Mice were irradiated 7 days before, on ...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/s0264-410x(99)00553-8
更新日期：2000-05-22 00:00:00
abstract：:The feasibility of a combined diphtheria-tetanus-acellular pertussis-hepatitis B (DTPa-HBV) vaccine was assessed and a comparison made of immunogenicity and reactogenicity to DTPa and HBV vaccines mixed in one syringe and to concomitant but separate injections as a primary vaccination course in three groups of infants...
journal_title：Vaccine
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0264-410x(97)00089-3
更新日期：1997-10-01 00:00:00
abstract：BACKGROUND:This study evaluated the immunogenicity and safety of quadrivalent meningococcal conjugate vaccine using tetanus (T) toxoid as carrier protein (MenACWY-TT) co-administered with combined diphtheria-tetanus-acellular pertussis vaccine (Tdap) versus their separate administration in adolescents and young adults....
journal_title：Vaccine
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.vaccine.2018.04.034
更新日期：2018-07-25 00:00:00
abstract：:Helicobacter pylori is a Gram-negative bacterial pathogen associated with gastritis, peptic ulceration, and gastric carcinoma. The bacteria express a strong urease activity which is known to be essential for colonization of gnotobiotic pigs and nude mice. UreA and UreB, two structural subunits of the active enzyme, we...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/s0264-410x(97)00247-8
更新日期：1998-03-01 00:00:00
abstract：:The potential of genetically fusing recombinant proteins to the simian immunodeficiency virus (SIV) Tat protein has been investigated. The recombinant SIV Tat protein was initially expressed in very low amounts in E. coli, but optimization of the coding sequence for translation in the bacterial host significantly impr...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2005.09.012
更新日期：2006-02-06 00:00:00
abstract：:HIV infection is characterized by chronic immune activation and the establishment of a pool of latently infected cells. Antiretroviral therapy (ART) can suppress viral load to undetectable levels in peripheral blood by standard measure, however immune activation/chronic inflammation and latent infection persist and af...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2020.04.015
更新日期：2020-06-02 00:00:00
abstract：:As a follow-up to the first AfroREB meeting, held in Grand Bassam (Côte d'Ivoire) in March 2008, African rabies experts of the AfroREB network met a second time to complete the evaluation of the rabies situation in Africa and define specific action plans. About 40 French speaking rabies specialists from northern, west...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2009.06.030
更新日期：2009-08-13 00:00:00
abstract：:Since its registration in 2002, Gudair® vaccine has become the key tool for managing paratuberculosis in sheep in Australia. This study was conducted to evaluate its effectiveness in reducing paratuberculosis prevalence in 12 flocks over more than one decade. Flocks with variable initial prevalence (5, 4 and 3 with lo...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2016.08.064
更新日期：2016-09-30 00:00:00
abstract：:Marek's disease virus (MDV) encodes a basic leucine zipper oncoprotein, Meq, which structurally resembles jun/fos family of transcriptional activators. It has been clearly demonstrated that deletion of Meq results in loss of transformation and oncogenic capacity of MDV. The rMd5ΔMeq virus provided superior protection ...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2012.05.043
更新日期：2012-07-20 00:00:00
abstract：:We examined potential risk factors on vaccine virus shedding and antibody seroresponse to human rotavirus vaccine (Rotarix) in Mexican infants. Two doses of Rotarix were administered to infants during the first two visits for their routine childhood immunization (∼8 and 15weeks of age) in Mexico City. Infant's charact...
journal_title：Vaccine
pub_type： 杂志文章
doi：10.1016/j.vaccine.2016.09.006
更新日期：2016-10-17 00:00:00
