Structural correlates of formal thought disorder in schizophrenia: An ultra-high field multivariate morphometry study.

abstract：BACKGROUND:Patients with schizophrenia show deviances in their dermatoglyphics, in particular reductions in palmar a-b ridge counts (ABRCs), which are evidence of an early developmental deviance. However, the severity or the origin of these ABRC changes has not been established. METHOD:(i) We examined the published li...

journal_title：Schizophrenia research

authors： Bramon E,Walshe M,McDonald C,Martín B,Toulopoulou T,Wickham H,van Os J,Fearon P,Sham PC,Fañanás L,Murray RM

更新日期：2005-06-15 00:00:00

abstract：:Assessment of depression in individuals who are considered to be at clinical high risk (CHR) for psychosis is important as high rates of depression have been reported in CHR individuals. The Calgary Depression Scale (CDSS) is the most widely used scale for assessing depression in schizophrenia. It has excellent psycho...

journal_title：Schizophrenia research

authors： Addington J,Shah H,Liu L,Addington D

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVE:The main goal of the present study was to analyze levels of cytokines of the interleukin family (IL-1α, IL-1β, IL-2, IL-4, IL-6, IL-8 and IL-10), interferon-gamma (IFN-γ), monocyte chemoattractant protein-1 (MCP1), tumor necrosis factor-alpha (TNF-α), and vascular endothelial and endothelial growth factors (V...

journal_title：Schizophrenia research

authors： Haring L,Koido K,Vasar V,Leping V,Zilmer K,Zilmer M,Vasar E

更新日期：2015-12-01 00:00:00

abstract：:Catatonia is a severe psychomotor syndrome that frequently occurs in patients with schizophrenia spectrum disorders (SSD). Accumulating neuroimaging evidence suggests orbitofrontal, frontoparietal and cerebellar network dysfunction in catatonia. Very little is known about contributions of brainstem regions (as part of...

journal_title：Schizophrenia research

authors： Fritze S,Thieme CE,Kubera KM,Northoff G,Schmitgen MM,Wolf RC,Hirjak D

更新日期：2020-10-01 00:00:00

abstract：:Astrocytic markers glial fibrillary acidic protein (GFAP) and connexin 43 (CX43) are known to have altered expression in brains of subjects with psychiatric disorders including autism and major depression. The current study investigated whether GFAP and CX43 expressions are affected by several commonly used psychotrop...

journal_title：Schizophrenia research

authors： Fatemi SH,Folsom TD,Reutiman TJ,Pandian T,Braun NN,Haug K

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Depressive symptoms frequently accompany schizophrenia. Older patients constitute the fastest growing segment of the schizophrenia population. With regard to the risk factors associated with depression, it is uncertain to which extent older schizophrenia patients differ from their age peers in the community....

journal_title：Schizophrenia research

authors： Meesters PD,Comijs HC,Sonnenberg CM,Hoogendoorn AW,de Haan L,Eikelenboom P,Beekman AT,Stek ML

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Recent research has identified impairment in processing speed, measured by the digit-symbol substitution task, as central to the cognitive deficit in schizophrenia. However, the underlying cognitive correlates of this impairment remain unknown. METHODS:A sample of cases (N=125) meeting DSM-IV criteria for s...

journal_title：Schizophrenia research

authors： Knowles EE,Weiser M,David AS,Dickinson D,Glahn D,Gold J,Davidson M,Reichenberg A

更新日期：2012-12-01 00:00:00

abstract：:Social dysfunction is a hallmark of schizophrenia. Social isolation may increase individuals' risk for psychotic symptom exacerbation and relapse. Monitoring and timely detection of shifts in social functioning are hampered by the limitations of traditional clinic-based assessment strategies. Ubiquitous mobile technol...

journal_title：Schizophrenia research

authors： Buck B,Scherer E,Brian R,Wang R,Wang W,Campbell A,Choudhury T,Hauser M,Kane JM,Ben-Zeev D

更新日期：2019-06-01 00:00:00

abstract：:Sustained attention deficits and high rates of smoking are often observed in patients with schizophrenia. This has led to the hypothesis that patients may smoke as an attempt to ameliorate cognitive deficits related to abnormal nicotinic structure and function. Continuous performance tasks (CPT) are often used to inde...

journal_title：Schizophrenia research

authors： Roth M,Hong LE,McMahon RP,Fuller RL

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Structural pathology in the hippocampus is well-documented in schizophrenia, but brain functional changes have not been consistently found. We used spatial navigation in a virtual reality environment, a task that is known to produce robust hippocampal activation in healthy subjects, to examine task-related a...

journal_title：Schizophrenia research

authors： Salgado-Pineda P,Landin-Romero R,Portillo F,Bosque C,Pomes A,Spanlang B,Franquelo JC,Teixido C,Sarró S,Salvador R,Slater M,Pomarol-Clotet E,McKenna PJ

更新日期：2016-04-01 00:00:00

abstract：:Our study aimed to investigate how recovery styles influence 12-month clinical outcome in first-episode psychosis patients. We hypothesised that patients who use an integrative recovery style would have better outcome than those who seal over. A total of 196 first-episode psychosis patients from the Early Psychosis In...

journal_title：Schizophrenia research

authors： Thompson KN,McGorry PD,Harrigan SM

更新日期：2003-07-01 00:00:00

abstract：:Task set maintenance and switching deficits are robust in schizophrenia. However, little is known about how these constructs are related to one another. The development of an improved understanding of set switching and maintenance deficits in schizophrenia requires that these constructs be explicated in terms of eleme...

journal_title：Schizophrenia research

authors： Kieffaber PD,Kappenman ES,Bodkins M,Shekhar A,O'Donnell BF,Hetrick WP

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:To develop a pharmacokinetic-pharmacodynamic (PK-PD) model using individual-level data of Positive and Negative Syndrome Scale (PANSS) total score to characterize the antipsychotic drug effect taking into account the placebo effect and dropout rate. In addition, a clinical utility (CU) criterion that describ...

journal_title：Schizophrenia research

authors： Pilla Reddy V,Kozielska M,Suleiman AA,Johnson M,Vermeulen A,Liu J,de Greef R,Groothuis GM,Danhof M,Proost JH

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:Self-referential processing (i.e. linking internal and external stimuli to one's own self) has received scant attention thus far in schizophrenia. This type of processing is a key component of social cognition and thought to be important for adaptive social functioning. Memory studies in healthy subjects hav...

journal_title：Schizophrenia research

authors： Harvey PO,Lee J,Horan WP,Ochsner K,Green MF

更新日期：2011-04-01 00:00:00

abstract：:A number of reports of genetic association of human leucocyte antigens (HLA) and alleles with schizophrenia have recently been published. A schizophrenia locus on chromosome 6p near the HLA region has also been reported, on the basis of linkage studies. We have therefore reviewed the investigations of association of H...

journal_title：Schizophrenia research

authors： Wright P,Nimgaonkar VL,Donaldson PT,Murray RM

更新日期：2001-01-15 00:00:00

abstract：:Jumping to conclusions and bias against disconfirmatory evidence are two cognitive biases common in people with psychotic-like experiences and psychosis. However, many participants show comprehension problems doing traditional tasks; new paradigms with additional applied scenarios are thus needed. A large MTurk commun...

journal_title：Schizophrenia research

authors： Scheunemann J,Gawęda Ł,Reininger KM,Jelinek L,Hildebrandt H,Moritz S

更新日期：2020-02-01 00:00:00

abstract：:The construct of Expressed Emotion (EE) is a reliable predictor of relapse in psychotic disorders globally. However, cultural differences in the level and manifestation of EE have been reported. This review was conducted in line with PRISMA guidelines to demonstrate the distribution of EE and its domains cross-cultura...

journal_title：Schizophrenia research

authors： O'Driscoll C,Sener SB,Angmark A,Shaikh M

更新日期：2019-06-01 00:00:00

abstract：:Adolescents meeting diagnostic criteria for schizotypal personality disorder (SPD) are presumed to be at risk for developing schizophrenia in adulthood, making them an important group for exploring the developmental trajectory of the disease. Deficits in executive functioning have been documented in schizophrenia pati...

journal_title：Schizophrenia research

authors： Diforio D,Walker EF,Kestler LP

更新日期：2000-04-07 00:00:00

abstract：BACKGROUND:Higher cognitive dysfunction, lower perceptual disturbance and its relation to the structures that implicate such processes have been considered as key features in patients with schizophrenia. However, little is known about the relationship between perceptual processing and structural deficits in ultra-high-...

journal_title：Schizophrenia research

authors： Shin KS,Jung WH,Kim JS,Jang JH,Hwang JY,Chung CK,Kwon JS

更新日期：2012-09-01 00:00:00

abstract：:Long-stay patients constitute a small proportion of all patients with schizophrenia, but in both VA and state psychiatric systems these patients account for a majority of the costs associated with treatment of the illness. VA and state patients would be expected to differ in several respects, including age at onset an...

journal_title：Schizophrenia research

authors： Harvey PD,Jacobsen H,Mancini D,Parrella M,White L,Haroutunian V,Davis KL

更新日期：2000-05-25 00:00:00

abstract：:Prenatal viral infection has been associated with development of schizophrenia and autism. Our laboratory has previously shown that viral infection causes deleterious effects on brain structure and function in mouse offspring following late first trimester (E9) administration of influenza virus. We hypothesized that l...

journal_title：Schizophrenia research

authors： Fatemi SH,Reutiman TJ,Folsom TD,Huang H,Oishi K,Mori S,Smee DF,Pearce DA,Winter C,Sohr R,Juckel G

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Numerous studies have examined a wide range of risk factors associated with violence among patients with schizophrenia. However, risk factors linked to different socio-cultural backgrounds remain unclear. OBJECTIVE:The objectives were to investigate factors associated with violence among Japanese patients w...

journal_title：Schizophrenia research

authors： Imai A,Hayashi N,Shiina A,Sakikawa N,Igarashi Y

更新日期：2014-12-01 00:00:00

abstract：:Genetic and environmental models of neuropsychiatric disease have grown exponentially over the last 20years. One measure that is often used to evaluate the translational relevance of these models to human neuropsychiatric disease is prepulse inhibition of startle (PPI), an operational measure of sensorimotor gating. D...

journal_title：Schizophrenia research

authors： Khan A,Powell SB

更新日期：2018-08-01 00:00:00

abstract：:Schizophrenia has generally been viewed as having a unique preschizophrenia personality or destructive to the personality post-onset. This view is reflected in the scarcity of studies of personality in schizophrenia with the exception of schizotypal personality considered by many as an endophenotype of schizophrenia. ...

journal_title：Schizophrenia research

authors： Lewine R,Martin M,Hart M

更新日期：2017-11-01 00:00:00

abstract：:The dot pattern expectancy (DPX) task has been strongly recommended as a measure of goal maintenance, which is impaired in schizophrenia patients. The current event-related potential (ERP) study was designed mainly to identify the ERP component that could represent the goal maintenance process of the DPX task as index...

journal_title：Schizophrenia research

authors： Shen A,Zhao W,Han B,Zhang Q,Zhang Z,Chen X,Zhai J,Chen M,Du B,Deng X,Ji F,Wang C,Xiang YT,Wu H,Dong Q,Chen C,Li J

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:The Positive and Negative Syndrome Scale (PANSS) total score is widely used to assess antipsychotic efficacy, however schizophrenia is a multi-dimensional disorder. We conducted a 5-factor analysis for evaluating the efficacy of iloperidone vs. placebo across these different domains in the treatment of schiz...

journal_title：Schizophrenia research

authors： Citrome L,Meng X,Hochfeld M

更新日期：2011-09-01 00:00:00

abstract：:The natural history of neurocognitive impairments in schizophrenia is unclear. We aimed to characterise this in an epidemiological first-episode cohort and relate it to long-term outcome. All but 1 of 112 first-episode psychosis cases ascertained from a geographical catchment area were traced at 10-12 years. Neurocogn...

journal_title：Schizophrenia research

authors： Stirling J,White C,Lewis S,Hopkins R,Tantam D,Huddy A,Montague L

更新日期：2003-12-15 00:00:00

abstract：BACKGROUND:Despite the upsurge of research regarding cognitive impairment in schizophrenia we still lack adequate understanding of the executive functioning of patients in symptomatic remission. Moreover, the cognitive functioning of patients in partial remission has not been studied previously although they comprise a...

journal_title：Schizophrenia research

authors： Braw Y,Benozio A,Levkovitz Y

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:This study sought to evaluate levels of insight and change in insight in subjects with schizophrenia and other major psychiatric disorders. This study also evaluated the relationship of insight to acute psychopathology. METHOD:One-hundred and eighty-seven subjects consecutively admitted to an acute care psyc...

journal_title：Schizophrenia research

authors： Weiler MA,Fleisher MH,McArthur-Campbell D

更新日期：2000-09-29 00:00:00

abstract：BACKGROUND:We aimed to examine the association between illicit substance use and age at onset in psychotic disorders in an Australian cohort. METHODS:Retrospectively acquired information on substance use during the year prior to illness onset was collected from 1642 participants enrolled in the Australian National 201...

journal_title：Schizophrenia research

authors： Stefanis NC,Dragovic M,Power BD,Jablensky A,Castle D,Morgan VA

更新日期：2014-07-01 00:00:00