Abstract:
BACKGROUND:Depressive symptoms frequently accompany schizophrenia. Older patients constitute the fastest growing segment of the schizophrenia population. With regard to the risk factors associated with depression, it is uncertain to which extent older schizophrenia patients differ from their age peers in the community. METHODS:We assessed self-reported depressive symptoms in an epidemiological sample of older Dutch community-living patients with schizophrenia or schizoaffective disorder (N=99; mean age 67years). Demographic, clinical and social variables were evaluated for their predictive value on the level of depressive symptoms. A comparison group, proportionally matched for age and gender, was recruited from a community study. RESULTS:In the schizophrenia group, 47.5% reported depressive symptoms at a level indicating clinically relevant depression, in contrast to 12.1% in their age peers (odds ratio 6.55; 95% CI, 3.19-13.48; p<0.001). This difference could not be explained by differential exposure to the evaluated general risk factors. In both groups, functional limitations were the strongest predictor of depressive symptoms. In the patient group, chronic physical disorders and lack of a confidant were predictors, while a diagnosis of schizoaffective disorder (vs. schizophrenia) was the only disorder-related risk factor that contributed to depressive symptoms, with marginal significance. CONCLUSION:The high rate of depressive symptoms in this epidemiological sample of older schizophrenia patients confirms that these symptoms frequently accompany this severe mental illness in late life. With physical and social factors as important predictors of depressive symptoms, risk factors for depression are more comparable between older schizophrenia patients and their age peers than is often assumed.
journal_name
Schizophr Resjournal_title
Schizophrenia researchauthors
Meesters PD,Comijs HC,Sonnenberg CM,Hoogendoorn AW,de Haan L,Eikelenboom P,Beekman AT,Stek MLdoi
10.1016/j.schres.2014.05.002subject
Has Abstractpub_date
2014-08-01 00:00:00pages
285-91issue
1-3eissn
0920-9964issn
1573-2509pii
S0920-9964(14)00229-1journal_volume
157pub_type
杂志文章abstract::Jumping to conclusions and bias against disconfirmatory evidence are two cognitive biases common in people with psychotic-like experiences and psychosis. However, many participants show comprehension problems doing traditional tasks; new paradigms with additional applied scenarios are thus needed. A large MTurk commun...
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更新日期:2013-12-01 00:00:00
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journal_title:Schizophrenia research
pub_type: 杂志文章
doi:10.1016/j.schres.2012.08.020
更新日期:2012-12-01 00:00:00
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journal_title:Schizophrenia research
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pub_type: 杂志文章
doi:10.1016/j.schres.2003.09.011
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pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2009-07-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.schres.2005.12.853
更新日期:2006-03-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.schres.2007.11.018
更新日期:2008-02-01 00:00:00
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更新日期:2014-08-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.schres.2005.04.001
更新日期:2005-09-15 00:00:00
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pub_type: 杂志文章
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更新日期:2006-01-31 00:00:00
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pub_type: 杂志文章
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更新日期:2017-06-01 00:00:00